Issue 20, 2014

Convergent routes to substituted naphthylamides

Abstract

Practical, convergent routes to variously substituted 1- and 2-naphthylamides have been developed. They exploit the ability of xanthates to undergo both intermolecular radical additions to vinyl pivalate and intramolecular radical cyclisations to aromatic rings. In the case of 1-naphthylamides, the existence of an intramolecular hydrogen bond was used to facilitate the cyclisation step.

Graphical abstract: Convergent routes to substituted naphthylamides

Supplementary files

Article information

Article type
Paper
Submitted
13 фев 2014
Accepted
13 мар 2014
First published
13 мар 2014

Org. Biomol. Chem., 2014,12, 3251-3264

Convergent routes to substituted naphthylamides

N. D. M. Tran and S. Z. Zard, Org. Biomol. Chem., 2014, 12, 3251 DOI: 10.1039/C4OB00339J

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