Payal Rani, Sandhya Chahal, Anju Ranolia, Devendra Kumar, Ramesh Kataria, Parvin Kumar, Devender Singh, Anil Duhan, Vibhu Jha, Muhammad Wahajuddin, Gaurav Joshi and Jayant Sindhu
RSC Med. Chem., 2025,16, 2832-2847
Abstract
Sulfenylated amino pyrazoles: inhibitors of acetylcholinesterase and butyrylcholinesterase.
Mihaela-Liliana Ţînţaş, Ludovic Peauger, Anaïs Barré, Cyril Papamicaël, Thierry Besson, Jana Sopkovà-de Oliveira Santos, Vincent Gembus and Vincent Levacher
RSC Med. Chem., 2024,15, 963-980
Abstract
Promising multitargets ligands in Alzheimer's disease: sequential BuChE and DYRK1A/CLK1 kinases inhibition.
Shraddha Manish Gupta, Ashok Behera, Neetesh K. Jain, Avanish Tripathi, Dinesh Rishipathak, Siddharth Singh, Nafees Ahemad, Meryem Erol and Devendra Kumar
RSC Adv., 2023,13, 26344-26356
Abstract
Leading pathological markers of Alzheimer's disease (AD) include Acetylcholinesterase (AChE), Butyrylcholinesterase (BuChE), Amyloid beta (Aβ) and reactive oxygen species (ROS).
Sunil Kumar, Amritha Manoharan, Jayalakshmi J, Mohamed A. Abdelgawad, Wael A. Mahdi, Sultan Alshehri, Mohammed M. Ghoneim, Leena K. Pappachen, Subin Mary Zachariah, T. P. Aneesh and Bijo Mathew
RSC Adv., 2023,13, 9513-9529
Abstract
Alzheimer's disease (AD), a neurodegenerative condition associated with ageing, can occur.
Vasco Cachatra, Alice Martins, Maria Conceição Oliveira, Maria Cristina Oliveira, Lurdes Gano, António Paulo, Óscar López, José G. Fernández-Bolaños, Marialessandra Contino, Nicola Antonio Colabufo, David Evans, Teresa Man and Amélia Pilar Rauter
Org. Biomol. Chem., 2025,23, 3845-3859
From themed collection:
Articles behind our 2025 journal covers
Abstract
A multidisciplinary study of purine nucleoside selective BuChE inhibitors, covering docking, synthesis, biological evaluation and cytotoxic assays.