Lipid oxidation controls peptide self-assembly near membranes through a surface attraction mechanism

Torsten John, Stefania Piantavigna, Tiara J. A. Dealey, Bernd Abel, Herre Jelger Risselada and Lisandra L. Martin

Chem. Sci., 2023, 14, 3730
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Partitioning of caffeine in lipid bilayers reduces membrane fluidity and increases membrane thickness

Adree Khondker, Alexander Dhaliwal, Richard J. Alsop, Jennifer Tang, Matilda Backholm, An-Chang Shi and Maikel C. Rheinstädter

Phys. Chem. Chem. Phys., 2017, 19, 7101
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Computational insights into lipid assisted peptide misfolding and aggregation in neurodegeneration

Abhilash Sahoo and Silvina Matysiak

Phys. Chem. Chem. Phys., 2019, 21, 22679
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Modulation of DEG/ENaCs by Amphiphiles Suggests Sensitivity to Membrane Alterations

Axel Schmidt, Rick J. Alsop, Rahul Rimal, Pia Lenzig, Sylvia Joussen, Natalie N. Gervasi, Adree Khondker, Stefan Gründer, Maikel C. Rheinstädter and Dominik Wiemuth

Biophysical Journal, 2018, 114, 1321
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The Molecular Structure of Human Red Blood Cell Membranes from Highly Oriented, Solid Supported Multi-Lamellar Membranes

Sebastian Himbert, Richard J. Alsop, Markus Rose, Laura Hertz, Alexander Dhaliwal, Jose M. Moran-Mirabal, Chris P. Verschoor, Dawn M. E. Bowdish, Lars Kaestner, Christian Wagner and Maikel C. Rheinstädter

Sci Rep, 2017, 7
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A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC)

Axel Schmidt, Daniel Löhrer, Richard J. Alsop, Pia Lenzig, Adrienne Oslender-Bujotzek, Monika Wirtz, Maikel C. Rheinstädter, Stefan Gründer and Dominik Wiemuth

Journal of Biological Chemistry, 2016, 291, 24551
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Membrane-Modulating Drugs can Affect the Size of Amyloid-β25–35 Aggregates in Anionic Membranes

Adree Khondker, Richard J. Alsop, Sebastian Himbert, Jennifer Tang, An-Chang Shi, Adam P. Hitchcock and Maikel C. Rheinstädter

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-30431-8

De novo aggregation of Alzheimer’s Aβ25-35 peptides in a lipid bilayer

Amy K. Smith and Dmitri K. Klimov

Sci Rep, 2019, 9
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Membrane-Accelerated Amyloid-β Aggregation and Formation of Cross-β Sheets

Adree Khondker, Richard Alsop and Maikel Rheinstädter

Membranes, 2017, 7, 49
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Surface-Directed Structural Transition of Amyloidogenic Aggregates and the Resulting Neurotoxicity

Hao Chen, Dan Sun, Yin Tian, Haiming Fan, Yonggang Liu, Ludmilla A. Morozova-Roche and Ce Zhang

ACS Omega, 2020, 5, 2856
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An agent-based model to investigate microbial initiation of Alzheimer’s via the olfactory system

Shalini Sundar, Carly Battistoni, Ryan McNulty, Fernando Morales, Jonathan Gorky, Henry Foley and Prasad Dhurjati

Theor Biol Med Model, 2020, 17
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The Effects of Resveratrol, Caffeine, β‐Carotene, and Epigallocatechin Gallate (EGCG) on Amyloid‐β25--35 Aggregation in Synthetic Brain Membranes

Isabella P. Gastaldo, Sebastian Himbert, Udbhav Ram and Maikel C. Rheinstädter

Molecular Nutrition Food Res, 2020, 64
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Calcium ions do not influence the Aβ(25–35) triggered morphological changes of lipid membranes

Sergei Kurakin, Oleksandr Ivankov, Ermuhammad Dushanov, Tatiana Murugova, Elena Ermakova, Sergey Efimov, Timur Mukhametzyanov, Svetlana Smerdova, Vladimir Klochkov, Alexander Kuklin and Norbert Kučerka

Biophysical Chemistry, 2024, 313, 107292
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Aggregation Behavior of Amyloid Beta Peptide Depends Upon the Membrane Lipid Composition

Lipika Mirdha

J Membrane Biol, 2024, 257, 151
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Lysine Acetylation Changes the Mechanism of Aβ25–35 Peptide Binding and Dimerization in the DMPC Bilayer

Elias Khayat, Bryan M. Delfing, Xavier Laracuente, Audrey Olson, Christopher Lockhart and Dmitri K. Klimov

ACS Chem. Neurosci., 2023, 14, 494
DOI: 10.1021/acschemneuro.2c00722

Curcumin and Homotaurine Suppress Amyloid-β25–35 Aggregation in Synthetic Brain Membranes

Xingyuan Zou, Sebastian Himbert, Alix Dujardin, Janos Juhasz, Samantha Ros, Harald D. H. Stöver and Maikel C. Rheinstädter

ACS Chem. Neurosci., 2021, 12, 1395
DOI: 10.1021/acschemneuro.1c00057

Arrangement of lipid vesicles and bicelle-like structures formed in the presence of Aβ(25–35) peptide

Sergei Kurakin, Dina Badreeva, Ermuhammad Dushanov, Artyom Shutikov, Sergey Efimov, Ayzira Timerova, Timur Mukhametzyanov, Tatiana Murugova, Oleksandr Ivankov, Kahramon Mamatkulov, Grigory Arzumanyan, Vladimir Klochkov and Norbert Kučerka

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2024, 1866, 184237
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Phosphorylation Promotes Aβ25–35 Peptide Aggregation within the DMPC Bilayer

Elias Khayat, Dmitri K. Klimov and Amy K. Smith

ACS Chem. Neurosci., 2020, 11, 3430
DOI: 10.1021/acschemneuro.0c00541

Perspective on the role of the physical properties of membranes in neurodegenerative and infectious diseases

Isabella Passos Gastaldo, Hannah V. Rheinstädter and Maikel C. Rheinstädter

Applied Physics Letters, 2020, 117
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Anchoring of Amyloid-β onto Polyunsaturated Phospholipid Membranes

Ruikang Yuan and Haohao Huang

Journal of Biomolecular Structure and Dynamics, 2023, 41, 1098
DOI: 10.1080/07391102.2021.2016488

Curcumin Protects Membranes through a Carpet or Insertion Model Depending on Hydration

Richard J. Alsop, Alexander Dhaliwal and Maikel C. Rheinstädter

Langmuir, 2017, 33, 8516
DOI: 10.1021/acs.langmuir.7b01562

Met35 Oxidation Hinders Aβ25-35 Peptide Aggregation within the Dimyristoylphosphatidylcholine Bilayer

Elias Khayat, Christopher Lockhart, Bryan M. Delfing, Amy K. Smith and Dmitri K. Klimov

ACS Chem. Neurosci., 2021, 12, 3225
DOI: 10.1021/acschemneuro.1c00407

Probing the Protein Folding Energy Landscape: Dissociation of Amyloid-β Fibrils by Laser-Induced Plasmonic Heating

Dongdong Lin, Zhenyu Qian, Massimo Bagnani, Miguel A. Hernández-Rodríguez, Julio Corredoira-Vázquez, Guanghong Wei, Luís D. Carlos and Raffaele Mezzenga

ACS Nano, 2023, 17, 9429
DOI: 10.1021/acsnano.3c01489