Issue 21, 2009

Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

Abstract

The copper(I)-catalyzed synthesis of a range of primary anilines from electron-rich and electron-deficient aryl halides including aryl chlorides has been achieved with aqueous ammonia, avoiding the need for inert atmosphere, expensive catalysts and ligands, anhydrous solvents, and additional base or other additives.

Graphical abstract: Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

Supplementary files

Article information

Article type
Communication
Submitted
02 мар 2009
Accepted
14 апр 2009
First published
27 апр 2009

Chem. Commun., 2009, 3035-3037

Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

H. Xu and C. Wolf, Chem. Commun., 2009, 3035 DOI: 10.1039/B904188E

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