Synthetic studies towards putative yuremamine using an iterative C(sp3)–H arylation strategy

Matthew B. Calvert and Jonathan Sperry

Org. Biomol. Chem., 2016, 14, 5728
DOI: 10.1039/C6OB00110F

Diastereoselective palladium-catalyzed C(sp3)–H cyanomethylation of amino acid and carboxylic acid derivatives

Sumit Garai, Krishna Gopal Ghosh, Ashik Biswas, Sushobhan Chowdhury and Devarajulu Sureshkumar

Chem. Commun., 2022, 58, 7793
DOI: 10.1039/D2CC03106J

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

Carlo Sambiagio, David Schönbauer, Remi Blieck, Toan Dao-Huy, Gerit Pototschnig, Patricia Schaaf, Thomas Wiesinger, Muhammad Farooq Zia, Joanna Wencel-Delord, Tatiana Besset, Bert U. W. Maes and Michael Schnürch

Chem. Soc. Rev., 2018, 47, 6603
DOI: 10.1039/C8CS00201K

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

Jian He, Masayuki Wasa, Kelvin S. L. Chan, Qian Shao and Jin-Quan Yu

Chem. Rev., 2017, 117, 8754
DOI: 10.1021/acs.chemrev.6b00622

Direct Palladium‐Catalyzed β‐Arylation of Lactams

Ming Chen, Feipeng Liu and Guangbin Dong

Angew Chem Int Ed, 2018, 57, 3815
DOI: 10.1002/anie.201800958

Pd(0)-Catalyzed Bidentate Auxiliary Directed Enantioselective Benzylic C–H Arylation of 3-Arylpropanamides Using the BINOL Phosphoramidite Ligand

Hua-Rong Tong, Sujuan Zheng, Xinghua Li, Zhiqiang Deng, Hao Wang, Gang He, Qian Peng and Gong Chen

ACS Catal., 2018, 8, 11502
DOI: 10.1021/acscatal.8b03654

Recent Advances on Amino Acid Modifications via C–H Functionalization and Decarboxylative Functionalization Strategies

Santanu Mondal and Sushobhan Chowdhury

Adv Synth Catal, 2018, 360, 1884
DOI: 10.1002/adsc.201800011

Direct Palladium‐Catalyzed β‐Arylation of Lactams

Ming Chen, Feipeng Liu and Guangbin Dong

Angewandte Chemie, 2018, 130, 3877
DOI: 10.1002/ange.201800958

Selective Removal of Aminoquinoline Auxiliary by IBX Oxidation

Zhiguo Zhang, Xiang Li, Mengmeng Song, Yameng Wan, Dan Zheng, Guisheng Zhang and Gong Chen

J. Org. Chem., 2019, 84, 12792
DOI: 10.1021/acs.joc.9b01362

Palladium-Catalyzed Enantioselective Directed C(sp3)–H Functionalization Using C5-Substituted 8-Aminoquinoline Auxiliaries

Yi Huang, Xiaoyan Lv, Hua-Rong Tong, Wenji He, Ziqian Bai, Hao Wang, Gang He and Gong Chen

Org. Lett., 2024, 26, 94
DOI: 10.1021/acs.orglett.3c03688

Native Amine-Directed ortho-C–H Halogenation and Acetoxylation /Condensation of Benzylamines

Pratibha Chand-Thakuri, Indunil Alahakoon, Daniel Liu, Mohit Kapoor, John F. Kennedy, Kenneth W. Jenkins, Allison M. Rabon and Michael C. Young

Synthesis, 2022, 54, 341
DOI: 10.1055/a-1625-9095

Transamidation and Decarbonylation of N-Phthaloyl-Amino Acid Amides Enabled by Palladium-Catalyzed Selective C–N Bond Cleavage

Hao-Yu Zhang, Xuan-Wen Tao, Li-Na Yi, Zhi-Gang Zhao and Qiang Yang

J. Org. Chem., 2022, 87, 231
DOI: 10.1021/acs.joc.1c02245

Palladium-Catalyzed β-C–H Arylation of Alkyl Carboxamides with Sterically Hindered Aryl Iodides Using ortho-Sulfinyl Aniline Auxiliaries

Delong Mu, Fang Gao, Gong Chen and Gang He

ACS Catal., 2017, 7, 1880
DOI: 10.1021/acscatal.6b03661

Utilizing Native Directing Groups: Synthesis of a Selective IKur Inhibitor, BMS-919373, via a Regioselective C–H Arylation

Steven R. Wisniewski, Jason M. Stevens, Miao Yu, Kenneth J. Fraunhoffer, Evan O. Romero and Scott A. Savage

J. Org. Chem., 2019, 84, 4704
DOI: 10.1021/acs.joc.8b02254

Ni/NHC-catalyzed C5-H alkylation and alkenylation of challenging furan(thiophene)-2-carboxaldehydes enabled by recyclable imine protecting group

Olga V. Khazipova, Oleg V. Khazipov, Konstantin E. Shepelenko, Alexey S. Kashin, Yu Zhang, Victor M. Chernyshev and Valentine P. Ananikov

Commun Chem, 2025, 8
DOI: 10.1038/s42004-025-01653-5

One-Pot C–H Arylation/Lactamization Cascade Reaction of Free Benzylamines

Pratibha Chand-Thakuri, Vinod G. Landge, Mohit Kapoor and Michael C. Young

J. Org. Chem., 2020, 85, 6626
DOI: 10.1021/acs.joc.0c00542

Reverse Regioselective Dicarbofunctionalization via Anti‐Michael‐Type Addition

Hirotsugu Suzuki, Ryota Moro and Takanori Matsuda

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202505391

Organocatalytic Cloke–Wilson Rearrangement: Carbocation-Initiated Tandem Ring Opening/Cyclization of Cyclopropanes under Neutral Conditions

Guisheng Zhang, Liming Chen, Zhaokang Hu, Zhiguo Zhang, Jingjing Bi, Mengjuan Li and Xingjie Zhang

J. Org. Chem., 2023, 88, 1003
DOI: 10.1021/acs.joc.2c02415

Reverse Regioselective Dicarbofunctionalization via Anti‐Michael‐Type Addition

Hirotsugu Suzuki, Ryota Moro and Takanori Matsuda

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202505391

Isothiourea-catalysed chemo- and enantioselective [2,3]-sigmatropic rearrangements of N,N-diallyl allylic ammonium ylides

Thomas H. West, Stéphanie S.M. Spoehrle and Andrew D. Smith

Tetrahedron, 2017, 73, 4138
DOI: 10.1016/j.tet.2017.01.062

Bidentate Directing Groups: An Efficient Tool in C–H Bond Functionalization Chemistry for the Expedient Construction of C–C Bonds

Supriya Rej, Yusuke Ano and Naoto Chatani

Chem. Rev., 2020, 120, 1788
DOI: 10.1021/acs.chemrev.9b00495

Ligand-Enabled ortho-Arylation of (hetero)Aromatic Acids with 2,6-Disubstituted Aryl Halides

Xianglin Luo, Zhewei Li, Yuzhen Zheng, Yueping Lin, Huanfeng Jiang, Lukas J. Gooßen, Ming Lei and Liangbin Huang

ACS Catal., 2023, 13, 12104
DOI: 10.1021/acscatal.3c03168

Regioselective β-Csp3-Arylation of β-Alanine: An Approach for the Exclusive Synthesis of Diverse β-Aryl-β-amino Acids

Sushobhan Chowdhury, Roopal Vaishnav, Namita Panwar and Wahajul Haq

J. Org. Chem., 2019, 84, 2512
DOI: 10.1021/acs.joc.8b02887