A Pd-catalyzed four-component dual carbonylative approach for cascade synthesis of 2-aryl quinazolinones has been developed with ammonium carbamate as an ammonia precursor and oxalic acid as a bifunctional reagent acting as CO and C-atom surrogate.
This review summarizes the recent progress in the field of the synthesis of N-heterocyclic skeletons through three types of conversion reactions of nitriles using transition metal-catalyzed and metal-free promoted strategies.
This review summarizes the recent advances in the photo-promoted synthesis of polycyclic quinazolinones from unactivated alkene-tethered quinazolinones over the past five years (2021–2025).
A base-promoted atom economical and unexpectedly selective cyclization strategy was developed for the synthesis of indole-fused azepino[2,1-b]quinazolinones and spiroindole-pyrrolo[2,1-b]quinazolinones.
Biologically active [1,5]diazocino[2,1-b]quinazolinones were synthesized via base-promoted [4 + 4] cycloaddition of 2-alkynyl quinazolinones with aza-ortho-quinone methides.