Cross Reference Logo
Citations to this article as recorded by CrossRef and RSC Journals (513 citations).

A dual-responsive colorimetric probe for the detection of Cu2+ and Ni2+ species in real water samples and human serum
Guoxing Yin, Jingfeng Yao, Sai Hong, Yinuo Zhang, Zhaohua Xiao, Ting Yu, Haitao Li and Peng Yin
Analyst, 2019, 144, 6962
DOI: 10.1039/C9AN01451A

Emerging chemical tools and techniques for tracking biological manganese
Sayani Das, Kaustav Khatua, Ananya Rakshit, Asuncion Carmona, Anindita Sarkar, Subha Bakthavatsalam, Richard Ortega and Ankona Datta
Dalton Trans., 2019, 48, 7047
DOI: 10.1039/C9DT00508K

Tetraphenylethylene AIEgen bearing thiophenylbipyridine receptor for selective detection of copper(ii) ion
Dinesh N. Nadimetla and Sheshanath V. Bhosale
New J. Chem., 2021, 45, 7614
DOI: 10.1039/D1NJ01001H

Novel fluorescent anthracene–bodipy dyads displaying sensitivity to pH and turn-on behaviour towards Cu(ii) ions
A. Vanessa Saura, M. Isabel Burguete, Francisco Galindo and Santiago V. Luis
Org. Biomol. Chem., 2017, 15, 3013
DOI: 10.1039/C7OB00274B

Iridium tetrazolato complexes as efficient protein staining agents
Ling Gao, Luyao Chen, Yu Peng, Yibo Zhao, Jianhua Dong, Ziwang Mao, Junli Jia and Yuyang Zhou
Dalton Trans., 2022, 51, 16870
DOI: 10.1039/D2DT02564G

Pentafluorophenyl dipyrrin as probe for transition metal ion detection and bioremediation in Bacillus subtilis and Bacillus cereus
Dijo Prasannan and Chellaiah Arunkumar
New J. Chem., 2017, 41, 11190
DOI: 10.1039/C7NJ02157G

Towards multimodal cellular imaging: optical and X-ray fluorescence
Marcus E. Graziotto, Clinton J. Kidman, Liam D. Adair, Simon A. James, Hugh H. Harris and Elizabeth J. New
Chem. Soc. Rev., 2023, 52, 8295
DOI: 10.1039/D3CS00509G

Self-enhanced photoelectrochemical sensor based on a Schottky heterostructure organic electron donor matrix
Min Chen, Jiang Guo, Fangjing Mo, Hui Meng, Wangqing Yu and Yingzi Fu
Chem. Commun., 2022, 58, 455
DOI: 10.1039/D1CC04500H

2-Hydroxy-5-ethylphenylphosphonic acid and its application in carbon dot modification: synthesis, protonation, spectral properties and specific recognition of copper(ii) ions
Jiaxin Dong, Galina S. Tsebrikova, Yuliana I. Rogacheva, Vitaly P. Solov'ev, Natalya S. Nikolaeva, Mariya A. Lapshina, Irina S. Ivanova, Andrey B. Ilyukhin, Serafima S. Slobodskaia, Vladimir E. Baulin, Baoqiang Li and Aslan Yu. Tsivadze
Dalton Trans., 2025, 54, 17267
DOI: 10.1039/D5DT02093J

Stoichiometry-controlled cycloaddition of nitrilimines with unsymmetrical exocyclic dienones: microwave-assisted synthesis of novel mono- and dispiropyrazoline derivatives
Houda Gazzeh, Sarra Boudriga, Moheddine Askri, Abderrahim Khatyr, Michael Knorr, Carsten Strohmann, Christopher Golz, Yoann Rousselin and Marek M. Kubicki
RSC Adv., 2016, 6, 49868
DOI: 10.1039/C6RA09703K

Carbon dots–quinoline derivative nanocomposite: facile synthesis and application as a “turn-off” fluorescent chemosensor for detection of Cu2+ ions in tap water
Qian Li, Qitong Huang, Jie-Ji Zhu, Wen-Gang Ji and Qing-Xiao Tong
RSC Adv., 2016, 6, 87230
DOI: 10.1039/C6RA21034A

Visualizing mitochondria and mouse intestine with a fluorescent complex of a naphthalene-based dipolar dye and serum albumin
Jong Min An, Heejo Moon, Yejin Kim, Sangrim Kang, Youngseo Kim, Yuna Jung, Sungnam Park, Peter Verwilst, B. Moon Kim, Jae Seung Kang and Dokyoung Kim
J. Mater. Chem. B, 2020, 8, 7642
DOI: 10.1039/D0TB01314E

Rational design of a water-soluble, lipid-compatible fluorescent probe for Cu(i) with sub-part-per-trillion sensitivity
M. T. Morgan, A. M. McCallum and C. J. Fahrni
Chem. Sci., 2016, 7, 1468
DOI: 10.1039/C5SC03643G

A near-infrared fluorescent probe based on a novel rectilinearly π-extended rhodamine derivative and its applications
Jin Gong, Chang Liu, Xiaojie Jiao, Song He, Liancheng Zhao and Xianshun Zeng
J. Mater. Chem. B, 2020, 8, 2343
DOI: 10.1039/C9TB02739D

A self-assembled fluorescent organic nanoprobe and its application for sulfite detection in food samples and living systems
Tang Gao, Xiaozheng Cao, Peng Ge, Jie Dong, Shuqi Yang, Huan Xu, Yong Wu, Feng Gao and Wenbin Zeng
Org. Biomol. Chem., 2017, 15, 4375
DOI: 10.1039/C7OB00580F

Organosilatranes with thioester-anchored heterocyclic ring assembly: Cu2+ ion binding and fabrication of hybrid silica nanoparticles
Gurjaspreet Singh, Sunita Rani, Amandeep Saroa, Shally Girdhar, Jandeep Singh, Aanchal Arora, Darpandeep Aulakh and Mario Wriedt
RSC Adv., 2015, 5, 65963
DOI: 10.1039/C5RA09004K

Rational design of the first furoquinolinol based molecular systems for easy detection of Cu2+with potential applications in the area of membrane sensing
Manoj Kumar, Lokesh Kumar Kumawat, Vinod Kumar Gupta and Anuj Sharma
RSC Adv., 2015, 5, 106030
DOI: 10.1039/C5RA21862D

Reversible turn-on fluorescent Cu(ii) sensors: rather dream than reality?
Enrico Falcone, Angélique Sour, Vincent Lebrun, Gilles Ulrich, Laurent Raibaut and Peter Faller
Dalton Trans., 2019, 48, 14233
DOI: 10.1039/C9DT02864A

A new Schiff-based chemosensor for chromogenic sensing of Cu2+, Co2+and S2−in aqueous solution: experimental and theoretical studies
Cheol Hong Min, Sangkyun Na, Jae Eun Shin, Jae Kyun Kim, Tae Geun Jo and Cheal Kim
New J. Chem., 2017, 41, 3991
DOI: 10.1039/C7NJ00054E

Sensing in aqueous medium: mechanism and its application in the field of molecular recognition
Hemant Sharma, Navneet Kaur and Narinder Singh
Anal. Methods, 2015, 7, 7000
DOI: 10.1039/C5AY00483G

Simple and efficient rhodamine-derived VO2+ and Cu2+-responsive colorimetric and reversible fluorescent chemosensors toward the design of multifunctional materials
Daoyong Jiang, Xingying Xue, Guoning Zhang, Yucheng Wang, Han Zhang, Chao Feng, Zhifei Wang and Hong Zhao
J. Mater. Chem. C, 2019, 7, 3576
DOI: 10.1039/C8TC06296J

Design and synthesis of a push–pull arylene–vinylene terpyridyl conjugate: multifunctional behaviors exhibited by a single molecule
Amit Sil, Utsav Ghosh, Suman Dolai, Soumitra Manna, Apurba Maity and Sanjib K. Patra
Mater. Adv., 2022, 3, 5497
DOI: 10.1039/D1MA01179K

Sustained acid release from stimuli responsive organic crystals facilitates shape modulation in metal nanoparticle synthesis
Khalid Naim, Prodipta Samadder, Atikur Rahman, Subash Chandra Sahoo and Prakash P. Neelakandan
J. Mater. Chem. C, 2025, 13, 7093
DOI: 10.1039/D5TC00047E

Self-triggered click reaction in an Alzheimer's disease model:in situbifunctional drug synthesis catalyzed by neurotoxic copper accumulated in amyloid-β plaques
Zhi Du, Dongqin Yu, Xiubo Du, Peter Scott, Jinsong Ren and Xiaogang Qu
Chem. Sci., 2019, 10, 10343
DOI: 10.1039/C9SC04387J

A new bifunctional fluorescent sensor based on naphthalimide-functionalized silica nanoparticles for detection and adsorption of Cu2+ in aqueous solution
Xiangyang Zhang, Youming Shen, Hui Zhang, Junling Jin and Shibiao Zhou
Anal. Methods, 2015, 7, 8925
DOI: 10.1039/C5AY01481F

An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool
Sun Young Park, Woori Kim, Sun-Hee Park, Jinhyoung Han, Jinju Lee, Chulhun Kang and Min Hee Lee
Chem. Commun., 2017, 53, 4457
DOI: 10.1039/C7CC01430A

A novel “off–on” peptide fluorescent probe for the detection of copper and sulphur ions in living cells
Xue-jiao Wang, Jiang Zhou, Liang-chao Yuan, Jing-cheng Hou, Jiang Wu and Peng-cheng Lin
New J. Chem., 2024, 48, 5068
DOI: 10.1039/D3NJ05888C

Experimental and theoretical study of novel aminobenzamide–aminonaphthalimide fluorescent dyads with a FRET mechanism
Ángel L. García, Adrián Ochoa-Terán, Antonio Tirado-Guízar, Jesús Jara-Cortés, Georgina Pina-Luis, Hisila Santacruz Ortega, Victoria Labastida-Galván, Mario Ordoñez and Jorge Peón
RSC Adv., 2022, 12, 6192
DOI: 10.1039/D1RA09278B

Copper trafficking systems in cells: insights into coordination chemistry and toxicity
Jiyeon Han
Dalton Trans., 2023, 52, 15277
DOI: 10.1039/D3DT02166A

AIE + ESIPT activity-based NIR Cu2+ sensor with dye participated binding strategy
Jie Jiang, Haifeng Sun, Yanlei Hu, Gang Lu, Jiwei Cui and Jingcheng Hao
Chem. Commun., 2021, 57, 7685
DOI: 10.1039/D1CC02233D

[9]aneN3-based fluorescent receptors for metal ion sensing, featuring urea and amide functional groups
Alessandra Garau, Andrea Bencini, Alexander J. Blake, Claudia Caltagirone, Luca Conti, Francesco Isaia, Vito Lippolis, Riccardo Montis, Palma Mariani and Mariano Andrea Scorciapino
Dalton Trans., 2019, 48, 4949
DOI: 10.1039/C9DT00288J

Studies on a multifunctional chromo-fluorogenic sensor for dual channel recognition of Zn2+ and CN− ions in aqueous media: mimicking multiple molecular logic gates and memory devices
Khatereh Rezaeian, Hamid Khanmohammadi and Samira Gholizadeh Dogaheh
New J. Chem., 2018, 42, 2158
DOI: 10.1039/C7NJ04216G

Organelle-targeting ratiometric fluorescent probes: design principles, detection mechanisms, bio-applications, and challenges
Manoj Kumar Goshisht, Neetu Tripathi, Goutam Kumar Patra and Manohar Chaskar
Chem. Sci., 2023, 14, 5842
DOI: 10.1039/D3SC01036H

Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes
Jun-Long Zhu, Zheng Xu, Yangyang Yang and Lin Xu
Chem. Commun., 2019, 55, 6629
DOI: 10.1039/C9CC03299A

A simple design of fluorescent probes for indirect detection of β-lactamase based on AIE and ESIPT processes
Lu Peng, Lu Xiao, Yiwen Ding, Yu Xiang and Aijun Tong
J. Mater. Chem. B, 2018, 6, 3922
DOI: 10.1039/C8TB00414E

TiO2/CdS nanorod array-based photoelectrochemical sensing of Cu2+ in human serum samples
Kejun Feng, Minghui Yang, Fang Xie, Guiqiang Diao, Mingming Ou and Huanfeng Huang
Anal. Methods, 2017, 9, 6754
DOI: 10.1039/C7AY02625K

A paper-based biomimetic device for the reduction of Cu(ii) to Cu(i) – application to the sensing of Cu(ii)
Jordi Rull-Barrull, Martin d'Halluin, Erwan Le Grognec and François-Xavier Felpin
Chem. Commun., 2016, 52, 6569
DOI: 10.1039/C6CC02305C

A fluorescent probe based on pyrazoline with significant Stokes shifts for the detection of Cu2+ ions and its applications
Yajing Shang, Xinghu Wu and Haoting Luo
Anal. Methods, 2025, 17, 792
DOI: 10.1039/D4AY01772B

A new fluorophore displaying remarkable solvatofluorochromism and solid-state light emission, and serving as a turn-on fluorescent sensor for cyanide ions
Yosuke Kimura, Ikumi Kawajiri, Masanori Ueki, Takayuki Morimoto, Jun-ichi Nishida, Hiroshi Ikeda, Mirai Tanaka and Takeshi Kawase
Org. Chem. Front., 2017, 4, 743
DOI: 10.1039/C7QO00029D

Electrochemically assisted flexible lanthanide upconversion luminescence sensing of heavy metal contamination with high sensitivity and selectivity
Yuen-Ting Wong, Sin-Yi Pang, Ming-Kiu Tsang, Yan Liu, Haitao Huang, Siu-Fung Yu and Jianhua Hao
Nanoscale Adv., 2019, 1, 265
DOI: 10.1039/C8NA00012C

A rhodamine-6G-based “turn-on” fluorescent probe for selective detection of Fe3+ in living cells
Quanping Diao, Hua Guo, Zhiwei Yang, Weiwei Luo, Tiechun Li and Dongyan Hou
Anal. Methods, 2019, 11, 794
DOI: 10.1039/C8AY02659A

Unusual phosphine oxidation: new triazolopyridyl-quinolyl phosphine oxide fluorescent dyes
R. Ballesteros-Garrido, B. Abarca, R. Ballesteros, F. Colobert, F. R. Leroux and E. García-España
RSC Adv., 2015, 5, 29809
DOI: 10.1039/C5RA04386G

Fluorescent probes for the selective detection of chemical species inside mitochondria
Zheng Xu and Lin Xu
Chem. Commun., 2016, 52, 1094
DOI: 10.1039/C5CC09248E

A smart luminescent metal–organic framework-based logic system for simultaneous analysis of copper ions and hydrogen sulfide
Yufang Shu, Ji-Na Hao, Dechao Niu and Yongsheng Li
J. Mater. Chem. C, 2020, 8, 8635
DOI: 10.1039/D0TC00698J

The role of metals in mammalian olfaction of low molecular weight organosulfur compounds
Eric Block, Victor S. Batista, Hiroaki Matsunami, Hanyi Zhuang and Lucky Ahmed
Nat. Prod. Rep., 2017, 34, 529
DOI: 10.1039/C7NP00016B

A rhodamine based near-infrared fluorescent probe for selective detection of Cu2+ ions and its applications in bioimaging
Zhijian Chang, Shumeng Li, Jia-Hai Ye, Fuyan Lin, Yuncong Chen, Zijian Guo and Xuedong Gong
Anal. Methods, 2025, 17, 178
DOI: 10.1039/D4AY01922A

A theranostic abscisic acid-based molecular glue
Jing Chen, Huong T. X. Nguyen, Ming Yang, Fangxun Zeng, Hang Xu, Fu-Sen Liang and Wei Wang
Chem. Sci., 2023, 14, 3377
DOI: 10.1039/D2SC06995D

AIE active triphenylamine–benzothiazole based motifs: ESIPT or ICT emission
Vikas S. Padalkar, Daisuke Sakamaki, Kenji Kuwada, Norimitsu Tohnai, Tomoyuki Akutagawa, Ken-ichi Sakai and Shu Seki
RSC Adv., 2016, 6, 26941
DOI: 10.1039/C6RA02417C

Novel anthracene- and pyridine-containing Schiff base probe for selective “off–on” fluorescent determination of Cu2+ ions towards live cell application
Turibius Simon, Muthaiah Shellaiah, Venkatesan Srinivasadesikan, Ching-Chang Lin, Fu-Hsiang Ko, Kien Wen Sun and Ming-Chang Lin
New J. Chem., 2016, 40, 6101
DOI: 10.1039/C5NJ03168K

Anion-directed structural tuning of two azomethine-derived Zn2+ complexes with optoelectronic recognition of Cu2+ in aqueous medium with anti-cancer activities: from micromolar to femtomolar sensitivity with DFT revelation
Nithun Ranjan Pandit, Sourav Bej, Riyanka Das, Nirajan Ghosal, Ananya Mondal, Ranjana Pal, Meenakshi Ghosh, Priyabrata Banerjee and Biplab Biswas
Dalton Trans., 2023, 52, 11130
DOI: 10.1039/D3DT01901B

Perylene diimide-based organic π-motif for differentiating CN− and F− ions by electron-transfer and desilylation mechanisms: applications to complex logic circuits
Prabhpreet Singh, Lalit Singh Mittal, Harminder Singh, Gaurav Bhargava and Subodh Kumar
New J. Chem., 2017, 41, 10281
DOI: 10.1039/C7NJ02380D

Fluorescent probe for Cu2+ and the secondary application of the resultant complex to detect cysteine
Meipan Yang, Lifeng Ma, Jing Li and Longli Kang
RSC Adv., 2019, 9, 16812
DOI: 10.1039/C9RA02360G

A water-soluble bithiophene with increased photoluminescence efficiency and metal recognition ability
Estefanía Delgado-Pinar, Marta Pineiro and J. Sérgio Seixas de Melo
Dalton Trans., 2020, 49, 12319
DOI: 10.1039/D0DT01385D

N2S2 pyridinophane-based fluorescent chemosensors for selective optical detection of Cd2+ in soils
Alessandra Garau, Larisa Lvova, Eleonora Macedi, Gianluca Ambrosi, M. Carla Aragoni, Massimiliano Arca, Claudia Caltagirone, Simon J. Coles, Mauro Formica, Vieri Fusi, Luca Giorgi, Francesco Isaia, Vito Lippolis, James B. Orton and Roberto Paolesse
New J. Chem., 2020, 44, 20834
DOI: 10.1039/D0NJ03858J

Imidazole/benzimidazole-modified cyclotriphosphazenes as highly selective fluorescent probes for Cu2+: synthesis, configurational isomers, and crystal structures
Aylin Uslu, Süreyya Oğuz Tümay, Ahmet Şenocak, Fatma Yuksel, Elif Özcan and Serkan Yeşilot
Dalton Trans., 2017, 46, 9140
DOI: 10.1039/C7DT01134B

A new Schiff-base chemosensor for selective detection of Cu2+ and Co2+ and its copper complex for colorimetric sensing of S2− in aqueous solution
Min Seon Kim, Seong Youl Lee, Jae Min Jung and Cheal Kim
Photochem Photobiol Sci, 2017, 16, 1677
DOI: 10.1039/c7pp00229g

Recent progress on synthetic and protein-based genetically encoded sensors for fluorimetric Cu(i) recognition: binding and reaction-based approaches
Sushil Kumar, Jolly Kaushal, Tapas Goswami, Pankaj Kumar and Pramod Kumar
Sens. Diagn., 2022, 1, 429
DOI: 10.1039/D1SD00065A

Internally diketopyrrolopyrrole-bridged bis-anthracene macrocycle: a multifunctional fluorescent platform
Huan Zhou, Yuxuan Zhang, Zhiye Zheng, Junhua Wan, Hui Zhang, Kunhua Lin, Jonathan L. Sessler and Hongyu Wang
Chem. Sci., 2025, 16, 910
DOI: 10.1039/D4SC06067A

Networking switches for smart functions using copper signaling and dynamic heteroleptic complexation
Michael Schmittel
Dalton Trans., 2018, 47, 6654
DOI: 10.1039/C8DT01010B

A highly efficient aggregation-induced emission fluorescent sensor for copper(ii) in aqueous media
Dongmi Li, Juanjuan Li, Ying Duan, Bangtun Zhao and Baoming Ji
Anal. Methods, 2016, 8, 6013
DOI: 10.1039/C6AY01300G

A ratiometric fluorescent sensor for the mitochondrial copper pool
Clara Shen, Jacek L. Kolanowski, Carmen M.-N. Tran, Amandeep Kaur, Mia C. Akerfeldt, Matthew S. Rahme, Trevor W. Hambley and Elizabeth J. New
Metallomics, 2016, 8, 915
DOI: 10.1039/C6MT00083E

Cu2+selective chelators relieve copper-induced oxidative stressin vivo
Ananya Rakshit, Kaustav Khatua, Vinit Shanbhag, Peter Comba and Ankona Datta
Chem. Sci., 2018, 9, 7916
DOI: 10.1039/C8SC04041A

Influence of amino acid sequence in a peptidic Cu+-responsive luminescent probe inspired by the copper chaperone CusF
A. Roux, M. Isaac, V. Chabert, S. A. Denisov, N. D. McClenaghan and O. Sénèque
Org. Biomol. Chem., 2018, 16, 5626
DOI: 10.1039/C8OB01044G

Intramolecular substitution uncages fluorogenic probes for detection of metallo-carbapenemase-expressing bacteria
Aiguo Song, Yunfeng Cheng, Jinghang Xie, Niaz Banaei and Jianghong Rao
Chem. Sci., 2017, 8, 7669
DOI: 10.1039/C7SC02416A

An overview of Schiff base-based fluorescent turn-on probes: a potential candidate for tracking live cell imaging of biologically active metal ions
A. Afrin, Anjitha Jayaraj, M. S. Gayathri and Chinna Ayya Swamy P.
Sens. Diagn., 2023, 2, 988
DOI: 10.1039/D3SD00110E

A novel hexahydroquinazolin-2-amine-based fluorescence sensor for Cu2+ from isolongifolanone and its biological applications
Zhonglong Wang, Jinlai Yang, Yiqin Yang, Hua Fang, Xu Xu, Jian Rui, Fan Su, Haijun Xu and Shifa Wang
RSC Adv., 2017, 7, 33263
DOI: 10.1039/C7RA04484D

β-Cyclodextrin included coumarin derivatives as selective fluorescent sensors for Cu2+ ions in HeLa cells
Raihana Imran Khan and Kasi Pitchumani
RSC Adv., 2016, 6, 20269
DOI: 10.1039/C6RA01522K

Coordination geometry-induced optical imaging of l-cysteine in cancer cells using imidazopyridine-based copper(ii) complexes
Selvarasu Priyanga, Themmila Khamrang, Marappan Velusamy, Sellamuthu Karthi, Balasubramaniem Ashokkumar and Ramasamy Mayilmurugan
Dalton Trans., 2019, 48, 1489
DOI: 10.1039/C8DT04634D

Synthesis of organosilocane allied N-heteroaryl Schiff base chemosensor for the detection of Cu2+ metal ions and their biological applications
Gurjaspreet Singh, Shilpy, Akshpreet Singh, Diksha, Pawan, Suman, Cristóbal Espinosa-Ruíz, Maria Angeles Esteban and K. N. Singh
New J. Chem., 2020, 44, 13542
DOI: 10.1039/D0NJ01774D

A ratiometric, fluorescent BODIPY-based probe for transition and heavy metal ions
Wenwu Qin, Wei Dou, Volker Leen, Wim Dehaen, Mark Van der Auweraer and Noël Boens
RSC Adv., 2016, 6, 7806
DOI: 10.1039/C5RA23751C

AIE active fluorescent organic nanoparticles based optical detection of Cu2+ ions in pure water: a case of aggregation–disaggregation reversibility
Subhajit Saha, Suvendu Paul, Rakesh Debnath, Nilanjan Dey and Bhaskar Biswas
Anal. Methods, 2024, 16, 1058
DOI: 10.1039/D3AY02070C

A Zn-MOF functionalized with alkyne groups: ultrasensitive detection of Cu+ and Pd2+ ions in aqueous medium
Aashish, Ruchika Gupta and Rajeev Gupta
Sens. Diagn., 2023, 2, 1585
DOI: 10.1039/D3SD00188A

Synthetic ratiometric fluorescent probes for detection of ions
Sang-Hyun Park, Nahyun Kwon, Jee-Hyeon Lee, Juyoung Yoon and Injae Shin
Chem. Soc. Rev., 2020, 49, 143
DOI: 10.1039/C9CS00243J

Transition metal ions and neurotransmitters: coordination chemistry and implications for neurodegeneration
Jeasang Yoo, Jiyeon Han and Mi Hee Lim
RSC Chem. Biol., 2023, 4, 548
DOI: 10.1039/D3CB00052D

Selective binding and fluorescence sensing of Zn(ii)/Cd(ii) using macrocyclic tetra-amines with different fluorophores: insights into the design of selective chemosensors for transition metals
Giammarco Maria Romano, Yschtar Tecla Simonini Steiner, Francesco Bartoli, Luca Conti, Eleonora Macedi, Carla Bazzicalupi, Patrizia Rossi, Paola Paoli, Massimo Innocenti, Andrea Bencini and Matteo Savastano
Dalton Trans., 2025, 54, 1689
DOI: 10.1039/D4DT02415J

One-step microwave synthesis of carbon dots for highly sensitive and selective detection of copper ions in aqueous solution
Qiaoling Liu, Nan Zhang, Haoying Shi, Wenyan Ji, Xiaoqian Guo, Wen Yuan and Qin Hu
New J. Chem., 2018, 42, 3097
DOI: 10.1039/C7NJ05000C

A 1,8-naphthalimide-based chemosensor for dual-mode sensing: colorimetric and fluorometric detection of multiple analytes
Yeo-Kyung La, Jong-Ah Hong, Yujin Jeong and Jiyoun Lee
RSC Adv., 2016, 6, 84098
DOI: 10.1039/C6RA20100H

A simple indicator displacement assay ensemble for rapid and selective determination and naked-eye detection of Cu 2+ and citrate through a novel diazo-based colorimetric chemosensor
Hossein Tavallali, Abolfath Parhami, Fatemeh Ghasemi and Mohammad Ali Karimi
International Journal of Environmental Analytical Chemistry, 2025, 105, 1392
DOI: 10.1080/03067319.2023.2289637

A turn on fluorescent sensor for detecting Al3+ and colorimetric detection for Cu2+: Synthesis, cytotoxicity and on-site assay kit
Nur Amira Solehah Pungut, Hazwani Mat Saad, Kae Shin Sim and Kong Wai Tan
Journal of Photochemistry and Photobiology A: Chemistry, 2021, 414, 113290
DOI: 10.1016/j.jphotochem.2021.113290

Red and Near-Infrared Fluorescent Probe for Distinguishing Cysteine and Homocysteine through Single-Wavelength Excitation with Distinctly Dual Emissions
Taiyu Guo, Xinyue Chen, Wangbo Qu, Bin Yang, Ruowei Tian, Zhirong Geng and Zhilin Wang
Anal. Chem., 2022, 94, 5006
DOI: 10.1021/acs.analchem.1c04895

Terpyridyl appended poly(metaphenylene-alt-fluorene) π-conjugated fluorescent polymers: Highly selective and sensitive turn off probes for the detection of Cu2+
Amit Sil, Sk Najmul Islam and Sanjib K. Patra
Sensors and Actuators B: Chemical, 2018, 254, 618
DOI: 10.1016/j.snb.2017.07.067

Switching on the Fluorescence Emission of Polypyridine Ligands by Simultaneous Zinc(II) Binding and Protonation
Luca Conti, Claudia Giorgi, Barbara Valtancoli, Paola Paoli, Patrizia Rossi, Andrea Marchionni, Enrico Faggi and Andrea Bencini
ChemPlusChem, 2020, 85, 659
DOI: 10.1002/cplu.201900752

All‐in‐One Zinc‐Doped Prussian Blue Nanozyme for Efficient Capture, Separation, and Detection of Copper Ion (Cu2+) in Complicated Matrixes
Ying Zhang, Xue Yuan, Xinyue Guo, Huan Xu, Dongxin Zhang, Zhengyan Wu and Jia Zhang
Small, 2024, 20
DOI: 10.1002/smll.202306961

Responsive fluorescence enhancement for in vivo Cu(II) monitoring in zebrafish larvae
Hsiu-Chung Tu, Hsing-Yin Chen, Chang-Yi Wu and Po-Chiao Lin
Biosensors and Bioelectronics, 2022, 200, 113885
DOI: 10.1016/j.bios.2021.113885

A near-infrared fluorescent probe with thiadiazole unit as key skeleton for ICT and ESIPT mechanism and effective detection of Cu2+
Changyue Deng, Yongchen Wang, Yu Sun and Chengwei Lü
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 318, 124465
DOI: 10.1016/j.saa.2024.124465

Synthesis and application of highly sensitive fluorescent probe for Hg 2+ regulated by sulfur
Siyue Ma, Linyang Li, Mengyao She, Yan Mo, Shengyong Zhang, Ping Liu and Jianli Li
Chinese Chemical Letters, 2017, 28, 2014
DOI: 10.1016/j.cclet.2017.09.027

11B NMR/MRI Sensing of Copper(II) Ions In Vitro by the Decomposition of a Hybrid Compound of a nido‐o‐Carborane and a Metal Chelator
Tomohiro Tanaka, Rikita Araki, Takaomi Saido, Ryo Abe and Shin Aoki
Eur J Inorg Chem, 2016, 2016, 3330
DOI: 10.1002/ejic.201600346

Theoretical design of AK1 fluorescent probe via molecular engineering: enhancing Cu2+ selectivity and fluorescence lifetime
Zongyao Zhang, Yulin Zhou, Yan Jiang, Zhengdao Li, Yuxin Wang, Yu Wang and Jianbao Wu
Computational and Theoretical Chemistry, 2026, 1256, 115637
DOI: 10.1016/j.comptc.2025.115637

Incorporation of Rhodamine into a Host Polymer via In-Situ Generated Isocyanato Group and Application for the Detection of Cu2+ Ion
Sai Zhang, Zhe Yao, Wenqiang Qiao and Zhi Yuan Wang
Crystals, 2022, 12, 841
DOI: 10.3390/cryst12060841

BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing
Tiffany Tsang, Xingxing Gu, Caroline I. Davis, Jessica M. Posimo, Zoey A. Miller and Donita C. Brady
Molecular Cancer Research, 2022, 20, 1096
DOI: 10.1158/1541-7786.MCR-21-0250

A xanthene-based near-infrared fluorogenic probe for imaging Cu+ and assessing ionophores in 4T1 tumor-bearing mice
Yong-Xiang Hong, Liyun Ye, Ying Long, Fenglin Wang and Jian-Hui Jiang
Sensors and Actuators B: Chemical, 2024, 413, 135853
DOI: 10.1016/j.snb.2024.135853

Dissecting copper biology and cancer treatment: ‘Activating Cuproptosis or suppressing Cuproplasia’
Ying Yang, Man Li, Gang Chen, Suyi Liu, Houqi Guo, Xiongwei Dong, Kai Wang, Hongen Geng, Jun Jiang and Xiang Li
Coordination Chemistry Reviews, 2023, 495, 215395
DOI: 10.1016/j.ccr.2023.215395

A novel fluorescent and colorimetric dual-signals peptide-based probe for multianalyte detection and its multiple applications in real sample, bioimaging, test strip, logic gate, smartphone and food spoilage determination
Shiyang Li, Chunmei Pu, Xinlin Cao, Mengying Jia, Peng Wang and Jiang Wu
Journal of Molecular Structure, 2026, 1350, 144113
DOI: 10.1016/j.molstruc.2025.144113

Ferrocenyl pyrazoline–based gelator for detecting Cu2+ in aqueous solutions
Ying-Peng Zhang, Tian-Hang Wei, Yu-Chen Zhao, Yun-Shang Yang, Hui-Chen Guo and Hong-Rui Zhang
Colloid Polym Sci, 2023, 301, 1365
DOI: 10.1007/s00396-023-05153-7

Bioinspired fluorescent dihydroxyindoles oligomers
Zhan Li, Tianyou Wang, Fang Zhu, Zhao Wang and Yiwen Li
Chinese Chemical Letters, 2020, 31, 783
DOI: 10.1016/j.cclet.2019.05.021

Tracking mitochondrial Cu(I) fluctuations through a ratiometric fluorescent probe in AD model cells: Towards understanding how AβOs induce mitochondrial Cu(I) dyshomeostasis
Qiaowen Zhao, Liyi Ma, Siwei Chen, Lushan Huang, Guangwei She, Yongan Sun, Wensheng Shi and Lixuan Mu
Talanta, 2024, 271, 125716
DOI: 10.1016/j.talanta.2024.125716

A simple, reversible, colorimetric and water-soluble fluorescent chemosensor for the naked-eye detection of Cu2+ in ~ 100% aqueous media and application to real samples
Tao Sun, Qingfen Niu, Tianduo Li, Zongrang Guo and Haixia Liu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 188, 411
DOI: 10.1016/j.saa.2017.07.038

Implanted Nanosensors in Marine Organisms for Physiological Biologging: Design, Feasibility, and Species Variability
Michael A. Lee, Freddy T. Nguyen, Kathleen Scott, Nathan Y.L. Chan, Naveed Ali Bakh, Kelvin K. Jones, Crystal Pham, Pablo Garcia-Salinas, Daniel Garcia-Parraga, Andreas Fahlman, Vicente Marco, Volodymyr B. Koman, Ronald J. Oliver, Lloyd W. Hopkins, Consuelo Rubio, Rory P. Wilson, Mark G. Meekan, Carlos M. Duarte and Michael S. Strano
ACS Sens., 2019, 4, 32
DOI: 10.1021/acssensors.8b00538

Designing small-molecule and macromolecule sensors for imaging redox-active transition metal signaling
Aidan T. Pezacki, Jiaying Gao and Christopher J. Chang
Current Opinion in Chemical Biology, 2024, 83, 102541
DOI: 10.1016/j.cbpa.2024.102541

Development of a Low-Cost, Sensitivity-Optimized Fluorescence Sensor for Visible Spectrum Analysis
Zekun Wu, Scott E. Crawford, Michael P. Buric, Zach Splain and Kevin P. Chen
IEEE Sensors J., 2023, 23, 11574
DOI: 10.1109/JSEN.2023.3266422

Dihydroquinazolinone based “turn-off” fluorescence sensor for detection of Cu 2+ ions
Pravin N. Borase, Pranila B. Thale and Ganapati S. Shankarling
Dyes and Pigments, 2016, 134, 276
DOI: 10.1016/j.dyepig.2016.07.025

Copper signaling in the brain and beyond
Cheri M. Ackerman and Christopher J. Chang
Journal of Biological Chemistry, 2018, 293, 4628
DOI: 10.1074/jbc.R117.000176

Carbazole–azine based fluorescence ‘off–on’ sensor for selective detection of Cu2+ and its live cell imaging
Denzil Britto Christopher Leslee, Sekar Karuppannan, Karmegam Muthu Vengaian, Sivaraman Gandhi and Singaravadivel Subramanian
Luminescence, 2017, 32, 1354
DOI: 10.1002/bio.3332

Bioinorganic Platforms for Sensing, Biomimicry, and Energy Catalysis
Fung Man Ngo and Edmund C. M. Tse
Chem. Lett., 2021, 50, 974
DOI: 10.1246/cl.200875

Methylene Spacer Mediated Detection Switch Between Copper and Zinc Ions by Two Coumarin‐Pyrene Based Chemosensors
Devender Singh, Annan Ibrahim, Pramod Kumar and Rajeev Gupta
ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202202574

A novel colorimetric/fluorometric dual-channel sensor based on phenolphthalein and Bodipy for Sn (II) and Al (III) ions in half-aqueous medium and its applications in bioimaging
Alev Gul, Mehmet Oguz, Ahmed Nuri Kursunlu and Mustafa Yilmaz
Dyes and Pigments, 2020, 176, 108221
DOI: 10.1016/j.dyepig.2020.108221

Synthesis and crystal structure of the new copper(II) coordination polymer with N1-(2-сarboxyphenyl)-N2-(4-ethylcarboxyphenyl)oxalamide ligand
Vakhid A. Mamedov, Vera L. Mamedova, Victor V. Syakaev, Temur A. Kushatov, Dmitry E. Korshin, Il'dar Kh Rizvanov and Aidar T. Gubaidullin
Tetrahedron, 2024, 150, 133751
DOI: 10.1016/j.tet.2023.133751

Activatable Small‐Molecule Photoacoustic Probes that Cross the Blood–Brain Barrier for Visualization of Copper(II) in Mice with Alzheimer's Disease
Shichao Wang, Zonghai Sheng, Zhenguo Yang, Dehong Hu, Xiaojing Long, Gang Feng, Yubin Liu, Zhen Yuan, Jingjing Zhang, Hairong Zheng and Xuanjun Zhang
Angew Chem Int Ed, 2019, 58, 12415
DOI: 10.1002/anie.201904047

Fluorogenic Detection of Sulfite in Water by Using Copper(II) Azacyclam Complexes
Carlo Ciarrocchi, Donatella Sacchi, Massimo Boiocchi, Maduka Lankani Weththimuni, Alessio Orbelli Biroli and Maurizio Licchelli
Molecules, 2022, 27, 1852
DOI: 10.3390/molecules27061852

Developing fluorescence-improved fluoran dyes and applying for a copper selective and sensitive fluorescent probe and cell imaging
Kun Huang, Liangyu He, Xuanlin Yu, Bingxin Du, Dasheng Zheng and Lijuan Liang
Dyes and Pigments, 2023, 219, 111624
DOI: 10.1016/j.dyepig.2023.111624

Synthesis and living cell imaging of a novel fluorescent sensor for selective cupric detection
Qianping Luo, Koteswara Rao Bandi, Yanqiu Dong, Hongli Bao, Daliang Li and Qi Chen
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 214, 146
DOI: 10.1016/j.saa.2019.02.013

Precursor Ion Scan Mode-Based Strategy for Fast Screening of Polyether Ionophores by Copper-Induced Gas-Phase Radical Fragmentation Reactions
Eduardo J. Crevelin, Bruna Possato, João L. C. Lopes, Norberto P. Lopes and Antônio E. M. Crotti
Anal. Chem., 2017, 89, 3929
DOI: 10.1021/acs.analchem.6b02855

Triphenylamine Derived Radical Cations for Colorimetric Cu2+ Sensors and as an Antibacterial Agent
Luqi He, Jiao Tan, Chun Liu, Shouting Wu, Qi‐Long Zhang, Carl Redshaw and Xin‐Long Ni
ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202201155

Fluorescent Cu2+ sensor based on phenanthroline-BODIPY conjugate: A mechanistic study
Sudip Gorai, Ayan Ghosh, Saikat Chakraborty, Pascal Retailleau, Tapan K. Ghanty, Birija Sankar Patro and Soumyaditya Mula
Dyes and Pigments, 2022, 203, 110343
DOI: 10.1016/j.dyepig.2022.110343

Novel benzothiazole-based fluorescent probe for efficient detection of Cu2+/S2− and Zn2+ and its applicability in cell imaging
Linxiu Zhao, Junli Shi, Yongzheng Liu, Mingfeng Han, Shengling Li and Duanlin Cao
Analytica Chimica Acta, 2024, 1324, 343093
DOI: 10.1016/j.aca.2024.343093

A novel fluorescent and colorimetric dual-signals peptide-based probe for sequential recognition of Cu(II) and cimetidine and its multi-functional applications
Maoyue Zheng, Miao Zhou, Peng Wang and Yong An
Microchemical Journal, 2024, 198, 110159
DOI: 10.1016/j.microc.2024.110159

Two thiazole-fused fluoran-based fluorescent probes for selective and sensitive sensing copper ions and cell imaging application
Yaqing Zhang, Xuanlin Yu, Leyi Xu, Kun Huang, Bingxin Du and Lijuan Liang
Journal of Molecular Structure, 2024, 1303, 137551
DOI: 10.1016/j.molstruc.2024.137551

Recent developments on optical and electrochemical sensing of copper(II) ion based on transition metal complexes
Arumugam Ramdass, Veerasamy Sathish, Eththilu Babu, Murugesan Velayudham, Pounraj Thanasekaran and Seenivasan Rajagopal
Coordination Chemistry Reviews, 2017, 343, 278
DOI: 10.1016/j.ccr.2017.06.002

Green synthesis of highly fluorescent carbon quantum dots from almond resin for advanced theranostics in biomedical applications
P K Praseetha, R. I. Jari Litany, Hanan M. Alharbi, Alaa A. Khojah, Shopnil Akash, Mohammed Bourhia, Atrsaw Asrat Mengistie and Gamal A. Shazly
Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-75333-0

A simple colorimetric chemosensor for relay detection of Cu2+and S2−in aqueous solution
Min Seon Kim, Jae Min Jung, Hye Mi Ahn and Cheal Kim
Journal of Coordination Chemistry, 2018, 71, 355
DOI: 10.1080/00958972.2017.1420787

A Copper‐Incorporated meso‐(N’‐acetyl‐hydrizide)‐BODIPY as a “Off‐On” Fluorescent Probe for Histidine
Siyoung Cho, Pooja Sharma, Rizki Rachmad Saputra and Youngmi Kim
Chemistry — An Asian Journal, 2025, 20
DOI: 10.1002/asia.202401182

A low cytotoxic and sensitive NIR probe for the “on-off” fluorescence detection of Cu2+ and imaging in living cells and animals
Pan Pan, Dai Zeng, Jinping Wu, Jiaxing Lu, Aiping Xing, Yaoyao Yuan, Bin Zhang, Yuxin Zhang, Suiqing Chen and Juan Yuan
Journal of Molecular Structure, 2025, 1328, 141300
DOI: 10.1016/j.molstruc.2024.141300

Cu + -specific CopB transporter: Revising P 1B -type ATPase classification
Rahul Purohit, Matthew O. Ross, Sharon Batelu, April Kusowski, Timothy L. Stemmler, Brian M. Hoffman and Amy C. Rosenzweig
Proc. Natl. Acad. Sci. U.S.A., 2018, 115, 2108
DOI: 10.1073/pnas.1721783115

Ultrasensitive fluorescent probe for copper ion based on cadmium selenide/cadmium sulfide quantum dots capped with dimercaprol
Qin Zhao, Guanhong Tao, Cunwang Ge, Yan Cai, Qicheng Qiao and Xueping Jia
Spectroscopy Letters, 2018, 51, 216
DOI: 10.1080/00387010.2018.1452266

Polyacrylonitrile fluorescent nanofibers for selective and reversible copper detection in aqueous solutions
Xianhang Yan, Yanxin Wang, Bingyang Li, Zhenzhen Huang, Zhiyuan Gao, Xinhui Mao, Wei Wang, Zhijun Zhu, Matt J. Kipper, Linjun Huang and Jianguo Tang
Applied Surface Science, 2022, 602, 154302
DOI: 10.1016/j.apsusc.2022.154302

Aza‐ and Mixed Thia/Aza‐Macrocyclic Receptors with Quinoline‐Bearing Pendant Arms for Optical Discrimination of Zinc(II) or Cadmium(II) Ions
Alessandra Garau, M. Carla Aragoni, Massimiliano Arca, Andrea Bencini, Alexander J. Blake, Claudia Caltagirone, Claudia Giorgi, Vito Lippolis and Mariano Andrea Scorciapino
ChemPlusChem, 2020, 85, 1789
DOI: 10.1002/cplu.202000444

Highly Sensitive and Selective Copper (II)-Catalyzed Dual-DNAzyme Colorimetric Biosensor Based on Exonuclease III-Mediated Cyclical Assembly
Baiqiang Zhai, Kunlun Huang, Hongtao Wang, Dongmin Su and Yuancong Xu
Catalysts, 2021, 11, 1352
DOI: 10.3390/catal11111352

Unveiling versatile properties of a N,N′-bis(biphenyl)amino tailored stilbene-terpyridyl conjugate and its multifunctional role in fluorescence sensing
Amit Sil, Suman Dolai, Chhanda Mondal and Sanjib K. Patra
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 343, 126595
DOI: 10.1016/j.saa.2025.126595

Fluorescent detection of Zn(II) and In(III) and colorimetric detection of Cu(II) and Co(II) by a versatile chemosensor
Ahran Kim, Ji Hye Kang, Hyo Jung Jang and Cheal Kim
Journal of Industrial and Engineering Chemistry, 2018, 65, 290
DOI: 10.1016/j.jiec.2018.04.040

A Highly Sensitive and Selective Fluorescein-Based Cu2+ Probe and Its Bioimaging in Cell
Xin Leng, Mengyao She, Xilang Jin, Jiao Chen, Xuehao Ma, Fulin Chen, Jianli Li and Bingqin Yang
Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.932826

Ratiometric fluorescent sensing of copper ion based on chromaticity change strategy
Hongmei Li, Xuefeng Wang, Zheng Cai, Ling Lu, Jia Tao, Bin Sun, Yuanyuan Yang, Quan Xu, Zhiqiang Yu and Peng Zhao
Anal Bioanal Chem, 2017, 409, 6655
DOI: 10.1007/s00216-017-0621-2

A Fluoran-Based Cu2+-Selective Fluorescent Probe and its Application in Cell Imaging
Qi Qiu, Bo Yu, Kun Huang and Dabin Qin
J Fluoresc, 2020, 30, 859
DOI: 10.1007/s10895-020-02551-w

In situ and real-time imaging of superoxide anion and peroxynitrite elucidating arginase 1 nitration aggravating hepatic ischemia-reperfusion injury
Wen Zhang, Jihong Liu, Ping Li, Xin Wang, Simin Bi, Jiao Zhang, Wei Zhang, Hui Wang and Bo Tang
Biomaterials, 2019, 225, 119499
DOI: 10.1016/j.biomaterials.2019.119499

An Alkyne-Directed Cleavage Approach for Activity-Based Cu(I) Sensing Reveals Manganese-Promoted Sensitization of Cuproptosis
Xiao Xie, Gen Li, Aidan T. Pezacki, Jiaying Gao, Miku Oi and Christopher J. Chang
J. Am. Chem. Soc., 2025, 147, 34564
DOI: 10.1021/jacs.5c09297

Homocysteine fluorescent probes: Sensing mechanisms and biological applications
Waqas Pervez, Laraib, Caixia Yin and Fangjun Huo
Coordination Chemistry Reviews, 2025, 522, 216202
DOI: 10.1016/j.ccr.2024.216202

Capturing copper to inhibit inflammation
Christopher J. Chang and Donita C. Brady
Nat Chem Biol, 2023, 19, 937
DOI: 10.1038/s41589-023-01383-6

Shining New Light on Biological Systems: Luminescent Transition Metal Complexes for Bioimaging and Biosensing Applications
Lawrence Cho-Cheung Lee and Kenneth Kam-Wing Lo
Chem. Rev., 2024, 124, 8825
DOI: 10.1021/acs.chemrev.3c00629

Purine‐Based Fluorescent Sensors for Imaging Zinc Ions in HeLa Cells
Pratibha, Swati Singh, Sri Sivakumar and Sandeep Verma
Eur J Inorg Chem, 2017, 2017, 4202
DOI: 10.1002/ejic.201700806

A dicyanomethylene-4H-pyran-based fluorescence probe with high selectivity and sensitivity for detecting copper (II) and its bioimaging in living cells and tissue
Zheng Li, Yanqi Xu, Huandi Xu, Mengyuan Cui, Tianguang Liu, Xiangyu Ren, Jianfei Sun, Dawei Deng, Yueqing Gu and Peng Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 244, 118819
DOI: 10.1016/j.saa.2020.118819

Thioether Coordination Chemistry for Molecular Imaging of Copper in Biological Systems
Karla M. Ramos‐Torres, Safacan Kolemen and Christopher J. Chang
Israel Journal of Chemistry, 2016, 56, 724
DOI: 10.1002/ijch.201600023

Advances in reaction-based synthetic fluorescent probes for studying the role of zinc and copper ions in living systems
Kensuke Okuda, Ippei Takashima and Akira Takagi
J. Clin. Biochem. Nutr., 2023, 72, 1
DOI: 10.3164/jcbn.22-92

Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system
Tong Xiao, Cheri M. Ackerman, Elizabeth C Carroll, Shang Jia, Adam Hoagland, Jefferson Chan, Bao Thai, Christine S. Liu, Ehud Y. Isacoff and Christopher J. Chang
Nat Chem Biol, 2018, 14, 655
DOI: 10.1038/s41589-018-0062-z

Fluorescent and electrochemical detection of Cu (II) ions in aqueous environment by a novel, simple and readily available AIE probe
Erman Karakuş, Simay Gunduz, Lokman Liv and Turan Ozturk
Journal of Photochemistry and Photobiology A: Chemistry, 2020, 400, 112702
DOI: 10.1016/j.jphotochem.2020.112702

Small molecule fluorescent probes of protein vicinal dithiols
Guodong Hu, Huiyi Jia, Lanning Zhao, Dong-Hyung Cho and Jianguo Fang
Chinese Chemical Letters, 2019, 30, 1704
DOI: 10.1016/j.cclet.2019.06.039

Triphenyl-imidazole based reversible coloro/fluorimetric sensing and electrochemical removal of Cu2+ ions using capacitive deionization and molecular logic gates
G. Prabakaran, K. Velmurugan, R. Vickram, C. Immanuel David, A. Thamilselvan, J. Prabhu and R. Nandhakumar
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246, 119018
DOI: 10.1016/j.saa.2020.119018

Ruthenium(II)‐Polypyridyl‐Based Sensor Bearing a DPA Unit for Selective Detection of Cu(II) Ion in Aqueous Medium
Aayushi Arora, Jolly Kaushal, Arun Kumar, Pramod Kumar and Sushil Kumar
ChemistrySelect, 2019, 4, 6140
DOI: 10.1002/slct.201900682

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
Sathidpak Nantasanti, Bart Spee, Hedwig S. Kruitwagen, Chen Chen, Niels Geijsen, Loes A. Oosterhoff, Monique E. van Wolferen, Nicolas Pelaez, Hille Fieten, Richard W. Wubbolts, Guy C. Grinwis, Jefferson Chan, Meritxell Huch, Robert R.G. Vries, Hans Clevers, Alain de Bruin, Jan Rothuizen, Louis C. Penning and Baukje A. Schotanus
Stem Cell Reports, 2015, 5, 895
DOI: 10.1016/j.stemcr.2015.09.002

DNAzyme‐Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells
Mengyi Xiong, Zhenglin Yang, Ryan J. Lake, Junjie Li, Shanni Hong, Huanhuan Fan, Xiao‐Bing Zhang and Yi Lu
Angew Chem Int Ed, 2020, 59, 1891
DOI: 10.1002/anie.201912514

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis
Yun Liao, Junjie Zhao, Katarzyna Bulek, Fangqiang Tang, Xing Chen, Gang Cai, Shang Jia, Paul L. Fox, Emina Huang, Theresa T. Pizarro, Matthew F. Kalady, Mark W. Jackson, Shideng Bao, Ganes C. Sen, George R. Stark, Christopher J. Chang and Xiaoxia Li
Nat Commun, 2020, 11
DOI: 10.1038/s41467-020-14698-y

Protonation of carboxyl groups in EuDOTA-tetraamide complexes results in catalytic prototropic exchange and quenching of the CEST signal
Lei Zhang, Osasere M. Evbuomwan, Michael Tieu, Piyu Zhao, Andre F. Martins and A. Dean Sherry
Phil. Trans. R. Soc. A., 2017, 375, 20170113
DOI: 10.1098/rsta.2017.0113

A novel approach to study the structure-property relationships and applications in living systems of modular Cu2+ fluorescent probes
Mengyao She, Zheng Yang, Likai Hao, Zhaohui Wang, Tianyou Luo, Martin Obst, Ping Liu, Yehua Shen, Shengyong Zhang and Jianli Li
Sci Rep, 2016, 6
DOI: 10.1038/srep28972

An Activity-Based Sensing Approach to Multiplex Mapping of Labile Copper Pools by Stimulated Raman Scattering
Yishu Jiang, Elsy El Khoury, Aidan T. Pezacki, Naixin Qian, Miku Oi, Laura Torrente, Sophia G. Miller, Martina Ralle, Gina M. DeNicola, Wei Min and Christopher J. Chang
J. Am. Chem. Soc., 2024, 146, 33324
DOI: 10.1021/jacs.4c06296

A kinetic model of copper homeostasis in Saccharomyces cerevisiae
Cade Dulaney, Jay R. Walton and Paul A. Lindahl
Journal of Biological Chemistry, 2025, 301, 110368
DOI: 10.1016/j.jbc.2025.110368

Computer-Assisted Design of Environmentally Friendly and Light-Stable Fluorescent Dyes for Textile Applications
Songsong Tang, Guoqiang Chen and Gang Sun
IJMS, 2019, 20, 5971
DOI: 10.3390/ijms20235971

Novel Bis-pyrazoline Fluorescent Probe for Cu2+ and Fe3+ Detection and Application in Cell Imaging
Yun-Shang Yang, Fu-Nian Wang, Ying-Peng Zhang, Feng Yang and Ji-Jun Xue
J Fluoresc, 2024, 34, 159
DOI: 10.1007/s10895-023-03213-3

Novel Furochromenone based Dual Channel Sensors for Selective Detection of Cu2+ with Potential Applications in Sample Monitoring, Membrane Sensing and Photo–printing
Manoj Kumar, Lokesh Kumar Kumawat, Vinod Kumar Gupta  and Anuj Sharma
ChemistrySelect, 2016, 1, 277
DOI: 10.1002/slct.201500023

Real-Time, Selective Detection of Copper(II) Using Ionophore-Grafted Carbon-Fiber Microelectrodes
Yuanyuan Yang, Ahmad A. Ibrahim, Parastoo Hashemi and Jennifer L. Stockdill
Anal. Chem., 2016, 88, 6962
DOI: 10.1021/acs.analchem.6b00825

Alkynylboration Reaction Leading to Boron-Containing π-Extended cis-Stilbenes as a Highly Tunable Fluorophore
Marina Nogami, Keiichi Hirano, Kensuke Morimoto, Masaru Tanioka, Kazunori Miyamoto, Atsuya Muranaka and Masanobu Uchiyama
Org. Lett., 2019, 21, 3392
DOI: 10.1021/acs.orglett.9b01132

A multifunctional Cu2+, Fe3+ and Co2+ selective fluorescent probe and its application in cell/marine medaka (Oryzias melastigma) imaging
Chunwei Yu, Mei Yang, Haoran Zhang, Xiangxiang Li and Jun Zhang
Journal of Molecular Structure, 2026, 1358, 145430
DOI: 10.1016/j.molstruc.2026.145430

Synthesis of a novel π-extended hybrid rhodamine dye with far-red fluorescence emission and its application in bioimaging
Kun Huang, Xiaojie Jiao, Chang Liu, Qing Wang, Xiaoying Qiu, Song He, Liancheng Zhao and Xianshun Zeng
Dyes and Pigments, 2017, 145, 561
DOI: 10.1016/j.dyepig.2017.06.047

A dual-function luminescent probe for copper(II) ions and pH detection based on ruthenium(II) complex
Mengting Xie, Jiecheng Zhao, Xufeng Mai, Yan Chen, Wei Zhao, Ming Sun, Lin Yu and Hui-Juan Yu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 277, 121265
DOI: 10.1016/j.saa.2022.121265

Design, synthesis and evaluate of imidazole, triazine and metastable oxazolone derivatives as chemosensor for detecting metals
Ayman M. Algohary and Mona H. Alhalafi
Journal of Saudi Chemical Society, 2022, 26, 101537
DOI: 10.1016/j.jscs.2022.101537

Host and Pathogen Copper-Transporting P-Type ATPases Function Antagonistically during Salmonella Infection
Erik Ladomersky, Aslam Khan, Vinit Shanbhag, Jennifer S. Cavet, Jefferson Chan, Gary A. Weisman, Michael J. Petris and Andreas J. Bäumler
Infect Immun, 2017, 85
DOI: 10.1128/IAI.00351-17

Synthesis and Application of 1,8-Naphthalimide Derivatives Fluorescent Probe for Sequential Recognition of Cu2+ and H2PO4−
Shukui Pang, Yanchao Yu, Wenju Wu, Mianyuan Wu, Jun You, Canyao Wu and Panru Zu
J Fluoresc, 2024, 35, 2685
DOI: 10.1007/s10895-024-03692-y

A tetraphenylethene-based Schiff base AIEgen with a large Stokes shift as probe for highly sensitive and selective detection of aqueous Cu2+ ions and its application in cell imaging
Jiakun Bai, Jiang Peng, Ting Xu, Ming Bu, Wei Chen, Yuanjun Nie and Junhui Jia
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 290, 122190
DOI: 10.1016/j.saa.2022.122190

Dynamic Photoacoustic Imaging of Mobile Cu(II) in Vivo via Catalytic Radical Cation Formation
Zhiyong Jiang, Qian Sun, Xiaoqing Wang, Yuncong Chen, Fang Liu, Jing Zhao, Zijian Guo and Zhipeng Liu
Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202500149

Synthesis of NIR fluorescent thienyl-containing aza-BODIPY and its application for detection of Hg2+: Electron transfer by bonding with Hg2+
Xin-Dong Jiang, Jiuli Zhao, Qian Li, Chang-Liang Sun, Jian Guan, Gao-Tao Sun and Lin-Jiu Xiao
Dyes and Pigments, 2016, 125, 136
DOI: 10.1016/j.dyepig.2015.09.023

A near-infrared turn-on fluorescent sensor for the determination of copper in mitochondria
Taiyu Guo, Ruowei Tian, Wangbo Qu, Bin Yang, Zhirong Geng and Zhilin Wang
Dyes and Pigments, 2022, 205, 110483
DOI: 10.1016/j.dyepig.2022.110483

Advances in the development of fluorescence probes for cell plasma membrane imaging
Chaolong Liu, Xiaona Gao, Jingli Yuan and Run Zhang
TrAC Trends in Analytical Chemistry, 2020, 133, 116092
DOI: 10.1016/j.trac.2020.116092

Recent Advance in Nucleus-Targeted Fluorescent Probes for Bioimaging, Detection and Therapy
Cong Hu, Shuai Xu, Zhiling Song, Haixia Li and Hongwen Liu
Chemosensors, 2023, 11, 125
DOI: 10.3390/chemosensors11020125

Revealing Single-Cell Heterogeneity of Labile Cu(I) Accumulation and Metabolism in Microalgae by Image-Enabled Flow Cytometry
Shaoxi Deng, Robert Z. Qi and Wen-Xiong Wang
Environ. Sci. Technol., 2026, 60, 3862
DOI: 10.1021/acs.est.5c13719

Origin of Water-Induced Fluorescence Turn-On from a Schiff Base Compound: AIE or H-Bonding Promoted ESIPT?
Lucas McDonald, Junfeng Wang, Nick Alexander, Hui Li, Tianbo Liu and Yi Pang
J. Phys. Chem. B, 2016, 120, 766
DOI: 10.1021/acs.jpcb.5b10909

A reverse-signal response fluorescence sensor based on NH2-MIL-101(Fe) and silicon-doped carbon quantum dots for selective determination of copper ions
Jingjing Chen, Zhixiang Li, Xiaoqi Li and Yingxiang Du
Journal of Photochemistry and Photobiology A: Chemistry, 2024, 452, 115579
DOI: 10.1016/j.jphotochem.2024.115579

[12]aneN 3 -based multifunctional compounds as fluorescent probes and nucleic acids delivering agents
Yong-Guang Gao, Shu-Yuan Huangfu, Suryaji Patil, Quan Tang, Wan Sun, Yu Li, Zhong-Lin Lu and Airong Qian
Drug Delivery, 2020, 27, 66
DOI: 10.1080/10717544.2019.1704943

A new dual-functional ratiometric fluorescent probe based on quinoline–triphenylamine schiff base for detecting copper and thorium in environmental samples
Shilpa Taneja, Selva Kumar Ramasamy and A. Mujthaba Aatif
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 348, 127194
DOI: 10.1016/j.saa.2025.127194

Tetraphenylpyrazine-Based Manganese Metal–Organic Framework as a Multifunctional Sensor for Cu2+, Cr3+, MnO4–, and 2,4,6-Trinitrophenol and the Construction of a Molecular Logical Gate
Yi Zou, Kun Huang, Xiangyu Zhang, Dabin Qin and Bin Zhao
Inorg. Chem., 2021, 60, 11222
DOI: 10.1021/acs.inorgchem.1c01226

Click Chemistry Reaction-Triggered 3D DNA Walking Machine for Sensitive Electrochemical Detection of Copper Ion
Min Qing, Shunbi Xie, Wei Cai, Dianyong Tang, Ying Tang, Jin Zhang and Ruo Yuan
Anal. Chem., 2018, 90, 11439
DOI: 10.1021/acs.analchem.8b02555

Asymmetric anthracene-fused BODIPY dye with large Stokes shift: Synthesis, photophysical properties and bioimaging
Liutao Yang, Ying Liu, Xiangge Zhou, Yujiao Wu, Chunping Ma, Wei Liu and Chun Zhang
Dyes and Pigments, 2016, 126, 232
DOI: 10.1016/j.dyepig.2015.11.028

A Highly Selective Mn(II)-Specific DNAzyme and Its Application in Intracellular Sensing
Huanhuan Fan, Claire E. McGhee, Ryan J. Lake, Zhenglin Yang, Zijian Guo, Xiao-Bing Zhang and Yi Lu
JACS Au, 2023, 3, 1615
DOI: 10.1021/jacsau.3c00062

Coumarin–pyrene conjugate: Synthesis, structure and Cu-selective fluorescent sensing in mammalian kidney cells
Manzoor Ahmad Wani, Pankaj Kumar Singh, Rampal Pandey and Mrituanjay D. Pandey
Journal of Luminescence, 2016, 171, 159
DOI: 10.1016/j.jlumin.2015.11.017

A water-soluble, small molecular fluorescence probe based on 2-(2′-hydroxyphenyl) benzoxazole for Zn2+ in plants
Yuting Shang, Shuwen Zheng, Madalitso Tsakama, Miao Wang and Weihua Chen
Tetrahedron Letters, 2018, 59, 4003
DOI: 10.1016/j.tetlet.2018.09.057

Small-Molecule Fluorescent Probes for Binding- and Activity-Based Sensing of Redox-Active Biological Metals
Karandeep Grover, Alla Koblova, Aidan T. Pezacki, Christopher J. Chang and Elizabeth J. New
Chem. Rev., 2024, 124, 5846
DOI: 10.1021/acs.chemrev.3c00819

Intracellularly manipulable aggregation of the aggregation-induced emission luminogens
Wen-Jin Wang, Zhuo-Yang Xin, Dan Liu, Qian Liu, Yong Liu, Zijie Qiu, Jianquan Zhang, Parvej Alam, Xu-Min Cai, Zheng Zhao and Ben Zhong Tang
Biosensors and Bioelectronics, 2025, 267, 116800
DOI: 10.1016/j.bios.2024.116800

Mitochondria-targeted smart AIEgens: Imaging and therapeutics
Haidong Li, Heejeong Kim, Cheng Zhang, Shuang Zeng, Qixian Chen, Lingyun Jia, Jingyun Wang, Xiaojun Peng and Juyoung Yoon
Coordination Chemistry Reviews, 2022, 473, 214818
DOI: 10.1016/j.ccr.2022.214818

DNAzyme‐Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells
Mengyi Xiong, Zhenglin Yang, Ryan J. Lake, Junjie Li, Shanni Hong, Huanhuan Fan, Xiao‐Bing Zhang and Yi Lu
Angewandte Chemie, 2020, 132, 1907
DOI: 10.1002/ange.201912514

Aktivitätsbasierte Sensorik: ein synthetisch‐methodischer Ansatz für die selektive molekulare Bildgebung und darüber hinaus.
Kevin J. Bruemmer, Steven W. M. Crossley and Christopher J. Chang
Angewandte Chemie, 2020, 132, 13838
DOI: 10.1002/ange.201909690

A quinoline-fluoran hybrid fluorescent probe for selectively and sensitively sensing copper ions and fluorescence imaging application
Bingxin Du, Qi Li, Kun Huang and Lijuan Liang
Journal of Molecular Structure, 2023, 1271, 134015
DOI: 10.1016/j.molstruc.2022.134015

Non-aromatic single amino acid, lysine: A simple fluorescence sensor for selective detection of Cu2+ and Co2+ with colorimetric distinction by the virtue of its self-aggregation behaviour
Revathy Sahadevan, Anna Jose, Mintu Porel and Sushabhan Sadhukhan
Journal of Photochemistry and Photobiology A: Chemistry, 2023, 445, 115086
DOI: 10.1016/j.jphotochem.2023.115086

AEE active Schiff base-bearing pyrene unit and further Cu2+–induced self-assembly process
Wei-Na Wu, Pan-Dong Mao, Yuan Wang, Xian-Jie Mao, Zhou-Qing Xu, Zhi-Hong Xu, Xiao-Lei Zhao, Yun-Chang Fan and Xu-Feng Hou
Sensors and Actuators B: Chemical, 2018, 258, 393
DOI: 10.1016/j.snb.2017.11.114

A pyrene-containing Schiff base fluorescent ratiometric probe for the detection of Cu2+ in aqueous solutions and in cells
Li-Jun Ma, Qingjian Liang, Ruihong Feng, Zu Lv, Fengchao Cui, Ligui Li, Liting Yang, Hong Liu and Fengqiang Sun
Journal of Photochemistry and Photobiology A: Chemistry, 2021, 408, 113086
DOI: 10.1016/j.jphotochem.2020.113086

The Intestinal Copper Exporter CUA-1 Is Required for Systemic Copper Homeostasis in Caenorhabditis elegans
Haarin Chun, Anuj Kumar Sharma, Jaekwon Lee, Jefferson Chan, Shang Jia and Byung-Eun Kim
Journal of Biological Chemistry, 2017, 292, 1
DOI: 10.1074/jbc.M116.760876

Copper transporters and copper chaperones: roles in cardiovascular physiology and disease
Tohru Fukai, Masuko Ushio-Fukai and Jack H. Kaplan
American Journal of Physiology-Cell Physiology, 2018, 315, C186
DOI: 10.1152/ajpcell.00132.2018

Cell-surface copper transporters and superoxide dismutase 1 are essential for outgrowth during fungal spore germination
Samuel Plante, Vincent Normant, Karla M. Ramos-Torres and Simon Labbé
Journal of Biological Chemistry, 2017, 292, 11896
DOI: 10.1074/jbc.M117.794677

Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels
Pengrong An, Zixin Zhang, Jincan Yang, Tianming Wang, Zhuoyue Wang, Chun-Lin Sun, Chuanguang Qin and Jun Li
Anal. Chem., 2023, 95, 13456
DOI: 10.1021/acs.analchem.3c01174

Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P-Glycoprotein Mediated Efflux
Karla M. Acevedo, David J. Hayne, Lachlan E. McInnes, Asif Noor, Clare Duncan, Diane Moujalled, Irene Volitakis, Angela Rigopoulos, Kevin J. Barnham, Victor L. Villemagne, Anthony R. White and Paul S. Donnelly
J. Med. Chem., 2018, 61, 711
DOI: 10.1021/acs.jmedchem.7b01158

Optical Fiber Sensors for Biocide Monitoring: Examples, Transduction Materials, and Prospects
Rui P. C. L. Sousa, Rita B. Figueira, Susana P. G. Costa and M. Manuela M. Raposo
ACS Sens., 2020, 5, 3678
DOI: 10.1021/acssensors.0c01615

A photo-reversible, sensitive, and selective sensor for copper ions in an aqueous medium
Arvind Kumar, Anupama Datta and Satish Kumar
Journal of Molecular Structure, 2022, 1260, 132807
DOI: 10.1016/j.molstruc.2022.132807

Recent Progress in Triazole Based Chromogenic and Fluorogenic Chemosensor for the Detection of Hg2+ Metal ion: A Review
Umme Salma, Md. Zafer Alam, Suhail Ahmad, Md. Mohasin and Salman A. Khan
J Fluoresc, 2025, 35, 10201
DOI: 10.1007/s10895-025-04269-z

An azine based sensor for selective detection of Cu2+ ions and its copper complex for sensing of phosphate ions in physiological conditions and in living cells
Karishma Tiwari, Sumit Kumar, Vipan Kumar, Jeevanjot Kaur, Saroj Arora and Rakesh Kumar Mahajan
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 191, 16
DOI: 10.1016/j.saa.2017.09.072

Stepwise Assembly of Turn‐on Fluorescence Sensors in Multicomponent Metal–Organic Frameworks for in Vitro Cyanide Detection
Jialuo Li, Shuai Yuan, Jun‐Sheng Qin, Jiandong Pang, Peng Zhang, Yingmu Zhang, Yanyan Huang, Hannah F. Drake, Wenshe R. Liu and Hong‐Cai Zhou
Angewandte Chemie, 2020, 132, 9405
DOI: 10.1002/ange.202000702

A water-soluble fluorescent probe derived from fish collagen peptides for multi-targeted detection of Cu2+ and Zn2+ ions via AIE and ESIPT mechanisms
Wenyu Guo, Yuanyuan Zhang, Yunxuan Wang, Zhijun Hu, Peixuan Xu, Jingying Cai, Peirong Yu, Shiya Chen, Lei Zhang, Benmei Wei, Juntao Zhang, Sheng Li, Haibo Wang and Lingyun Chen
Microchemical Journal, 2025, 215, 114313
DOI: 10.1016/j.microc.2025.114313

Extracellular Cu2+ pools and their detection: From current knowledge to next-generation probes
Enrico Falcone, Michael Okafor, Nicolas Vitale, Laurent Raibaut, Angélique Sour and Peter Faller
Coordination Chemistry Reviews, 2021, 433, 213727
DOI: 10.1016/j.ccr.2020.213727

Colorimetric Detection of Copper(II) Ions Using Schiff‐Base Derivatives
Ziya Aydin and Mustafa Keles
ChemistrySelect, 2020, 5, 7375
DOI: 10.1002/slct.202001041

Copper signalling: causes and consequences
Julianna Kardos, László Héja, Ágnes Simon, István Jablonkai, Richard Kovács and Katalin Jemnitz
Cell Commun Signal, 2018, 16
DOI: 10.1186/s12964-018-0277-3

Novel fluorescent probe bearing triarylimidazole and pyridine moieties for the rapid and naked-eye recognition of Cu 2+
Shuzhi Liu, Yijiang Liu, Hua Pan, Hongbiao Chen and Huaming Li
Tetrahedron Letters, 2018, 59, 108
DOI: 10.1016/j.tetlet.2017.11.059

Targeted cysteine and glutathione detection in extra/intracellular systems by copper-based fluorescent imaging probes
Thavasilingam Nagendraraj, Sakthivel Vishnu Priya, Jamespandi Annaraj and Suresh Sagadevan
Coordination Chemistry Reviews, 2023, 495, 215368
DOI: 10.1016/j.ccr.2023.215368

The Triple Roles of Glutathione for a DNA-Cleaving DNAzyme and Development of a Fluorescent Glutathione/Cu2+-Dependent DNAzyme Sensor for Detection of Cu2+ in Drinking Water
Shijin Wang, Chengcheng Liu, Guiying Li, Yongjie Sheng, Yanhong Sun, Hongyue Rui, Jin Zhang, Jiacui Xu and Dazhi Jiang
ACS Sens., 2017, 2, 364
DOI: 10.1021/acssensors.6b00667

Dual-ligand Zr-based metal–organic framework for ratiometric fluorescence sensing and imaging of copper ion in biological system
Xiuhua Wei, Xiaoxian Feng, Hui Dong, Yanli Zhou, Cuixia Ling, Yuanqiang Hao and Maotian Xu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 340, 126325
DOI: 10.1016/j.saa.2025.126325

Activatable Small‐Molecule Photoacoustic Probes that Cross the Blood–Brain Barrier for Visualization of Copper(II) in Mice with Alzheimer's Disease
Shichao Wang, Zonghai Sheng, Zhenguo Yang, Dehong Hu, Xiaojing Long, Gang Feng, Yubin Liu, Zhen Yuan, Jingjing Zhang, Hairong Zheng and Xuanjun Zhang
Angewandte Chemie, 2019, 131, 12545
DOI: 10.1002/ange.201904047

A simple triphenylamine based turn-off fluorescent sensor for copper (II) ion detection in semi-aqueous solutions
Dhanushkodi Mohanasundaram, R. Bhaskar, N. Lenin, Kasi Nehru, G. Rajagopal, Gujuluva Gangatharan Vinoth Kumar and Jegathalaprathaban Rajesh
Journal of Photochemistry and Photobiology A: Chemistry, 2022, 427, 113850
DOI: 10.1016/j.jphotochem.2022.113850

Selective Detection of Cu+ Ions in Live Cells via Fluorescence Lifetime Imaging Microscopy
Martin Priessner, Peter A. Summers, Benjamin W. Lewis, Magdalena Sastre, Liming Ying, Marina K. Kuimova and Ramon Vilar
Angewandte Chemie, 2021, 133, 23332
DOI: 10.1002/ange.202109349

A novel pyrazoline-based fluorescent probe for Cu2+ in aqueous solution and imaging in live cell
Ying-peng Zhang, Yu-chen Zhao, Qing-hua Xue, Yun-shang Yang, Hui-Chen Guo and Ji-Jun Xue
Inorganic Chemistry Communications, 2021, 129, 108612
DOI: 10.1016/j.inoche.2021.108612

Analytical Methods for Imaging Metals in Biology: From Transition Metal Metabolism to Transition Metal Signaling
Cheri M. Ackerman, Sumin Lee and Christopher J. Chang
Anal. Chem., 2017, 89, 22
DOI: 10.1021/acs.analchem.6b04631

N-doped carbon dots for highly sensitive and selective sensing of copper ion and sulfide anion in lake water
Jia Ge, Yanmei Shen, Weixia Wang, Yuqing Li and Yu Yang
Journal of Environmental Chemical Engineering, 2021, 9, 105081
DOI: 10.1016/j.jece.2021.105081

Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness?
Christopher J. Chang
Acc. Chem. Res., 2017, 50, 535
DOI: 10.1021/acs.accounts.6b00531

Selective Cu2+ Ion Sensing by Nanoaggregates of Pyridyl‐2,6‐bis(3‐allylsalicylaldehyde)hydrazone
Abhishek Rai, Kamini Tripathi, Avinash Kumar Sonkar, Tony D. James, Saurabh Yashaswee, Surendra Kumar Trigun and Lallan Mishra
ChemistrySelect, 2018, 3, 5395
DOI: 10.1002/slct.201800430

Investigation of photoluminescence properties of a DPA functionalized tris-cyclometalated iridium complex and its potential for metal sensing
Anuson Sansee, Sureemas Meksawangwong, Kittipong Chainok, Wikorn Punyain, Ga-Lai Law, Miroslav Gál and Filip Kielar
Journal of Luminescence, 2024, 269, 120436
DOI: 10.1016/j.jlumin.2023.120436

Multi-stimuli responsive fluorescence of amphiphilic AIEgen copolymers for ultrafast, highly sensitive and selective copper ion detection in water
Pham Quoc Nhien, Po-Hsun Wu, Chia-Hua Wu, Judy I. Wu, Bui Thi Buu Hue, Bo-Wei Du, Fu-Hsiang Ko, Chang-Ching Weng, Yaw-Kuen Li and Hong-Cheu Lin
Sensors and Actuators B: Chemical, 2021, 344, 130241
DOI: 10.1016/j.snb.2021.130241

AIE-based luminescence probes for metal ion detection
Parvej Alam, Nelson L.C. Leung, Jing Zhang, Ryan T.K. Kwok, Jacky W.Y. Lam and Ben Zhong Tang
Coordination Chemistry Reviews, 2021, 429, 213693
DOI: 10.1016/j.ccr.2020.213693

Versatile Coffee Carbon Dots as Lead (ii) and Copper (ii) ion Fluorescence Detectors and Copper Corrosion Inhibitor
Kalema Christopher, Zainal Alim Mas'ud and Novriyandi Hanif
IJSRSET, 2019, 129
DOI: 10.32628/IJSRSET1196371

Construction of an ion-imprinted ratiometric fluorescence sensor integrating zirconium-based metal-organic framework and carbon dots for sensitive detection of copper ion
Lutong Bu, Linchun Nie, Jiawei Liao, Dejing Meng, Wenjing Liu, Rui Yang, Yongli Liu, Na Liu and Qingxiang Zhou
Journal of Environmental Sciences, 2026, 165, 161
DOI: 10.1016/j.jes.2025.08.044

Autofluorescent Hyperbranched Poly(amide amine) as Effective Fluorescent Probe for Label-free Detection of Copper(II) Ions
Ying Zheng, Xiao Wang and Lan Xu
ANAL. SCI., 2017, 33, 1345
DOI: 10.2116/analsci.33.1345

Investigations of cellular copper metabolism in ovarian cancer cells using a ratiometric fluorescent copper dye
Sumayah Mohammed Asiri, Aviva Levina, Elizabeth J. New and Peter A. Lay
J Biol Inorg Chem, 2022, 28, 43
DOI: 10.1007/s00775-022-01978-9

Copper-based nanoplatforms and their role in cancer therapy
Jose I. Garcia-Peiro, Javier Bonet-Aleta and Jose L. Hueso
Coordination Chemistry Reviews, 2025, 534, 216542
DOI: 10.1016/j.ccr.2025.216542

Cope with copper: From copper linked mechanisms to copper-based clinical cancer therapies
Xidi Wang, Miao Zhou, Yu Liu and Zizhen Si
Cancer Letters, 2023, 561, 216157
DOI: 10.1016/j.canlet.2023.216157

Strategic Design of Luminescent Rhenium(I), Ruthenium(II), and Iridium(III) Complexes as Activity‐Based Probes for Bioimaging and Biosensing
Lawrence Cho‐Cheung Lee and Kenneth Kam‐Wing Lo
Chemistry — An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200840

Mitochondria-targeted near-infrared fluorescent probe for monitoring of a Copper(I) in living cells and In vivo
Xiaoli Qian, Wenchao Zhu, Hui Yu, Yue Xu, Wangwang Liu, Hai-Yan Wang and Yi Liu
Dyes and Pigments, 2021, 194, 109561
DOI: 10.1016/j.dyepig.2021.109561

Synthetic fluorescent probes to map metallostasis and intracellular fate of zinc and copper
Giuseppe Trusso Sfrazzetto, Cristina Satriano, Gaetano A. Tomaselli and Enrico Rizzarelli
Coordination Chemistry Reviews, 2016, 311, 125
DOI: 10.1016/j.ccr.2015.11.012

Live‐Cell Copper‐Induced Fluorescence Quenching of the Flavin‐Binding Fluorescent Protein CreiLOV
Wenping Zou, Khoa Le and Melissa L. Zastrow
ChemBioChem, 2020, 21, 1356
DOI: 10.1002/cbic.201900669

Dual-emission ratio fluorescent probes based on carbon dots and gold nanoclusters for visual and fluorescent detection of copper ions
Bo Peng, Mimi Fan, Jiamei Xu, Yang Guo, Yongjun Ma, Min Zhou, Jialei Bai, Jingfeng Wang and Yanjun Fang
Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-04641-9

A wavelength-induced frequency filtering method for fluorescent nanosensors in vivo
Volodymyr B. Koman, Naveed A. Bakh, Xiaojia Jin, Freddy T. Nguyen, Manki Son, Daichi Kozawa, Michael A. Lee, Gili Bisker, Juyao Dong and Michael S. Strano
Nat. Nanotechnol., 2022, 17, 643
DOI: 10.1038/s41565-022-01136-x

Copper Homeostasis, Emerging Central Players in Cancer Immunotherapy
Chengxin Chen, Mengle Peng, Shuhong Liang, Chunwei Li, Lili Zhu, Yaqi Yang, Lifeng Li and Wenhua Xue
J Cellular Molecular Medi, 2025, 29
DOI: 10.1111/jcmm.70611

Detection of Copper(II) in Water by Methylene Blue Derivatives
Carlo Ciarrocchi, Adriana Tumino, Donatella Sacchi, Alessio Orbelli Biroli and Maurizio Licchelli
ChemPhysChem, 2020, 21, 2432
DOI: 10.1002/cphc.202000676

A highly sensitive and selective colorimetric/fluorescent probe for the detection of Ag+ based on a croconium dye
Hong Wang, Yuehan Wu, Yuzhe Zhang, Man Zhou, Song Xu and Zhongyu Li
Optik, 2021, 242, 167325
DOI: 10.1016/j.ijleo.2021.167325

Carbon dots/Ag nanoclusters-based fluorescent probe for ratiometric and visual detection of Cu2+
Lingling Yan, Jiaming Li, Hongxin Cai, Yixin Shao, Guoxiang Zhang, Liang Chen, Yongqiang Wang, Haitao Zong and Yuehong Yin
Journal of Alloys and Compounds, 2023, 945, 169227
DOI: 10.1016/j.jallcom.2023.169227

Ratiometric Luminescence Detection of Copper(I) by a Resonant System Comprising Two Antenna/Lanthanide Pairs
Céline Cepeda, Sergey A. Denisov, Didier Boturyn, Nathan D. McClenaghan and Olivier Sénèque
Inorg. Chem., 2021, 60, 17426
DOI: 10.1021/acs.inorgchem.1c02985

Resonance Rayleigh Scattering Method for Highly Sensitive Detection of Copper Ions in Water Based on Salicylaldeoxime-Copper (Ii) - 2-Methylimidazole Supramolecular
Tingnan Xiao, Yating Wang, Yongshen Hao, Zidong Cai, Meiying Song, Jincan He, Zhengquan Su and Yan Bai
SSRN Journal, 2022
DOI: 10.2139/ssrn.4089167

Naphthalimide-phenanthroimidazole incorporated new fluorescent sensor for “turn-on” Cu2+ detection in living cancer cells
Sellamuthu Anbu, Anup Paul, Kalpana Surendranath, Ahmed Sidali and Armando J.L. Pombeiro
Journal of Inorganic Biochemistry, 2021, 220, 111466
DOI: 10.1016/j.jinorgbio.2021.111466

Colorimetric probing and fluorescent chemosensor features of functionalized sulphonamide-azomethine derivatives
Elif Akhuseyin Yildiz, Diğdem Erdener, Sezen Tekin, Ahmet Karatay, Bahadir Boyacioglu, Hüseyin Ünver, Mustafa Yıldız and Ayhan Elmalı
Journal of Photochemistry and Photobiology A: Chemistry, 2022, 433, 114188
DOI: 10.1016/j.jphotochem.2022.114188

A new endoplasmic reticulum-targeted two-photon fluorescent probe for imaging of superoxide anion in diabetic mice
Haibin Xiao, Xiao Liu, Chuanchen Wu, Yaohuan Wu, Ping Li, Xiaomeng Guo and Bo Tang
Biosensors and Bioelectronics, 2017, 91, 449
DOI: 10.1016/j.bios.2016.12.068

Visual assay for determination of copper ions based on anti-etching of gold nanorods induced by cuprous ions
Song Xu, Xiaojuan Chen, Xin Chen and Yong Liang
Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-4149-3

Nanomedicine Targeting Cuproplasia in Cancer: Labile Copper Sequestration Using Polydopamine Particles Blocks Tumor Growth In Vivo through Altering Metabolism and Redox Homeostasis
Javier Bonet-Aleta, Miguel Encinas-Gimenez, Miku Oi, Aidan T. Pezacki, Victor Sebastian, Alba de Martino, Ana Martín-Pardillos, Pilar Martin-Duque, Jose L. Hueso, Christopher J. Chang and Jesus Santamaria
ACS Appl. Mater. Interfaces, 2024, 16, 29844
DOI: 10.1021/acsami.4c04336

Prolific Selective Recognition of Bio-Apt Ions by Inimitable Er(III) Coordination Polymer: Experimental and In-Silico Insights
Soumyabrata Goswami, Somrita Nag, Debsankar Sahoo, Prodipta Pal, Pradip Kumar Mondal, Sumi Ganguly and Priyabrata Banerjee
Crystal Growth & Design, 2025, 25, 9015
DOI: 10.1021/acs.cgd.5c00824

Copper regulates cyclic-AMP-dependent lipolysis
Lakshmi Krishnamoorthy, Joseph A Cotruvo, Jefferson Chan, Harini Kaluarachchi, Abigael Muchenditsi, Venkata S Pendyala, Shang Jia, Allegra T Aron, Cheri M Ackerman, Mark N Vander Wal, Timothy Guan, Lukas P Smaga, Samouil L Farhi, Elizabeth J New, Svetlana Lutsenko and Christopher J Chang
Nat Chem Biol, 2016, 12, 586
DOI: 10.1038/nchembio.2098

Rapid Detection of Copper in Biological Systems Using Click Chemistry
Wenshu Zheng, Huiling Li, Wenwen Chen, Jiangjiang Zhang, Nuoxin Wang, Xuefeng Guo and Xingyu Jiang
Small, 2018, 14
DOI: 10.1002/smll.201703857

Mitochondria-targeting two-photon fluorescent probe for sequential recognition of Cu2+ and ATP in neurons and zebrafish
Xuefeng Wang, Xinlei Song, Juanjuan Wu, Pingxuan Dong, Xiaoxia Men, Xiaolei Zhang, Fan Yang and Wan Sun
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 303, 123260
DOI: 10.1016/j.saa.2023.123260

A pyrene-based multifunctional fluorescent probe for the detection of Cu2+ and Al3+
Chunwei Yu, Mei Yang and Jun Zhang
Microchemical Journal, 2025, 208, 112531
DOI: 10.1016/j.microc.2024.112531

A cancer cell-specific fluorescent probe for imaging Cu 2+ in living cancer cells
Chao Wang, Baoli Dong, Xiuqi Kong, Xuezhen Song, Nan Zhang and Weiying Lin
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 182, 32
DOI: 10.1016/j.saa.2017.03.058

Study on TICT emission of TPE-BODIPY derivatives mediated by methyl group on BODIPY
Yun Zhao, Sile He, Jinyue Yang, Hao Sun, Xiaofeng Shen, Xiangen Han and Zhonghai Ni
Optical Materials, 2018, 81, 102
DOI: 10.1016/j.optmat.2018.05.023

How Mammalian Cells Acquire Copper: An Essential but Potentially Toxic Metal
Jack H. Kaplan and Edward B. Maryon
Biophysical Journal, 2016, 110, 7
DOI: 10.1016/j.bpj.2015.11.025

Small Upconverting Fluorescent Nanoparticles for Biosensing and Bioimaging
Guang‐Rong Tan, Menghan Wang, Chin‐Ying Hsu, Nanguang Chen and Yong Zhang
Advanced Optical Materials, 2016, 4, 984
DOI: 10.1002/adom.201600141

A coumarin-based fluorescent probe for sequential detection of Cu2+ and GSH with its application in visual sensing
Yingying Zhao, Qiurui Ma, Yingli Jiang, Xuexin Liang, Songyu Wang, Shangyi Zhao, Wenlin Li and Xinli Yang
Microchemical Journal, 2025, 215, 114552
DOI: 10.1016/j.microc.2025.114552

Theoretical exploration for recognition mechanism of two similar coumarin-based probes on Hg2+ and Cu2+
Haiyan Wang, Shun Yao, Qian Liu, Kun Wang, Haizhu Yu, Xiaojiao Zhu, Lin Kong and Hongping Zhou
Journal of Molecular Structure, 2019, 1198, 126870
DOI: 10.1016/j.molstruc.2019.126870

Fluorescent probe visualization for selective detection of cuprous ion
Ranhao Yin, Long Yu, Pengchen Su, Guoqiang Liu, Hongwei Ge and Suhua Wang
ANAL. SCI., 2022, 38, 145
DOI: 10.2116/analsci.21P218

Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research
Jonathan P. Mochel, Albert E. Jergens, Dawn Kingsbury, Hyun Jung Kim, Martín G. Martín and Karin Allenspach
AAPS J, 2018, 20
DOI: 10.1208/s12248-017-0178-1

Design of Metal–Organic Frameworks with Strong and Weak Field Ligands for Fluorescence–Based Segregation of Metal Ion Redox States
Susanta Dinda, Pintu Das, Bidyadhar Mahato and Debajyoti Ghoshal
Inorg. Chem., 2025, 64, 24110
DOI: 10.1021/acs.inorgchem.5c04420

DNAzyme-Based Lithium-Selective Imaging Reveals Higher Lithium Accumulation in Bipolar Disorder Patient-Derived Neurons
Claire E. McGhee, Zhenglin Yang, Weijie Guo, Yuting Wu, Mingkuan Lyu, Cynthia J. DeLong, Shanni Hong, Yuan Ma, Melvin G. McInnis, K. Sue O’Shea and Yi Lu
ACS Cent. Sci., 2021, 7, 1809
DOI: 10.1021/acscentsci.1c00843

In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease
Marie C. Heffern, Hyo Min Park, Ho Yu Au-Yeung, Genevieve C. Van de Bittner, Cheri M. Ackerman, Andreas Stahl and Christopher J. Chang
Proc. Natl. Acad. Sci. U.S.A., 2016, 113, 14219
DOI: 10.1073/pnas.1613628113

A review on dual detection of Cu2+ and Ni2+ ions by using single fluorometric and colorimetric organic molecular probes
Mini Loya, Suprava Ghosh and Ananta Kumar Atta
Journal of Molecular Structure, 2023, 1278, 134949
DOI: 10.1016/j.molstruc.2023.134949

Dual-locked probes: In vivo monitoring of neural mitochondrial Cu biology
Jinping Liu, Yunjia Xu, Jiqing Bian, Jiaxuan Cai, Yifang Song, Jingru Yu, Juandi Wei, Xu Wang, Qi Ai, Xi Li and Baoxiang Gao
Sensors and Actuators B: Chemical, 2025, 445, 138551
DOI: 10.1016/j.snb.2025.138551

Air‐Stable Spirofluorene‐Containing Ladder‐Type Bis(alkynyl)borane Compounds with Readily Tunable Full Color Emission Properties
Ben Yiu‐Wing Wong, Hok‐Lai Wong, Yi‐Chun Wong, Mei‐Yee Chan and Vivian Wing‐Wah Yam
Chemistry A European J, 2016, 22, 15095
DOI: 10.1002/chem.201602829

Construction of a New Probe Based on Copper Chaperone Protein for Detecting Cu2+ in Cells
Jing Ren, Lin Li, Hongfei Han, Yi Chen, Ziying Qin and Zhen Song
Molecules, 2024, 29, 1020
DOI: 10.3390/molecules29051020

AIE-active Cyclen-BODIPYs as multiresponsive fluorescent probes for imaging in biological samples: Design and comprehensive study
Denis Y. Uvarov, Nina A. Sapoletova, Sergey E. Kushnir, Sofiya L. Selektor, Ivan S. Golovanov, Anatoly Y. Chursin, Alexander M. Scherbakov, Diana I. Salnikova, Pavel B. Kopnin, Natalya G. Kolotyrkina, Artem Fakhrutdinov, Victoria Malakhova, Guzel Sibgatullina, Dmitry Samigullin, Igor V. Zavarzin, Christine Goze, Franck Denat and Yulia A. Volkova
Talanta, 2025, 295, 128283
DOI: 10.1016/j.talanta.2025.128283

Naked-eye chemosensor with high absolute fluorescence quantum yield for selective detection of Cu(II) and cell imaging
Hai Xie, Qingqing Hu, Xiuting Qin, Yali Zhang, Lu Li and Ji Li
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 283, 121740
DOI: 10.1016/j.saa.2022.121740

A Coumarin-Based Fluorescent Probe for Selective Detection of Cu(II) and Imaging in Human Cell
Shan Gao, Ai-Ling Wang and Ming-Zhe Wang
Russ J Org Chem, 2024, 60, 467
DOI: 10.1134/S107042802403014X

Two multifunctional luminescent cobalt metal-organic frameworks for selectively and sensitively sensing of Cu2+, MnO4- and picric acid in water
Ruimin Yuan, Kun Huang, Yi Zou, Xiangyu Zhang and Dabin Qin
Journal of Solid State Chemistry, 2022, 307, 122875
DOI: 10.1016/j.jssc.2021.122875

A novel BF2–curcumin-based fluorescent chemosensor for detection of Cu2+ in aqueous solution and living cells
Yuan Li, Yu-Xin Ji, Lin-Jiang Song, Yi Zhang, Zi-Cheng Li, Li Yang and Wen-Cai Huang
Res Chem Intermed, 2018, 44, 5169
DOI: 10.1007/s11164-018-3416-y

Cu(I)-Catalyzed Click Reaction-Triggered 3D DNA Walker for Constructing an “OFF–ON” Fluorescent Biosensor for Cu2+ Detection
Zhen Wang, Nan Jia, Xumei Zhou, Jing Han and Huaiyu Bu
ACS Appl. Bio Mater., 2021, 4, 3571
DOI: 10.1021/acsabm.1c00073

The ionophore thiomaltol induces rapid lysosomal accumulation of copper and apoptosis in melanoma
Ottis Scrivner, Long Dao, M Karen Newell-Rogers, Babbak Shahandeh, Frank L Meyskens, Susan Kurumi Kozawa, Feng Liu-Smith, Germán Plascencia-Villa, Miguel José-Yacamán, Shang Jia, Christopher J Chang and Patrick J Farmer
Metallomics, 2022, 14
DOI: 10.1093/mtomcs/mfab074

Carnosine modulates the Sp1-Slc31a1/Ctr1 copper-sensing system and influences copper homeostasis in murine CNS-derived cells
Amilcare Barca, Stefania Ippati, Emanuela Urso, Carla Vetrugno, Carlo Storelli, Michele Maffia, Alessandro Romano and Tiziano Verri
American Journal of Physiology-Cell Physiology, 2019, 316, C235
DOI: 10.1152/ajpcell.00106.2018

Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI
M. Thomas Morgan, Bo Yang, Shefali Harankhedkar, Arielle Nabatilan, Daisy Bourassa, Adam M. McCallum, Fangxu Sun, Ronghu Wu, Craig R. Forest and Christoph J. Fahrni
Angew Chem Int Ed, 2018, 57, 9711
DOI: 10.1002/anie.201804072

An Endeavor in the Reaction-Based Approach to Fluorescent Probes for Biorelevant Analytes: Challenges and Achievements
Subhankar Singha, Yong Woong Jun, Sourav Sarkar and Kyo Han Ahn
Acc. Chem. Res., 2019, 52, 2571
DOI: 10.1021/acs.accounts.9b00314

Cu in biology: Unleashed by O2 and now irreplaceable
Linda H. Doerrer
Inorganica Chimica Acta, 2018, 481, 4
DOI: 10.1016/j.ica.2017.11.051

Glutathione limits aquacopper(I) to sub-femtomolar concentrations through cooperative assembly of a tetranuclear cluster
M. Thomas Morgan, Lily Anh H. Nguyen, Haylie L. Hancock and Christoph J. Fahrni
Journal of Biological Chemistry, 2017, 292, 21558
DOI: 10.1074/jbc.M117.817452

A Luminescent NOTA-Based Terbium(III) “Turn-Off” Sensor for Copper
Michèle Clerc, Franz Heinemann, Bernhard Spingler and Gilles Gasser
Inorg. Chem., 2020, 59, 669
DOI: 10.1021/acs.inorgchem.9b02934

Harnessing the Dual Properties of Thiol‐Grafted Cellulose Paper for Click Reactions: A Powerful Reducing Agent and Adsorbent for Cu
Jordi Rull‐Barrull, Martin d'Halluin, Erwan Le Grognec and François‐Xavier Felpin
Angew Chem Int Ed, 2016, 55, 13549
DOI: 10.1002/anie.201606760

A hydrophilic naphthalimide-based fluorescence chemosensor forCu2+ ion: Sensing properties, cell imaging and molecular logic behavior
Shucai Liang, Qiao Tong, Xiaoning Qin, Xiaoyan Liao, Qian Li and Guoping Yan
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 230, 118029
DOI: 10.1016/j.saa.2020.118029

A lysosome-targeted near-infrared fluorescent probe for cell imaging of Cu2+
Yin Chen, Zhiqing Long, Chengcheng Wang, Jingjing Zhu, Shasha Wang, Yan Liu, Peng Wei and Tao Yi
Dyes and Pigments, 2022, 204, 110472
DOI: 10.1016/j.dyepig.2022.110472

A dual-functional chemosensor for fluorescent on-off and ratiometric detection of Cu2+ and Hg2+ and its application in cell imaging
Shuang Zeng, Shi-Jie Li, Xue-Jiao Sun, Ting-Ting Liu and Zhi-Yong Xing
Dyes and Pigments, 2019, 170, 107642
DOI: 10.1016/j.dyepig.2019.107642

Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems
Allegra T. Aron, Karla M. Ramos-Torres, Joseph A. Cotruvo and Christopher J. Chang
Acc. Chem. Res., 2015, 48, 2434
DOI: 10.1021/acs.accounts.5b00221

Tuning the Sensing Properties of N and S Co-Doped Carbon Dots for Colorimetric Detection of Copper and Cobalt in Water
Ramanand Bisauriya, Simonetta Antonaroli, Matteo Ardini, Francesco Angelucci, Antonella Ricci and Roberto Pizzoferrato
Sensors, 2022, 22, 2487
DOI: 10.3390/s22072487

Rational design of peptide-based fluorescent probe for sequential recognitions of Cu(II) ions and glyphosate: Smartphone, test strip, real sample and living cells applications
Chunmei Pu, Shiyang Li, Xinlin Cao, Miao Zhou, Weiliang Deng and Peng Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 317, 124424
DOI: 10.1016/j.saa.2024.124424

Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson’s disease and liver metastasis
Melissa Y. Lucero, Yuqi Tang, Chloe J. Zhang, Shengzhang Su, Joseph A. Forzano, Valeria Garcia, Xin Huang, David Moreno and Jefferson Chan
Proc. Natl. Acad. Sci. U.S.A., 2021, 118
DOI: 10.1073/pnas.2106943118

Resonance Rayleigh scattering method for highly sensitive detection of copper ions in water based on salicylaldeoxime-copper (Ⅱ)- 2-methylimidazole supramolecular
Tingnan Xiao, Yating Wang, Yongshen Hao, Zidong Cai, Meiying Song, Jincan He, Zhengquan Su and Yan Bai
Microchemical Journal, 2022, 181, 107744
DOI: 10.1016/j.microc.2022.107744

Sterically hindered phenolic azomethine dyes derived from aliphatic amines: solvatochromism, DFT studies and antioxidant activity
Iveta S. Turomsha, Maxim Y. Gvozdev and Natalia V. Loginova
ANAL. SCI., 2025, 41, 1763
DOI: 10.1007/s44211-025-00837-2

Imidazo[1,2-a]pyridine-substituted coumarin as a selective ratiometric sensor for Cu2+ ion
Shaily, Ajay Kumar and Naseem Ahmed
Supramolecular Chemistry, 2017, 29, 146
DOI: 10.1080/10610278.2016.1190453

In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection
Allegra T. Aron, Marie C. Heffern, Zachery R. Lonergan, Mark N. Vander Wal, Brian R. Blank, Benjamin Spangler, Yaofang Zhang, Hyo Min Park, Andreas Stahl, Adam R. Renslo, Eric P. Skaar and Christopher J. Chang
Proc. Natl. Acad. Sci. U.S.A., 2017, 114, 12669
DOI: 10.1073/pnas.1708747114

Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu2+ in the Brain
Jianping Zhu, Marcus E. Graziotto, Veronica Cottam, Tom Hawtrey, Liam D. Adair, Benjamin G. Trist, Nguyen T.H. Pham, Jourdin R. C. Rouaen, Carolyn Ohno, Marcus Heisler, Orazio Vittorio, Kay L. Double and Elizabeth J. New
ACS Sens., 2024, 9, 2858
DOI: 10.1021/acssensors.3c02549

Triphenylamine‐Based Dual Chemosensor for Cu2+ and Co2+ Ions and Volatile Acid Vapour Sensor, DFT Calculations
Aravind R. Nesaragi, Jyoti Nagalik, Mounesh, Sharanakumar T. M., Halligudra Guddappa, Tahani Mazyad Almutairi, Sanjeev R. Inamdar and Anup Pandith
Applied Organom Chemis, 2025, 39
DOI: 10.1002/aoc.70105

Induction of Cuproptosis by Dichloromethane Extract From Patrinia scabiosaefolia Fisch on K562 Cells
Yuan Lu, Leyuan Mi, Peipei Zhang, Yang Chen, Xinyi Bai, Kejing Li, Ying Zhang and Juan Li
Environmental Toxicology, 2025, 40, 1193
DOI: 10.1002/tox.24516

Selective Metal‐Ion Detection and Activatable Photosensitization Properties of a Tetraphenylethylene‐Based Salicylideneimine
Parvati Marandi, P. P. Praveen Kumar, Paloth Venugopalan and Prakash P. Neelakandan
ChemistrySelect, 2019, 4, 5707
DOI: 10.1002/slct.201901035

Component reconstitution-driven photoelectrochemical sensor for sensitive detection of Cu2+ based on advanced CuS/CdS p-n junction
Jing Liu, Ying Liu, Wei Wang, Jing Li, Xinyuan Yu, Qinshu Zhu and Zhihui Dai
Sci. China Chem., 2019, 62, 1725
DOI: 10.1007/s11426-019-9579-2

Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI
M. Thomas Morgan, Bo Yang, Shefali Harankhedkar, Arielle Nabatilan, Daisy Bourassa, Adam M. McCallum, Fangxu Sun, Ronghu Wu, Craig R. Forest and Christoph J. Fahrni
Angewandte Chemie, 2018, 130, 9859
DOI: 10.1002/ange.201804072

Efficient and selective Cu2+ detection for enhanced photoelectrochemical senor based on soluble melem unit couples with carbon nitride
Dong Liang, Rui Shan, Peng Chen, Hongyuan Chen, Shuxiao Wang, Jing Gu, Haoran Yuan and Yong Chen
Microchemical Journal, 2024, 196, 109632
DOI: 10.1016/j.microc.2023.109632

Recent Endeavors on Molecular Imaging for Mapping Metals in Biology
Jing Gao, Yuncong Chen, Zijian Guo and Weijiang He
Biophys Rep, 2020, 6, 159
DOI: 10.1007/s41048-020-00118-7

Fluorescent chemosensors for copper(II) ion: Structure, mechanism and application
Shuo Liu, Yan-Mei Wang and Jie Han
Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 2017, 32, 78
DOI: 10.1016/j.jphotochemrev.2017.06.002

Unimolecular Chemo-fluoro-luminescent Reporter for Crosstalk-Free Duplex Imaging of Hepatotoxicity
Penghui Cheng, Qingqing Miao, Jingchao Li, Jiaguo Huang, Chen Xie and Kanyi Pu
J. Am. Chem. Soc., 2019, 141, 10581
DOI: 10.1021/jacs.9b02580

Copper ion luminescence on/off sensing by a quinoline-appended ruthenium(II)-polypyridyl complex in aqueous media
Pramod Kumar and Sushil Kumar
Journal of Molecular Structure, 2020, 1202, 127242
DOI: 10.1016/j.molstruc.2019.127242

A Novel Biscarbazole-Xanthene Hybrid Fluorescent Probe for Selective and Sensitive Detection of Cu2+ and Applications in Bioimaging
Kun Huang, Defang Han, Xianglin Li, Mengni Peng, Qi Qiu and Dabin Qin
J Fluoresc, 2019, 29, 727
DOI: 10.1007/s10895-019-02393-1

Wahrnehmung der chemischen Prozesse in einzelnen Organellen mit niedermolekularen Fluoreszenzsonden
Wang Xu, Zebing Zeng, Jian‐Hui Jiang, Young‐Tae Chang and Lin Yuan
Angewandte Chemie, 2016, 128, 13858
DOI: 10.1002/ange.201510721

Design, synthesis and applications of a dual-mode peptidyl probe for sequential determination of Cu2+ and S2− in food and biological systems
Mengying Jia, Yi Ren, Shiyi Xiong, Ying Su, Meixiao Zhu and Peng Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 357, 127799
DOI: 10.1016/j.saa.2026.127799

Mesoporous Fe2O3–CdS Heterostructures for Real-Time Photoelectrochemical Dynamic Probing of Cu2+
Jing Tang, Jun Li, Yueyu Zhang, Biao Kong, Yiliguma, Yang Wang, Yingzhou Quan, Hao Cheng, Abdullah M. Al-Enizi, Xingao Gong and Gengfeng Zheng
Anal. Chem., 2015, 87, 6703
DOI: 10.1021/acs.analchem.5b00844

A novel quinoline-based fluorescent sensor for imaging Copper (II) in living cells
Chen Zhou, Heng Liu and Yinan Zhang
Main Group Chemistry, 2018, 17, 53
DOI: 10.3233/MGC-180248

Tryptophan-based fluorescent sensor for selective Cu2+ detection in aqueous media and its docking study for anticancer effects
Ghodsi Mohammadi Ziarani, Shikofa Khorrami, Fatemeh Mohajer, Sunil V. Gaikwad, Najibullah Hassani, Alireza Badiei, Siavash Iravani and Rajender S. Varma
Results in Chemistry, 2024, 7, 101362
DOI: 10.1016/j.rechem.2024.101362

Recent Advances in Nanopore Technology for Copper Detection and Their Potential Applications
Alexander N. Vaneev, Roman V. Timoshenko, Petr V. Gorelkin, Natalia L. Klyachko and Alexander S. Erofeev
Nanomaterials, 2023, 13, 1573
DOI: 10.3390/nano13091573

An easily accessible optical chemosensor for Cu2+ based on novel imidazoazine framework, its performance characteristics and potential applications
Lokesh Kumar Kumawat, Manoj Kumar, Priyanka Bhatt, Anuj Sharma, M. Asif and Vinod Kumar Gupta
Sensors and Actuators B: Chemical, 2017, 240, 365
DOI: 10.1016/j.snb.2016.08.184

Stepwise Assembly of Turn‐on Fluorescence Sensors in Multicomponent Metal–Organic Frameworks for in Vitro Cyanide Detection
Jialuo Li, Shuai Yuan, Jun‐Sheng Qin, Jiandong Pang, Peng Zhang, Yingmu Zhang, Yanyan Huang, Hannah F. Drake, Wenshe R. Liu and Hong‐Cai Zhou
Angew Chem Int Ed, 2020, 59, 9319
DOI: 10.1002/anie.202000702

Research on endoplasmic reticulum–targeting fluorescent probes and endoplasmic reticulum stress–mediated nanoanticancer strategies: A review
Li Qiao, Xinxin Shao, Shijie Gao, Zheng Ming, Xianjun Fu and Qingcong Wei
Colloids and Surfaces B: Biointerfaces, 2021, 208, 112046
DOI: 10.1016/j.colsurfb.2021.112046

Copper Capture in a Thioether-Functionalized Porous Polymer Applied to the Detection of Wilson’s Disease
Sumin Lee, Gokhan Barin, Cheri M. Ackerman, Abigael Muchenditsi, Jun Xu, Jeffrey A. Reimer, Svetlana Lutsenko, Jeffrey R. Long and Christopher J. Chang
J. Am. Chem. Soc., 2016, 138, 7603
DOI: 10.1021/jacs.6b02515

Metal ion responsive bifunctional bis(indolyl)methane derivative: Excitation-triggered alteration in the sensing behavior
Rikitha S. Fernandes and Nilanjan Dey
Materials Chemistry and Physics, 2023, 302, 127637
DOI: 10.1016/j.matchemphys.2023.127637

Synthesis of biscarbazole derivative, detection of the “on-off” sensor property of Cu2+ by fluorimetry, and anti-cancer evaluation
Sümeyye Çol, Sinan Başçeken and Arif Baran
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 320, 124624
DOI: 10.1016/j.saa.2024.124624

A new copper(II) selective fluorescence probe based on naphthalimide: Synthesis, mechanism and application in living cells
Guangjie He, Qingtao Meng, Xiuwen Zhao, Cheng He, Peng Zhou and Chunying Duan
Inorganic Chemistry Communications, 2016, 65, 28
DOI: 10.1016/j.inoche.2015.10.022

Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium
Katerina Akassoglou, Dritan Agalliu, Christopher J. Chang, Dimitrios Davalos, Jaime Grutzendler, Elizabeth M. C. Hillman, Baljit S. Khakh, David Kleinfeld, Dorian B. McGavern, Sarah J. Nelson and Berislav V. Zlokovic
Front. Neurosci., 2016, 10
DOI: 10.3389/fnins.2016.00046

Addressing Multiple Ions Using Single Optical Probe: Multi‐Color Response via Mutually Independent Sensing Pathways
Nilanjan Dey, Subham Bhattacharjee and Santanu Bhattacharya
ChemistrySelect, 2020, 5, 452
DOI: 10.1002/slct.201902920

Copper (II) synergistic AS1411 conjunction with chemical decaging reactions for selective fluorescence imaging and prodrug activation in living systems
Kun Chen, Guangrong Zou, Wei Xiong, Zhiyong He, Shen Yan, Shanshan Qin, Qi Wang, Hengjiang Cong, Chun-Jiang Wang and Xiang Zhou
Sensors and Actuators B: Chemical, 2021, 349, 130773
DOI: 10.1016/j.snb.2021.130773

A new diarylethene based chemosensor for colorimetric recognition of arginine and fluorescent detection of Cu2+
Yanmei Jia, Mengmeng Lu, Shiqiang Cui and Shouzhi Pu
Journal of Photochemistry and Photobiology A: Chemistry, 2022, 423, 113592
DOI: 10.1016/j.jphotochem.2021.113592

Relay detection of Cu2+ and bovine serum albumin by a dansyl derivative-based fluorescent probe
Honghui Cai, Yuehui Liang, Lilian Huang and Jing Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 277, 121281
DOI: 10.1016/j.saa.2022.121281

A HaloTag-Based Multicolor Fluorogenic Sensor Visualizes and Quantifies Proteome Stress in Live Cells Using Solvatochromic and Molecular Rotor-Based Fluorophores
Yu Liu, Kun Miao, Yinghao Li, Matthew Fares, Shuyuan Chen and Xin Zhang
Biochemistry, 2018, 57, 4663
DOI: 10.1021/acs.biochem.8b00135

Harnessing the Dual Properties of Thiol‐Grafted Cellulose Paper for Click Reactions: A Powerful Reducing Agent and Adsorbent for Cu
Jordi Rull‐Barrull, Martin d'Halluin, Erwan Le Grognec and François‐Xavier Felpin
Angewandte Chemie, 2016, 128, 13747
DOI: 10.1002/ange.201606760

Lanthanide‐Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Lei Zhang, André F. Martins, Piyu Zhao, Yunkou Wu, Gyula Tircsó and A. Dean Sherry
Angew Chem Int Ed, 2017, 56, 16626
DOI: 10.1002/anie.201707959

Activity‐Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond
Kevin J. Bruemmer, Steven W. M. Crossley and Christopher J. Chang
Angew Chem Int Ed, 2020, 59, 13734
DOI: 10.1002/anie.201909690

A New pH-Dependent Macrocyclic Rhodamine B-Based Fluorescent Probe for Copper Detection in White Wine
Nour Doumani, Elias Bou-Maroun, Jacqueline Maalouly, Maya Tueni, Adrien Dubois, Claire Bernhard, Franck Denat, Philippe Cayot and Nicolas Sok
Sensors, 2019, 19, 4514
DOI: 10.3390/s19204514

An Efficient D‐π‐A‐π‐D‐Type Fluorescent Probe for Selective and Sensitive Detection of Cu2+ and CN− Ions Through Fluorescence On–Off Responses
Mohammed Kaleem, Rimpi Bhandari, Ravisen Rai and Arvind Misra
Luminescence, 2026, 41
DOI: 10.1002/bio.70402

Nanopore-Based Strategy for Sensing of Copper(II) Ion and Real-Time Monitoring of a Click Reaction
Liping Liu, Zhen Fang, Xiangjiang Zheng and Dongmei Xi
ACS Sens., 2019, 4, 1323
DOI: 10.1021/acssensors.9b00236

Design, properties and application of a facile fluorescence switch for Cu(II)
Haipeng Diao, Weiping Niu, Wen Liu, Liheng Feng and Jun Xie
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 170, 65
DOI: 10.1016/j.saa.2016.07.014

Aggregation of Microtubule Binding Repeats of Tau Protein is Promoted by Cu2+
Soha Ahmadi, Shaolong Zhu, Renu Sharma, Bing Wu, Ronald Soong, R. Dutta Majumdar, Derek J. Wilson, Andre J. Simpson and Heinz-Bernhard Kraatz
ACS Omega, 2019, 4, 5356
DOI: 10.1021/acsomega.8b03595

Subcellular Localization of Copper—Cellular Bioimaging with Focus on Neurological Disorders
Barbara Witt, Dirk Schaumlöffel and Tanja Schwerdtle
IJMS, 2020, 21, 2341
DOI: 10.3390/ijms21072341

Ratiometric fluorescent probe based on pyrrole-modified rhodamine 6G hydrazone for the imaging of Cu2+ in lysosomes
Wei-Na Wu, Hao Wu, Run-Bin Zhong, Yuan Wang, Zhi-Hong Xu, Xiao-Lei Zhao, Zhou-Qing Xu and Yun-Chang Fan
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 212, 121
DOI: 10.1016/j.saa.2018.12.041

The Role of Copper Homeostasis in Brain Disease
Yumei An, Sunao Li, Xinqi Huang, Xueshi Chen, Haiyan Shan and Mingyang Zhang
IJMS, 2022, 23, 13850
DOI: 10.3390/ijms232213850

An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells
Allegra T. Aron, Morten O. Loehr, Jana Bogena and Christopher J. Chang
J. Am. Chem. Soc., 2016, 138, 14338
DOI: 10.1021/jacs.6b08016

A rhodamine derivative probe for highly selective detection of Cu(II)
Liming Hu, Yifan Lin, Peng Wang, Hongsheng Zhang, Minyao Liu and Shanyan Mo
Front. Biosci. (Landmark Ed), 2022, 27
DOI: 10.31083/j.fbl2701028

Stability constants of bio-relevant, redox-active metals with amino acids: The challenges of weakly binding ligands
Jaime M. Murphy, Brian A. Powell and Julia L. Brumaghim
Coordination Chemistry Reviews, 2020, 412, 213253
DOI: 10.1016/j.ccr.2020.213253

Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores
Shang Jia, Karla M. Ramos-Torres, Safacan Kolemen, Cheri M. Ackerman and Christopher J. Chang
ACS Chem. Biol., 2018, 13, 1844
DOI: 10.1021/acschembio.7b00748

Manganese Mapping Using a Fluorescent Mn2+ Sensor and Nanosynchrotron X-ray Fluorescence Reveals the Role of the Golgi Apparatus as a Manganese Storage Site
Sayani Das, Asuncion Carmona, Kaustav Khatua, Francesco Porcaro, Andrea Somogyi, Richard Ortega and Ankona Datta
Inorg. Chem., 2019, 58, 13724
DOI: 10.1021/acs.inorgchem.9b01389

Pyrrole-quinazoline derivative as an easily accessible turn-off optical chemosensor for Cu2+ and resultant Cu2+ complex as a turn-on sensor for pyrophosphate in almost neat aqueous solution
Wan-Wan Wang, Yuan Wang, Wei-Na Wu, Xiao-Lei Zhao, Zhou-Qing Xu, Zhi-Hong Xu, Xiao-Xia Li and Yun-Chang Fan
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 226, 117592
DOI: 10.1016/j.saa.2019.117592

Colorimetric assay of copper ions based on the inhibition of peroxidase-like activity of MoS 2 nanosheets
Huan Chen, Zhihong Li, Xueting Liu, Jianhai Zhong, Tianran Lin, Liangqia Guo and Fengfu Fu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 185, 271
DOI: 10.1016/j.saa.2017.05.071

The copper(II) binding centres of carbonic anhydrase are differently affected by reductants that ensure the redox intracellular environment
Giovanni Tabbì, Antonio Magrì and Enrico Rizzarelli
Journal of Inorganic Biochemistry, 2019, 199, 110759
DOI: 10.1016/j.jinorgbio.2019.110759

Metalloallostery and Transition Metal Signaling: Bioinorganic Copper Chemistry Beyond Active Sites
Vanha N. Pham and Christopher J. Chang
Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202213644

Simultaneous Imaging of Cu+ and Cu2+ in Neural Cells Using DNAzyme Probes Reveals Mechanistic Link Between Copper Redox Imbalance and Amyloid Pathology
Xiangli Shao, Zhenglin Yang, Zhihao Xu, Weijie Guo, Whitney Lewis, Boyi Gan and Yi Lu
Angew Chem Int Ed, 2026, 65
DOI: 10.1002/anie.202524237

Preorganized PSP Ligands Yield Monomeric Cu(I) Complexes with Subzeptomolar Cu(I) Dissociation Constants
Farzaneh Saeedifard, M. Thomas Morgan, John Bacsa and Christoph J. Fahrni
Inorg. Chem., 2019, 58, 13631
DOI: 10.1021/acs.inorgchem.9b00965

Molecular Container and Metal Ion Sensor Chiral Cavitands
Arpita S. Desai, Thennati Rajamannar and Shailesh R. Shah
ChemistrySelect, 2020, 5, 10588
DOI: 10.1002/slct.202002273

Ratiometric Fluorescent Probes for Copper Ion Detection and Cuproptosis Studies
Yongbao Huang, Zhengjia Wang, Fengfeng Feng, Yan Wang, Ruofei Zhu, Xiaolei Zhang, Sai Zhang, Minghai Qu and Fan Yang
CAC, 2025, 21, 610
DOI: 10.2174/0115734110326657240909064134

A TPA-caged precursor of (imino)coumarin for “turn-on” fluorogenic detection of Cu+
Zhangjun Hu, Jiwen Hu, Hui Wang, Qiong Zhang, Meng Zhao, Caroline Brommesson, Yupeng Tian, Hongwen Gao, Xuanjun Zhang and Kajsa Uvdal
Analytica Chimica Acta, 2016, 933, 189
DOI: 10.1016/j.aca.2016.05.031

Metalloallostery and Transition Metal Signaling: Bioinorganic Copper Chemistry Beyond Active Sites
Vanha N. Pham and Christopher J. Chang
Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202213644

High affinity of AS1411 toward copper; its application in a sensitive aptasensor for copper detection
Amirhossein Bahreyni, Mohammad Ramezani, Mona Alibolandi, Pirooz Hassanzadeh, Khalil Abnous and Seyed Mohammad Taghdisi
Analytical Biochemistry, 2019, 575, 1
DOI: 10.1016/j.ab.2019.03.016

From and to the Golgi – defining the Wilson disease protein road map
Roman S. Polishchuk and Elena V. Polishchuk
FEBS Letters, 2019, 593, 2341
DOI: 10.1002/1873-3468.13575

AIE+ESIPT Active Hydroxybenzothiazole for Intracellular Detection of Cu2+: Anticancer and Anticounterfeiting Applications
Rajdeep Kaur, Rasdeep Kour, Satwinder Singh Marok, Satwinderjeet Kaur and Prabhpreet Singh
Molecules, 2022, 27, 7678
DOI: 10.3390/molecules27227678

Discovery of an unusual copper homeostatic mechanism in yeast cells respiring on minimal medium and an unexpectedly diverse labile copper pool
Joshua E. Kim, Seoyoung Jeon and Paul A. Lindahl
Journal of Biological Chemistry, 2023, 299, 105435
DOI: 10.1016/j.jbc.2023.105435

Dual-phase isocoumarin based fluorescent and colorimetric sensors for Cu2+ detection in environmental and biological applications
Annah Gupta, Tavishi Chopra, Sonakshi Sasan, Usha Kumari Verma, Vaishali Sharma, Abhinit Kumar, Raman Parkesh and Kamal K. Kapoor
Microchemical Journal, 2026, 220, 116263
DOI: 10.1016/j.microc.2025.116263

A novel near-infrared fluorescent platform with good photostability and the application for a reaction-based Cu2+ probe in living cells
Keyin Liu, Huiming Shang, Fangfang Meng, Yong Liu and Weiying Lin
Talanta, 2016, 147, 193
DOI: 10.1016/j.talanta.2015.09.052

Copper homeostasis and cuproptosis in Alzheimer's disease (Review)
Chao Cong, He Cong, Yuan Yao, Yuquan Bai and Lianwei Xu
Int J Mol Med, 2025, 56, 1
DOI: 10.3892/ijmm.2025.5613

Coumarin-based near-infrared fluorogenic probes: Recent advances, challenges and future perspectives
Yufan Fan, Yue Wu, Jie Hou, Ping Wang, Xiaojun Peng and Guangbo Ge
Coordination Chemistry Reviews, 2023, 480, 215020
DOI: 10.1016/j.ccr.2023.215020

Novel triazole-based AIE materials: Dual-functional, highly sensitive and selective fluorescence probe
Alim Abdurahman, Lu Wang, Zhaoxia Zhang, Yuting Feng, Yihan Zhao and Ming Zhang
Dyes and Pigments, 2020, 174, 108050
DOI: 10.1016/j.dyepig.2019.108050

A colorimetric chemosensor for quantification of exchangeable Cu2+ in soil
Daniel J. Fanna, Luís M.P. Lima, Gang Wei, Feng Li and Jason K. Reynolds
Chemosphere, 2020, 238, 124664
DOI: 10.1016/j.chemosphere.2019.124664

Near‐Infrared Upconversion Chemodosimeter for In Vivo Detection of Cu2+ in Wilson Disease
Yi Liu, Qianqian Su, Min Chen, Yi Dong, Yibing Shi, Wei Feng, Zhi‐Ying Wu and Fuyou Li
Advanced Materials, 2016, 28, 6625
DOI: 10.1002/adma.201601140

Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation
Xiangwen Liao, Huinan Li, Yu Guo, Fang Yang, Yushou Chen, Xiaojun He, Hongyan Li, Wei Xia, Zong-Wan Mao and Hongzhe Sun
Journal of Biological Chemistry, 2022, 298, 101587
DOI: 10.1016/j.jbc.2022.101587

A novel peptide-based fluorescence chemosensor for selective imaging of hydrogen sulfide both in living cells and zebrafish
Peng Wang, Jiang Wu, Cuixia Di, Rong Zhou, Hong Zhang, Pingru Su, Cong Xu, Panpan Zhou, Yushu Ge, Dan Liu, Weisheng Liu and Yu Tang
Biosensors and Bioelectronics, 2017, 92, 602
DOI: 10.1016/j.bios.2016.10.050

Detecting Cu2+ and H2O in methanol based on aggregation-induced emission fluorescent enhancement
Guo Lina, Yuanyuan Gao and Limin Han
Journal of Coordination Chemistry, 2021, 74, 1284
DOI: 10.1080/00958972.2021.1897114

Fluorescence imaging of Cu(I) in endoplasmic reticulum of live cells and tissue
Xiaowen Yan and X. Chris Le
Sci. China Chem., 2019, 62, 887
DOI: 10.1007/s11426-019-9500-6

Protein-Labeling Reagents Selectively Activated by Copper(I)
Rong Cheng, Yuki Nishikawa, Takumi Wagatsuma, Taiho Kambe, Yu-ki Tanaka, Yasumitsu Ogra, Tomonori Tamura and Itaru Hamachi
ACS Chem. Biol., 2024, 19, 1222
DOI: 10.1021/acschembio.4c00011

Fluorescent “on–off–on” probe based on copper peptide backbone for specific detection of Cu(II) and hydrogen sulfide and its applications in cell imaging, real water samples and test strips
Ping Wei, Lin Xiao, Yuting Gou, Fang He, Dagang Zhou, Yi Liu, Bin Xu, Peng Wang and Yafen Zhou
Microchemical Journal, 2022, 182, 107848
DOI: 10.1016/j.microc.2022.107848

Engineered lanthanide-doped upconversion nanoparticles for biosensing and bioimaging application
Yong Li, Chen Chen, Fangfang Liu and Jinliang Liu
Microchim Acta, 2022, 189
DOI: 10.1007/s00604-022-05180-1

Fluorescence “turn-on” sensor for highly selective recognition of Cu2+ ion and its application to living cell imaging
R. Bhaskar, Gujuluva Gangatharan Vinoth Kumar, Gandhi Sivaraman, Jegathalaprathaban Rajesh and S. Sarveswari
Inorganic Chemistry Communications, 2019, 104, 110
DOI: 10.1016/j.inoche.2019.03.041

Detection of copper in tea and water sample: A click-oriented azomethine-based 1,2,3-triazole fluorescent chemosensor with reversible INHIBIT logic gate behavior and computational aspects
Nancy George, Parveen Saini, Gurleen Singh, Riddima Singh, Gurjaspreet Singh, Pooja Malik, Harminder Singh, Gurpreet Kaur and Jandeep Singh
Journal of Molecular Structure, 2024, 1311, 138288
DOI: 10.1016/j.molstruc.2024.138288

Development of new peptide-based receptor of fluorescent probe with femtomolar affinity for Cu+ and detection of Cu+ in Golgi apparatus
Kwan Ho Jung, Eun-Taex Oh, Heon Joo Park and Keun-Hyeung Lee
Biosensors and Bioelectronics, 2016, 85, 437
DOI: 10.1016/j.bios.2016.04.101

Recent progress in the development of organic dye based near-infrared fluorescence probes for metal ions
Di Wu, Liyan Chen, Woolin Lee, Gyeongju Ko, Jun Yin and Juyoung Yoon
Coordination Chemistry Reviews, 2018, 354, 74
DOI: 10.1016/j.ccr.2017.06.011

Highly Selective Fluorescent Probe Based on 2‐(2′‐Dansylamidophenyl)‐Thiazole for Sequential Sensing of Copper(II) and Iodide Ions
Bo‐Yeon Kim, Anup Pandith, Chan Sik Cho and Hong‐Seok Kim
Bulletin Korean Chem Soc, 2019, 40, 163
DOI: 10.1002/bkcs.11663

Dye-Assembled Upconversion Nanocomposite for Luminescence Ratiometric in Vivo Bioimaging of Copper Ions
Yibing Shi, Qingyun Liu, Wei Yuan, Meng Xue, Wei Feng and Fuyou Li
ACS Appl. Mater. Interfaces, 2019, 11, 430
DOI: 10.1021/acsami.8b19961

Fluorescence-Based Recognition of Cu(II) Ion in Aqueous Solutions by Ruthenium(II) Complex Linked with Pyridine
Vikesh Kumar Singh, Anandveer Sindhu and Amit
J Anal Chem, 2023, 78, 628
DOI: 10.1134/S1061934823050143

Hydrazone Based Dual – Responsive Colorimetric and Ratiometric Chemosensor for the Detection of Cu2+/F− Ions: DNA Tracking, Practical Performance in Environmental Samples and Tooth Paste
Willsingh Anbu Durai and Andy Ramu
J Fluoresc, 2020, 30, 275
DOI: 10.1007/s10895-020-02488-0

Selective and Sensitive Fluorescence Turn‐On Detection of Cyanide Ions in Water by Post Metallization of a MOF
Debanjan Mahato, Sahel Fajal, Partha Samanta, Writakshi Mandal and Sujit K. Ghosh
ChemPlusChem, 2022, 87
DOI: 10.1002/cplu.202100426

Rapid Two-Photon Fluorescence Imaging of Monoamine Oxidase B for Diagnosis of Early-Stage Liver Fibrosis in Mice
Nannan Fan, Chuanchen Wu, Yongqing Zhou, Xin Wang, Ping Li, Zhenzhen Liu and Bo Tang
Anal. Chem., 2021, 93, 7110
DOI: 10.1021/acs.analchem.1c00815

Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases
Ece Eksin and Arzum Erdem
Micromachines, 2023, 14, 295
DOI: 10.3390/mi14020295

A near-infrared fluorescent probe for sensing cuprous ions
Meirong Yi, Jintao Zhao, Ruipeng Shen, Tao Ma, Jingwen Tu, Xinming Li, Baoxin Zhang and Jianguo Fang
Sensors and Actuators B: Chemical, 2025, 425, 136982
DOI: 10.1016/j.snb.2024.136982

A highly selective and sensitive Schiff-base based turn-on optical sensor for Cu2+ in aqueous medium and acetonitrile
Xin Wang, Wei Shi, Lei Feng, Junchi Ma, Yuqin Li, Xiangjuan Kong, Yabin Chen, Yonghai Hui and Zhengfeng Xie
Inorganic Chemistry Communications, 2017, 79, 50
DOI: 10.1016/j.inoche.2017.03.006

Highly selective sequential detection of Cu2+ and S2− using a large stokes shift peptide-based fluorescent probe and its multi-application
Yi Ren, Mengying Jia, Shiyi Xiong, Chunmei Pu, Peng Wang and Yong An
Microchemical Journal, 2025, 216, 114732
DOI: 10.1016/j.microc.2025.114732

A highly selective NIR ratiometric fluorescent probe for in situ detection of metabolized hydrazine in living cells
Qi Song, Ning Wang, Fangkun Wang, Kaizhuo Guo, Jiwei Cui, Jingcheng Hao, Yong-Qiang Zhang and Jie Jiang
Sensors and Actuators B: Chemical, 2023, 393, 134164
DOI: 10.1016/j.snb.2023.134164

Pore‐Engineered Hydrogen‐Bonded Supramolecular Fluorosensor for Ultrasensitive Determination of Copper Ions
Haiting Chen, Haoquan Huang, Huiying Xu, Tong Wu, Yanbin Xu, Xiaomin Ma, Wei Yi, Guosheng Chen, Siming Huang and Gangfeng Ouyang
Small, 2024, 20
DOI: 10.1002/smll.202308716

A New Ratiometric Lysosomal Copper(II) Fluorescent Probe To Map a Dynamic Metallome in Live Cells
Maria Laura Giuffrida, Giuseppe Trusso Sfrazzetto, Cristina Satriano, Stefania Zimbone, Gaetano A. Tomaselli, Agata Copani and Enrico Rizzarelli
Inorg. Chem., 2018, 57, 2365
DOI: 10.1021/acs.inorgchem.7b02720

A comprehensive review on recent advances in copper sensors
Tavishi Chopra, Sonakshi Sasan, Lalita Devi, Raman Parkesh and Kamal K. Kapoor
Coordination Chemistry Reviews, 2022, 470, 214704
DOI: 10.1016/j.ccr.2022.214704

Using Ligand-Accelerated Catalysis to Repurpose Fluorogenic Reactions for Platinum or Copper
Dianne Pham, Carly J. Deter, Mariah C. Reinard, Gregory A. Gibson, Kirill Kiselyov, Wangjie Yu, Vlad C. Sandulache, Claudette M. St. Croix and Kazunori Koide
ACS Cent. Sci., 2020, 6, 1772
DOI: 10.1021/acscentsci.0c00676

Monitoring nutrients in plants with genetically encoded sensors: achievements and perspectives
Mayuri Sadoine, Roberto De Michele, Milan Župunski, Guido Grossmann and Vanessa Castro-Rodríguez
Plant Physiology, 2023, 193, 195
DOI: 10.1093/plphys/kiad337

Synthesis and evaluation of fluorescein coumarin hybrid sensor for copper and fluoride ion sensing
Aruna, Prabhat Ranjan, Arunava Agarwala, Ved Prakash Verma and Rahul Shrivastava
Analytical Chemistry Letters, 2025, 15, 905
DOI: 10.1080/22297928.2025.2548317

Sequential Detection of CN- and HSO4- Anions in an Aqueous Environment Utilizing a New Colorimetric Azoimine Receptor: Mimicking Logic Gate Behaviour and a Security Keypad Lock
Khatereh Rezaeian, Hamid Khanmohammadi and Nafiseh Shabani
Australian Journal of Chemistry, 2018, 71, 389
DOI: 10.1071/CH18048

Optimizing the Readout of Lanthanide-DOTA Complexes for the Detection of Ligand-Bound Copper(I)
Jill Hanna, Christopher Allan, Charlotte Lawrence, Odile Meyer, Neil Wilson and Alison Hulme
Molecules, 2017, 22, 802
DOI: 10.3390/molecules22050802

Seeking Illumination: The Path to Chemiluminescent 1,2-Dioxetanes for Quantitative Measurements and In Vivo Imaging
Uroob Haris, Husain N. Kagalwala, Yujin Lisa Kim and Alexander R. Lippert
Acc. Chem. Res., 2021, 54, 2844
DOI: 10.1021/acs.accounts.1c00185

Characterization of a highly Al3+‐selective fluorescence probe based on naphthalimide‐Schiff base and its application to practical water samples
Kesheng Shen, Shanshan Mao, Xinkui Shi, Fei Wang, Yuling Xu, Stephen Opeyemi Aderinto and Huilu Wu
Luminescence, 2018, 33, 54
DOI: 10.1002/bio.3372

3-Pyrrolyl BODIPY Based Selective Cu2+ Ion “Off-On” Fluorescent Sensor
Panchavarnam Sabari and Mangalampalli Ravikanth
J Chem Sci, 2021, 133
DOI: 10.1007/s12039-021-01922-5

Solvent Directed Fluorometric Discrimination of Cu2+ and Ni2+ Ions by a Quinoline-Based Glucopyranosyl Derivative
Ananta Kumar Atta, Mini Loya, Nabakumar Pramanik and Pallab Pahari
SSRN Journal, 2022
DOI: 10.2139/ssrn.4131243

Different functional groups dependent fluorescent properties for ESIPT-based ABTN derivatives: A theoretical study
Zhengyi Zhang and Hua Fang
Computational and Theoretical Chemistry, 2024, 1238, 114717
DOI: 10.1016/j.comptc.2024.114717

Making Every Penny Count: Kinase Signaling Transduction, Copper Homeostasis, & Nutrient Sensing
Donita C. Brady
Journal of Molecular Biology, 2025, 437, 169089
DOI: 10.1016/j.jmb.2025.169089

Optimizing Cu(II) luminescent nanosensors by molecular engineering of the indicator dye and the encapsulation process
Klecia M. Santos, Andre Ribeiro Santos, Ivo M. Raimundo, Maria C. Moreno-Bondi and Guillermo Orellana
Sensors and Actuators B: Chemical, 2018, 255, 2367
DOI: 10.1016/j.snb.2017.09.043

Small molecule optical sensors for nickel: The quest for a universal nickel receptor
Rebecca L. Mattison, Amy A. Bowyer and Elizabeth J. New
Coordination Chemistry Reviews, 2020, 425, 213522
DOI: 10.1016/j.ccr.2020.213522

Metal ions sensing properties of some phenylquinoxaline derivatives
Mihaela Homocianu, Alina Mirela Ipate, Daniel Homocianu, Anton Airinei and Corneliu Hamciuc
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 215, 371
DOI: 10.1016/j.saa.2019.03.005

Highly selective fluorescent probe for sequential recognition of copper(II) and iodide ions
Hansol Seo, Miran An, Bo-Yeon Kim, Jun-Hyeak Choi, Aasif Helal and Hong-Seok Kim
Tetrahedron, 2017, 73, 4684
DOI: 10.1016/j.tet.2017.06.034

Near-infrared fluorescent probe for selective detection of Cu2+ in living cells and in Vivo
Zhiyang Xu, Hong Wang, Zhen Chen, Hongli Jiang and Yanqing Ge
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 216, 404
DOI: 10.1016/j.saa.2019.03.062

Advances in fluorescent probes for targeting organelles: Design strategies, applications and perspectives
Meiqing Zhu, Wenze Li, Long Sun, Zhanao Lv, Xiaofan Yang and Yi Wang
Coordination Chemistry Reviews, 2024, 512, 215893
DOI: 10.1016/j.ccr.2024.215893

Recent Advances of Optical Sensors for Copper Ion Detection
Zeynep Gerdan, Yeşeren Saylan and Adil Denizli
Micromachines, 2022, 13, 1298
DOI: 10.3390/mi13081298

Near-infrared II excited off-on fluorescent probe for molecular imaging of copper ions in Wilson disease
Rongrong Deng, Yijie Gao, Shuai Zhao, Yufei Li, Shengru He, Yanxiang Gao, Zhengqin Zhai, Jingang Zheng, Jun Nie and Yincheng Chang
Sensors and Actuators B: Chemical, 2025, 444, 138408
DOI: 10.1016/j.snb.2025.138408

Phenanthroline-Derivative Functionalized Carbon Dots for Highly Selective and Sensitive Detection of Cu2+ and S2− and Imaging inside Live Cells
Lina Zhang, Zhanwei Wang, Jingbo Zhang, Jianbo Jia, Dan Zhao and Yunchang Fan
Nanomaterials, 2018, 8, 1071
DOI: 10.3390/nano8121071

1H NMR and GC-MS Based Metabolomics Reveal Defense and Detoxification Mechanism of Cucumber Plant under Nano-Cu Stress
Lijuan Zhao, Yuxiong Huang, Jerry Hu, Hongjun Zhou, Adeyemi S. Adeleye and Arturo A. Keller
Environ. Sci. Technol., 2016, 50, 2000
DOI: 10.1021/acs.est.5b05011

From photochromism to electrochromism: New property of diarylethene BTT and its fluorescent turn-on derivative BTTO4
Jionghao Wang, Kangjun Lan, Aidong Qi, Yunjia Xu, Qi Ai, Xiaoguang Hu and Baoxiang Gao
Journal of Molecular Structure, 2026, 1359, 145559
DOI: 10.1016/j.molstruc.2026.145559

Solvent directed fluorometric discrimination of Cu2+ and Ni2+ ions by a quinoline-based glucopyranosyl derivative
Mini Loya, Nabakumar Pramanik, Pallab Pahari and Ananta Kumar Atta
Journal of Photochemistry and Photobiology A: Chemistry, 2022, 433, 114173
DOI: 10.1016/j.jphotochem.2022.114173

A new Cu2+-selective fluorescent probe with six-membered spirocyclic hydrazide and its application in cell imaging
Kun Huang, Defang Han, Xianglin Li, Mengni Peng, Xianshun Zeng, Linhai Jing and Dabin Qin
Dyes and Pigments, 2019, 171, 107701
DOI: 10.1016/j.dyepig.2019.107701

Confinement fluorescence effect (CFE): Lighting up life by enhancing the absorbed photon energy utilization efficiency of fluorophores
Bin Fang, Panpan Li, Jiamin Jiang, Wei Du, Limin Wang, Hua Bai, Bo Peng, Xiao Huang, Zhongfu An, Lin Li, Xuekang Yang, Li Fu and Wei Huang
Coordination Chemistry Reviews, 2021, 440, 213979
DOI: 10.1016/j.ccr.2021.213979

A novel peptide-based AIE-active fluorescent probe for highly selective and sensitive detection of Cu (II) ions and its applications in environmental analysis and bioimaging
Xinlin Cao, Fengqian Liu, Shiyi Xiong, Shiyi Tang, Lan Chen and Peng Wang
Journal of Molecular Structure, 2025, 1343, 142875
DOI: 10.1016/j.molstruc.2025.142875

Small Two-Photon Organic Fluorogenic Probes: Sensing and Bioimaging of Cancer Relevant Biomarkers
Amit Kumar Singh, Asha V Nair and N. D. Pradeep Singh
Anal. Chem., 2022, 94, 177
DOI: 10.1021/acs.analchem.1c04306

Human Body Performance with COVID-19 Affectation According to Virus Specification Based on Biosensor Techniques
Mohammed Jawad Ahmed Alathari, Yousif Al Mashhadany, Mohd Hadri Hafiz Mokhtar, Norhafizah Burham, Mohd Saiful Dzulkefly Bin Zan, Ahmad Ashrif A Bakar and Norhana Arsad
Sensors, 2021, 21, 8362
DOI: 10.3390/s21248362

Transition Metals Induce Quenching of Monomeric Near-Infrared Fluorescent Proteins
Haowen Zhao and Melissa L. Zastrow
Biochemistry, 2022, 61, 494
DOI: 10.1021/acs.biochem.1c00705

Electrochemiluminescence Sensor Based on TPEA‐RuMOF: For Highly Selective and Sensitive Detection of Copper Ions
Hai Shuai, Hanfeng Cui, Jie Zhang, Huiting Hu, Qian Long, Xiaocui Yin, Fusheng Liao, Hao Fan, Zhiqiang Liu and Bo Wu
ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202401018

Medicago truncatula copper transporter 1 (MtCOPT1) delivers copper for symbiotic nitrogen fixation
Marta Senovilla, Rosario Castro‐Rodríguez, Isidro Abreu, Viviana Escudero, Igor Kryvoruchko, Michael K. Udvardi, Juan Imperial and Manuel González‐Guerrero
New Phytologist, 2018, 218, 696
DOI: 10.1111/nph.14992

Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools
Aidan T. Pezacki, Carson D. Matier, Xingxing Gu, Eric Kummelstedt, Sarah E. Bond, Laura Torrente, Kelly L. Jordan-Sciutto, Gina M. DeNicola, Timothy A. Su, Donita C. Brady and Christopher J. Chang
Proc. Natl. Acad. Sci. U.S.A., 2022, 119
DOI: 10.1073/pnas.2202736119

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
Léo Aubert, Neethi Nandagopal, Zachary Steinhart, Geneviève Lavoie, Sami Nourreddine, Jacob Berman, Marc K. Saba-El-Leil, David Papadopoli, Sichun Lin, Traver Hart, Graham Macleod, Ivan Topisirovic, Louis Gaboury, Christoph J. Fahrni, Daniel Schramek, Sylvain Meloche, Stephane Angers and Philippe P. Roux
Nat Commun, 2020, 11
DOI: 10.1038/s41467-020-17549-y

Porphyrinic Probe for Fluorescence “Turn-On” Monitoring of Cu+ in Aqueous Buffer and Mitochondria
Xiao-Qin Yi, Yuan-Fan He, Yu-Sheng Cao, Wang-Xing Shen and Yuan-Yuan Lv
ACS Sens., 2019, 4, 856
DOI: 10.1021/acssensors.8b01240

Fluorometric detection of Cu2+ and Ni2+ by a quinoline-based glucopyranose derivative via the excimer of quinoline subunit
Mini Loya, Samiul Islam Hazarika, Pallab Pahari and Ananta Kumar Atta
Journal of Molecular Structure, 2021, 1241, 130634
DOI: 10.1016/j.molstruc.2021.130634

Smartphone-assisted colorimetric and fluorescent dual-functional peptide-based probe for multianalyte visual detection in 100% aqueous media, living cells and test strips
Lin Xiao, Ping Wei, Fang He, Yuting Gou, Jiang Zhou, Peng Wang and Jiang Wu
Journal of Molecular Structure, 2023, 1274, 134556
DOI: 10.1016/j.molstruc.2022.134556

A new “on-off-on” fluorescent probe containing triarylimidazole chromophore to sequentially detect copper and sulfide ions
Yongpeng Wang, Dali Qiu, Mengnan Li, Yijiang Liu, Hongbiao Chen and Huaming Li
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017, 185, 256
DOI: 10.1016/j.saa.2017.05.061

Transition Metals Coordination by Bis-imidazole-calix[4]arene Ligands with and Without Pyrene Units Grafted at the Large Rim
Ivana Nikšić-Franjić, Dijana Pavlović Saftić, Vilko Smrečki, Benoit Colasson, Olivia Reinaud, Ivo Piantanida and Aleksandar Višnjevac
IJMS, 2024, 25, 11314
DOI: 10.3390/ijms252011314

Carbohydrate-modified simple efficient fluorometric probe for sensing Cu2+ions in aqueous solution
Suprava Ghosh, Mini Loya, Santanab Giri, Nabakumar Pramanik and Ananta Kumar Atta
Journal of Molecular Structure, 2025, 1320, 139662
DOI: 10.1016/j.molstruc.2024.139662

A large Stokes shift, sequential, colorimetric fluorescent probe for sensing Cu2+/S2- and its applications
Ji-Zhen Li, Tao-Hua Leng, Zhi-Qiang Wang, Li Zhou, Xue-Qing Gong, Yong-Jia Shen and Cheng-Yun Wang
Journal of Photochemistry and Photobiology A: Chemistry, 2019, 373, 146
DOI: 10.1016/j.jphotochem.2019.01.006

FRET-based ratiometric fluorescent probe for Cu 2+ with a new indolizine fluorophore
Xiaoling Zheng, Ruixue Ji, Xiaoqun Cao and Yanqing Ge
Analytica Chimica Acta, 2017, 978, 48
DOI: 10.1016/j.aca.2017.04.048

Chalcogen-based fluorescent probes for metal ion detection: Principles, applications, and design strategies
Yuning Liu, Yandong Zhang, Xiaowei Jiang, Jing An, Jiyun Dai, Ying Ying, Runhang Li, Weihong Wang, Li Liu and Hongxin Wu
Coordination Chemistry Reviews, 2024, 513, 215896
DOI: 10.1016/j.ccr.2024.215896

A dual-response ratiometric near-infrared fluorescence probe based on cyanine platform for Cu2+ detection and its imaging in vitro and vivo
Zhijian Chang, Shumeng Li, Jia-Hai Ye, Fuyan Lin, Yuncong Chen, Zijian Guo and Weijiang He
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 125115
DOI: 10.1016/j.saa.2024.125115

A chromone derivative as a colorimetric and “ON-OFF-ON” fluorescent probe for highly sensitive and selective detection of Cu2+ and S2−
Cong Liu, Limei Tian, Kui Liu, Jia Xue, Long Fan, Tianrong Li and Zheng-yin Yang
Inorganica Chimica Acta, 2021, 519, 120280
DOI: 10.1016/j.ica.2021.120280

Molecular Design Strategies Enabling Activity-Based Sensing and Labeling as a Platform for Probing Enzyme Activity, Redox Regulation, and Transition-Metal Signaling
Hanna I. Humpel, Alexander P. Luancing, Benjamin H. Shostak and Marco S. Messina
Bioconjugate Chem., 2026, 37, 494
DOI: 10.1021/acs.bioconjchem.5c00662

Dynamic Photoacoustic Imaging of Mobile Cu(II) in Vivo via Catalytic Radical Cation Formation
Zhiyong Jiang, Qian Sun, Xiaoqing Wang, Yuncong Chen, Fang Liu, Jing Zhao, Zijian Guo and Zhipeng Liu
Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202500149

Intracellular Biotransformation of Cu(II)/Cu(I) Explained High Cu Toxicity to Phytoplankton Chlamydomonas reinhardtii
Xiangrui Wang and Wen-Xiong Wang
Environ. Sci. Technol., 2021, 55, 14772
DOI: 10.1021/acs.est.1c05408

Lanthanide‐Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Lei Zhang, André F. Martins, Piyu Zhao, Yunkou Wu, Gyula Tircsó and A. Dean Sherry
Angewandte Chemie, 2017, 129, 16853
DOI: 10.1002/ange.201707959

Near-infrared ratiometric fluorescent detection of arginine in lysosome with a new hemicyanine derivative
Mingming Yu, Weiwei Du, Haixia Li, Hongyan Zhang and Zhanxian Li
Biosensors and Bioelectronics, 2017, 92, 385
DOI: 10.1016/j.bios.2016.10.090

Salicylaldehyde built fluorescent probe for dual sensing of Al3+, Zn2+ ions: Applications in latent fingerprint, bio-imaging & real sample analysis
T. Johny Dathees, G. Narmatha, G. Prabakaran, Sonai Seenithurai, Jeng-Da Chai, Raju Suresh Kumar, J. Prabhu and R. Nandhakumar
Food Chemistry, 2024, 441, 138362
DOI: 10.1016/j.foodchem.2024.138362

Novel Schiff base decorated cyclotriphosphazene chemosensors for Fe and Cu ions detection
Elif Şenkuytu and Esra Tanrıverdi Eçik
Journal of Molecular Structure, 2025, 1321, 140100
DOI: 10.1016/j.molstruc.2024.140100

A selective colorimetric and red-emitting fluorometric probe for sequential detection of Cu2+ and H2S
Yuesong Hu, Jie Kang, Panpan Zhou, Xiao Han, Jinyu Sun, Shudi Liu, Liangwei Zhang and Jianguo Fang
Sensors and Actuators B: Chemical, 2018, 255, 3155
DOI: 10.1016/j.snb.2017.09.140

“On–off–on” pyrene‐based fluorescent chemosensor for the selective recognition of Cu2+ and S2− ions and its utilization in live cell imaging
Dhivya Rajasekaran, Kavitha Venkatachalam and Viswanathamurthi Periasamy
Applied Organom Chemis, 2020, 34
DOI: 10.1002/aoc.5342

Optical Biosensors for Virus Detection: Prospects for SARS‐CoV‐2/COVID‐19
Hemanth Maddali, Catherine E. Miles, Joachim Kohn and Deirdre M. O'Carroll
ChemBioChem, 2021, 22, 1176
DOI: 10.1002/cbic.202000744

Dysfunction in atox-1 and ceruloplasmin alters labile Cu levels and consequently Cu homeostasis in C. elegans
Ann-Kathrin Weishaupt, Karsten Lamann, Elke Tallarek, Aidan T. Pezacki, Carson D. Matier, Tanja Schwerdtle, Michael Aschner, Christopher J. Chang, Stephen R. Stürzenbaum and Julia Bornhorst
Front. Mol. Biosci., 2024, 11
DOI: 10.3389/fmolb.2024.1354627

Hydrogel Interferometry for Ultrasensitive and Highly Selective Chemical Detection
Mo Sun, Ruobing Bai, Xingyun Yang, Jiaqi Song, Meng Qin, Zhigang Suo and Ximin He
Advanced Materials, 2018, 30
DOI: 10.1002/adma.201804916

A novel route of intercellular copper transport and detoxification in oyster hemocytes
Yali Luo, Aidan T. Pezacki, Carson D. Matier and Wen-Xiong Wang
Journal of Hazardous Materials, 2024, 476, 135003
DOI: 10.1016/j.jhazmat.2024.135003

In Cellulo Mapping of Subcellular Localized Bilirubin
Jong-Seok Park, Eunju Nam, Hye-Kyeong Lee, Mi Hee Lim and Hyun-Woo Rhee
ACS Chem. Biol., 2016, 11, 2177
DOI: 10.1021/acschembio.6b00017

Synthesis and Application of Pyrene‐Based Fluorescent Probe for the Continuous Detection of Cu2+ and Picric Acid
Canyao Wu, Yanchao Yu, Jun You, Sijia Chen, Wenju Wu and Yifang Liang
Luminescence, 2025, 40
DOI: 10.1002/bio.70300

An “off-on” fluorescent sensor for copper ion using graphene quantum dots based on oxidation of l-cysteine
Longhua Ding, Zhongyao Zhao, Dongjun Li, Xue Wang and Jialin Chen
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 214, 320
DOI: 10.1016/j.saa.2019.02.048

Intracellular Distribution of Fluorescent Copper and Zinc Bis(thiosemicarbazonato) Complexes Measured with Fluorescence Lifetime Spectroscopy
James L. Hickey, Janine L. James, Clare A. Henderson, Katherine A. Price, Alexandra I. Mot, Gojko Buncic, Peter J. Crouch, Jonathan M. White, Anthony R. White, Trevor A. Smith and Paul S. Donnelly
Inorg. Chem., 2015, 54, 9556
DOI: 10.1021/acs.inorgchem.5b01599

Interfacially Super‐Assembled Benzimidazole Derivative‐Based Mesoporous Silica Nanoprobe for Sensitive Copper (II) Detection and Biosensing in Living Cells
Chenchen Xing, Jianlin Deng, Wenlong Fu, Jichao Li, Lijie Xu, Ruihao Sun, Dan Wang, Chengwen Li, Kang Liang, Meng Gao and Biao Kong
Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202103642

Polymerizing dopamine onto Q-graphene scaffolds towards the fluorescent nanocomposites with high aqueous stability and enhanced fluorescence for the fluorescence analysis and imaging of copper ions
Minmin Dong, Chunli Liu, Shuying Li, Rui Li, Yuchun Qiao, Liyan Zhang, Wei Wei, Wei Qi and Hua Wang
Sensors and Actuators B: Chemical, 2016, 232, 234
DOI: 10.1016/j.snb.2016.03.142

Simultaneous Detection of Cu2+ and Hg2+ via Two Mutually Independent Sensing Pathways of Biimidazole Push–Pull Dye
Nilanjan Dey, Jiří Kulhánek, Filip Bureš and Santanu Bhattacharya
J. Org. Chem., 2019, 84, 1787
DOI: 10.1021/acs.joc.8b02591

A novel ratiometric and reversible fluorescence probe with a large Stokes shift for Cu2+ based on a new clamp-on unit
Yun-Hui Zhao, Yueyang Luo, Han Wang, Haipeng Wei, Tao Guo, Hailong Tan, Lin Yuan and Xiao-Bing Zhang
Analytica Chimica Acta, 2019, 1065, 134
DOI: 10.1016/j.aca.2019.03.029

A Simple Turn-off Schiff Base Fluorescent Sensor for Copper (II) Ion and Its Application in Water Analysis
Xing Zhang, Ling-Yi Shen, Qi-Long Zhang, Xian-Jiong Yang, Ya-Li Huang, Carl Redshaw and Hong Xu
Molecules, 2021, 26, 1233
DOI: 10.3390/molecules26051233

Ratiometric detection of Cu+ in aqueous buffered solutions and in live cells using fluorescent peptidyl probe to mimic the binding site of the metalloprotein for Cu+
Pramod Kumar Mehta, Eun-Taex Oh, Heon Joo Park and Keun-Hyeung Lee
Sensors and Actuators B: Chemical, 2018, 256, 393
DOI: 10.1016/j.snb.2017.10.087

Sensitive and selective detection of Cu(II) ion: A new effective 1,8‐naphthalimide‐based fluorescence ‘turn off’ sensor
Guozhen Huang, Chuang Li, Xintong Han, Stephen Opeyemi Aderinto, Kesheng Shen, Shanshan Mao and Huilu Wu
Luminescence, 2018, 33, 660
DOI: 10.1002/bio.3461

Sulfur‐Doped Carbon Dots as a Highly Selective and Sensitive Fluorescent Probe for Copper Ion Detection in Biological Systems
Minyoung Jin, Sanghee Lee, Su been Lim, Minyoung Lee, Jungwon Park, Hyun‐Do Jung, Min‐Ho Kang and Kun Na
Small, 2025, 21
DOI: 10.1002/smll.202410765

A Smartphone‐Assisted Sensitive, Selective and Reversible Recognition of Copper Ions in an Aqueous Medium
Arvind Kumar, Anuradha Bera and Satish Kumar
ChemistrySelect, 2020, 5, 1020
DOI: 10.1002/slct.201904399

Sensing Zn2+ in Aqueous Solution with a Fluorescent Scorpiand Macrocyclic Ligand Decorated with an Anthracene Bearing Tail
Matteo Savastano, Matteo Fiaschi, Giovanni Ferraro, Paola Gratteri, Palma Mariani, Antonio Bianchi and Carla Bazzicalupi
Molecules, 2020, 25, 1355
DOI: 10.3390/molecules25061355

Carbohydrate CuAAC click chemistry for therapy and diagnosis
Xiao-Peng He, Ya-Li Zeng, Yi Zang, Jia Li, Robert A. Field and Guo-Rong Chen
Carbohydrate Research, 2016, 429, 1
DOI: 10.1016/j.carres.2016.03.022

Coumarin-based colorimetric fluorescent chemical sensors for highly selectively and accurately detect Cu2+ ions in water and living cells
Qian Sun, Lu Ren, Jing Wang, Kun Bai, Chang Liu, Yanqi Liu and Dawei Zhang
Inorganica Chimica Acta, 2026, 590, 122981
DOI: 10.1016/j.ica.2025.122981

A selective proton transfer optical sensor for copper II based on chelation enhancement quenching effect (CHEQ)
Luís Gustavo Teixeira Alves Duarte, Felipe Lange Coelho, José Carlos Germino, Gabriela Gamino da Costa, Jônatas Faleiro Berbigier, Fabiano Severo Rodembusch and Teresa Dib Zambon Atvars
Dyes and Pigments, 2020, 181, 108566
DOI: 10.1016/j.dyepig.2020.108566

Metal‐Catalyzed Abiotic Cleavage of C═C Bonds for Effective Fluorescence Imaging of Cu(II) and Fe(III) in Living Systems
Chunfei Wang, Dandan Chen, Zixiang Wei, Jingyun Tan, Changfeng Wu and Xuanjun Zhang
Advanced Science, 2025, 12
DOI: 10.1002/advs.202412407

Selective Detection of Cu+ Ions in Live Cells via Fluorescence Lifetime Imaging Microscopy
Martin Priessner, Peter A. Summers, Benjamin W. Lewis, Magdalena Sastre, Liming Ying, Marina K. Kuimova and Ramon Vilar
Angew Chem Int Ed, 2021, 60, 23148
DOI: 10.1002/anie.202109349

Colorimetric copper ion sensing in solution phase and on paper substrate based on catalytic decomposition of S-nitrosothiol
Yu Cui, Xuewei Wang, Qi Zhang, Hao Zhang, Huahua Li and Mark Meyerhoff
Analytica Chimica Acta, 2019, 1053, 155
DOI: 10.1016/j.aca.2018.11.050

Adenine-stabilized carbon dots for highly sensitive and selective sensing of copper(II) ions and cell imaging
Yaxin Mu, Qianfen Zhuang, Saipeng Huang, Mingyue Hu, Yong Wang and Yongnian Ni
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 239, 118531
DOI: 10.1016/j.saa.2020.118531

Dynamic Regulation of Intracellular Labile Cu(I)/Cu(II) Cycle in Microalgae Chlamydomonas reinhardtii: Disrupting the Balance by Cu Stress
Shaoxi Deng and Wen-Xiong Wang
Environ. Sci. Technol., 2024, 58, 5255
DOI: 10.1021/acs.est.3c10257

Bile acid based receptors for multiple metal ion recognition
Aradhana Nayal, Pradeep Kumar Muwal and Pramod S. Pandey
Tetrahedron, 2019, 75, 1968
DOI: 10.1016/j.tet.2019.02.017

Rational development of a peptide-based probe for fluorescence and colorimetric dual-mode detection of Cu2+ and S2− ions: Real application in cell imaging and test strips
Maoyue Zheng, Miao Zhou, Shirui Xue, Bo Chen and Peng Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 302, 123006
DOI: 10.1016/j.saa.2023.123006

A fluorescent probe for the detection of Cu(II) in water and tumor cells
Di Qian, Zheng Wang, Zhongxin Xiao and Chen-Jie Fang
Inorganic Chemistry Communications, 2021, 126, 108471
DOI: 10.1016/j.inoche.2021.108471

Networking Nanoswitches for ON/OFF Control of Catalysis
Nikita Mittal, Susnata Pramanik, Indrajit Paul, Soumen De and Michael Schmittel
J. Am. Chem. Soc., 2017, 139, 4270
DOI: 10.1021/jacs.6b12951

An AIE active anthracene-based Schiff base probe for “turn-on” detection of Cu2+ ions: Demonstrations with nanostructural investigations, DFT, cellular imaging, and real water analysis
Muthaiah Shellaiah, Hsuan-Chang Chen, Kamlesh Awasthi, Basheer Aazaad, Kien Wen Sun, Nobuhiro Ohta and Ming-Chang Lin
Journal of Molecular Structure, 2024, 1301, 137347
DOI: 10.1016/j.molstruc.2023.137347

Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism
Clive Yik-Sham Chung, Jessica M. Posimo, Sumin Lee, Tiffany Tsang, Julianne M. Davis, Donita C. Brady and Christopher J. Chang
Proc. Natl. Acad. Sci. U.S.A., 2019, 116, 18285
DOI: 10.1073/pnas.1904610116

Copper distribution in breast cancer cells detected by time-of-flight secondary ion mass spectrometry with delayed extraction methodology
Stéphanie Blockhuys, Per Malmberg and Pernilla Wittung-Stafshede
Biointerphases, 2018, 13
DOI: 10.1116/1.5053814

Current and Future of “Turn‐On” Based Small‐Molecule Copper Probes for Cuproptosis
Ting‐En Peng, Feng Qiu, Yunwei Qu, Changmin Yu, Xiamin Cheng and Lin Li
ChemistryOpen, 2023, 12
DOI: 10.1002/open.202300078

A water-soluble fluorescence “turn on” chemosensor for Cu2+ signaling: A combined photophysical and cell imaging study
Xin-Yi Wang, Zi-Kai Yu, Jin-Hao Wang, Jie Shen, Ying-Mei Lu, Wang-Xing Shen, Yuan-Yuan Lv and Xiao-Yi Sun
Journal of Photochemistry and Photobiology A: Chemistry, 2018, 357, 49
DOI: 10.1016/j.jphotochem.2018.02.020

Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper
Sumin Lee, Clive Yik-Sham Chung, Pei Liu, Laura Craciun, Yuki Nishikawa, Kevin J. Bruemmer, Itaru Hamachi, Kaoru Saijo, Evan W. Miller and Christopher J. Chang
J. Am. Chem. Soc., 2020, 142, 14993
DOI: 10.1021/jacs.0c05727

Recent Advances in Fluorescence Imaging of Bioactive Molecules in Neurons and in Vivo
Xin WANG, Ping LI, Wen ZHANG and Bo TANG
Chinese Journal of Analytical Chemistry, 2019, 47, 1537
DOI: 10.1016/S1872-2040(19)61191-6

A unique benzimidazole-naphthalene hybrid molecule for independent detection of Zn2+ and N3− ions: Experimental and theoretical investigations
Sabyasachi Ta, Sudipta Das, Milan Ghosh, Mahuya Banerjee, Sumit Kumar Hira, Partha Pratim Manna and Debasis Das
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 209, 170
DOI: 10.1016/j.saa.2018.10.006

A Novel Water Soluble Bipyrazolic Tripod Azoic Dye as Chemosensor for Copper (II) in Aqueous Solution
Jalal Isaad, Tarik Harit, Haad Bessbousse, Ahmida El Achari and Fouad Malek
Chemistry Africa, 2019, 2, 29
DOI: 10.1007/s42250-018-0028-2

Coumarin‐Based Reversible Fluorescent Chemosensors for the Sequential Detection of Copper and Citrate Ions
Devender Singh, Annan Ibrahim and Rajeev Gupta
ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202203326

A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer
Marco S. Messina, Laura Torrente, Aidan T. Pezacki, Hanna I. Humpel, Erin L. Li, Sophia G. Miller, Odette Verdejo-Torres, Teresita Padilla-Benavides, Donita C. Brady, David W. Killilea, Alison N. Killilea, Martina Ralle, Nathan P. Ward, Jun Ohata, Gina M. DeNicola and Christopher J. Chang
Proc. Natl. Acad. Sci. U.S.A., 2025, 122
DOI: 10.1073/pnas.2412816122

Fluorescent detection of Cu(II) by chitosan-based AIE bioconjugate
Ya-lan Liu, Zheng-ke Wang, Wei Qin, Qiao-ling Hu and Ben Zhong Tang
Chin J Polym Sci, 2017, 35, 365
DOI: 10.1007/s10118-017-1876-y

Cu(I) chelators: Useful tools to reveal and control Cu(I) homeostasis and toxicity
Charlène Esmieu, Sarah Hostachy and Christelle Hureau
Coordination Chemistry Reviews, 2025, 539, 216684
DOI: 10.1016/j.ccr.2025.216684

A novel chromene acyl hydrazone Schiff base organogel with colorimetric Cu2+ responsive
Yun-Shang Yang, Li-Bin Wang, Chuan Liang, Fu-Nian Wang, Ying-peng Zhang and Ji-Jun Xue
J IRAN CHEM SOC, 2024, 21, 1141
DOI: 10.1007/s13738-024-02986-z

Metalloneurochemistry and the Pierian Spring: ‘Shallow Draughts Intoxicate the Brain’
Jacob M. Goldberg, Andrei Loas and Stephen J. Lippard
Israel Journal of Chemistry, 2016, 56, 791
DOI: 10.1002/ijch.201600034

ФЛУОРЕСЦЕНТНЫЕ ХЕМОСЕНСОРЫ НА ОСНОВЕ ИМИНОВ 4-ФОРМИЛ-3-ГИДРОКСИ-2-НАФТОЙНОЙ КИСЛОТЫ, "Наука юга России"
Е.Н. Шепеленко, В.А. Подшибякин, И.В. Дубоносова, О.Ю. Карлутова, А.Д. Дубоносов and В.А. Брень
Science in the South of Russia, 2023, 11
DOI: 10.7868/25000640230102

A covalent targeted small-molecule probe for fluorescence and photoacoustic dual-modality imaging of Cu(I) in tumors
Hang Liu, Qian Sun, Mengxi Dong, Xiaoqing Wang and Zhipeng Liu
Chinese Chemical Letters, 2025, 111655
DOI: 10.1016/j.cclet.2025.111655

Novel Fluorescence Probe toward Cu2+ Based on Fluorescein Derivatives and Its Bioimaging in Cells
Xin Leng, Du Wang, Zhaoxiang Mi, Yuchen Zhang, Bingqin Yang and Fulin Chen
Biosensors, 2022, 12, 732
DOI: 10.3390/bios12090732

A novel fluorescence “on-off-on” peptidyl probe for highly selective and consecutive detection of Cu2+ and glyphosate and its multi-functional applications
Mengying Jia, Yi Ren, Shiyi Xiong, Shiyang Li, Peng Wang and Chengqing Zhao
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 346, 126942
DOI: 10.1016/j.saa.2025.126942

Inorganic Chemistry Approaches to Activity-Based Sensing: From Metal Sensors to Bioorthogonal Metal Chemistry
Diana A. Iovan, Shang Jia and Christopher J. Chang
Inorg. Chem., 2019, 58, 13546
DOI: 10.1021/acs.inorgchem.9b01221

A smart low-molecular-mass naphthalene-pyrazoline gelator: Gelation behavior and selective fluorescent detection Cu2+
Ying-Peng Zhang, Wei-Ya Niu, Yun-Shang Yang, Zu-Feng Zhang, Yi-Zhen Yuan, Hui-Chen Guo and Hong-Rui Zhang
Journal of Molecular Liquids, 2023, 387, 122653
DOI: 10.1016/j.molliq.2023.122653

Connecting copper and cancer: from transition metal signalling to metalloplasia
Eva J. Ge, Ashley I. Bush, Angela Casini, Paul A. Cobine, Justin R. Cross, Gina M. DeNicola, Q. Ping Dou, Katherine J. Franz, Vishal M. Gohil, Sanjeev Gupta, Stephen G. Kaler, Svetlana Lutsenko, Vivek Mittal, Michael J. Petris, Roman Polishchuk, Martina Ralle, Michael L. Schilsky, Nicholas K. Tonks, Linda T. Vahdat, Linda Van Aelst, Dan Xi, Peng Yuan, Donita C. Brady and Christopher J. Chang
Nat Rev Cancer, 2022, 22, 102
DOI: 10.1038/s41568-021-00417-2

Stage specific effects of soluble copper and copper oxide nanoparticles during sea urchin embryo development and their relation to intracellular copper uptake
Cristina Torres-Duarte, Karla M. Ramos-Torres, René Rahimoff and Gary N. Cherr
Aquatic Toxicology, 2017, 189, 134
DOI: 10.1016/j.aquatox.2017.05.008

Discerning the Chemistry in Individual Organelles with Small‐Molecule Fluorescent Probes
Wang Xu, Zebing Zeng, Jian‐Hui Jiang, Young‐Tae Chang and Lin Yuan
Angew Chem Int Ed, 2016, 55, 13658
DOI: 10.1002/anie.201510721

Increased Cd2+ biosorption capability of Aspergillus nidulans elicited by crpA deletion
Imre Boczonádi, Zsófia Török, Ágnes Jakab, Gábor Kónya, Klaudia Gyurcsó, Edina Baranyai, Zoltán Szoboszlai, Boglárka Döncző, István Fábián, Éva Leiter, Mi‐Kyung Lee, László Csernoch, Jae‐Hyuk Yu, Zsófia Kertész, Tamás Emri and István Pócsi
J Basic Microbiol, 2020, 60, 574
DOI: 10.1002/jobm.202000112

A Novel Calix[4]Crown-Based 1,3,4-Oxadiazole as a Fluorescent Chemosensor for Copper(II) Ion Detection
Chun Sun, Siyi Du, Tianze Zhang and Jie Han
Front. Chem., 2021, 9
DOI: 10.3389/fchem.2021.766442

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells
M. Thomas Morgan, Daisy Bourassa, Shefali Harankhedkar, Adam M. McCallum, Stephanie A. Zlatic, Jenifer S. Calvo, Gabriele Meloni, Victor Faundez and Christoph J. Fahrni
Proc. Natl. Acad. Sci. U.S.A., 2019, 116, 12167
DOI: 10.1073/pnas.1900172116

A nano-molar fluorescent turn-on probe for copper(II) detection in living cells
Ling-Fang Wei, Chong-Yan Chen, Chia-Kai Lai, Natesan Thirumalaivasan and Shu-Pao Wu
Methods, 2019, 168, 18
DOI: 10.1016/j.ymeth.2019.04.023

Carbazole-thiophene based fluorescent probe for selective detection of Cu2+ and its live cell imaging
Haifei Wang, Panpan Wang, Liangfeng Niu, Chunhui Liu, Yingzhe Xiao, Ying Tang and Yao Chen
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 278, 121257
DOI: 10.1016/j.saa.2022.121257

Dual sensing of copper ion and chromium (VI) oxyanions by benzotriazole functionalized UiO-66 metal-organic framework in aqueous media
Aasif Helal, M. Nasiruzzaman Shaikh and Md. Abdul Aziz
Journal of Photochemistry and Photobiology A: Chemistry, 2020, 389, 112238
DOI: 10.1016/j.jphotochem.2019.112238

Embedding carbon dots and gold nanoclusters in metal-organic frameworks for ratiometric fluorescence detection of Cu2+
Qingqing Tan, Ruirui Zhang, Guoyan Zhang, Xiaoya Liu, Fengli Qu and Limin Lu
Anal Bioanal Chem, 2020, 412, 1317
DOI: 10.1007/s00216-019-02353-5

A reaction-based near-infrared fluorescent sensor for Cu2+ detection in aqueous buffer and its application in living cells and tissues imaging
Huatang Zhang, Ling Feng, Yin Jiang, Yin-Ting Wong, Yonghe He, Guansheng Zheng, Jun He, Yi Tan, Hongyan Sun and Derek Ho
Biosensors and Bioelectronics, 2017, 94, 24
DOI: 10.1016/j.bios.2017.02.037

Synthesis and application of methylthio-substituted BODIPYs/aza-BODIPYs
Xin-Dong Jiang, Xin Liu, Tao Fang and Changliang Sun
Dyes and Pigments, 2017, 146, 438
DOI: 10.1016/j.dyepig.2017.07.038

Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Paula Guerrero‐López, Jose I. Garcia‐Peiro, Felipe Hornos, Jose L. Hueso, Jesus Santamaria and J. Manuel Garcia‐Aznar
Adv Healthcare Materials, 2026
DOI: 10.1002/adhm.202505120

A dual-signals fluorometric and colorimetric peptide-based probe for Cu(II) and glyphosate detection and its application for bioimaging and water testing
Shiyang Li, Chunmei Pu, Xinlin Cao, Maoyue Zheng, Weiliang Deng, Peng Wang and Jiang Wu
Science of The Total Environment, 2024, 945, 174163
DOI: 10.1016/j.scitotenv.2024.174163

Copper-based reactions in analyte-responsive fluorescent probes for biological applications
Ho Yu Au-Yeung, Chung Ying Chan, Ka Yan Tong and Zuo Hang Yu
Journal of Inorganic Biochemistry, 2017, 177, 300
DOI: 10.1016/j.jinorgbio.2017.07.001

A Colorimetric and Long‐Wavelength “Turn‐On” Fluorescent Probe for Copper Ions Detection with High Selectivity and Sensitivity
Xiaodan Zeng, Song Gao, Cheng Jiang, Xing Jin, Mingshuo Ma, Zhigang Liu and Jie Chen
ChemistrySelect, 2021, 6, 6619
DOI: 10.1002/slct.202101520

Azobenzene disperse dye-based colorimetric probe for naked eye detection of Cu2+ in aqueous media: Spectral properties, theoretical insights, and applications
Yuan Zhang, Yu-Tong Wang, Xiao-Xue Kang, Meng Ge, Hui-Yan Feng, Jiao Han, De-Hui Wang and De-Zhi Zhao
Journal of Photochemistry and Photobiology A: Chemistry, 2018, 356, 652
DOI: 10.1016/j.jphotochem.2017.07.049

Simultaneous Imaging of Cu+ and Cu2+ in Neural Cells Using DNAzyme Probes Reveals Mechanistic Link Between Copper Redox Imbalance and Amyloid Pathology
Xiangli Shao, Zhenglin Yang, Zhihao Xu, Weijie Guo, Whitney Lewis, Boyi Gan and Yi Lu
Angewandte Chemie, 2026, 138
DOI: 10.1002/ange.202524237

Divinyl BODIPY derivative: Synthesis, photophysical properties, crystal structure, photostability and bioimaging
Liutao Yang, Ying Liu, Wei Liu, Chunping Ma, Chun Zhang and Yang Li
Bioorganic & Medicinal Chemistry Letters, 2015, 25, 5716
DOI: 10.1016/j.bmcl.2015.10.091

Shewanella oneidensisas a living electrode for controlled radical polymerization
Gang Fan, Christopher M. Dundas, Austin J. Graham, Nathaniel A. Lynd and Benjamin K. Keitz
Proc. Natl. Acad. Sci. U.S.A., 2018, 115, 4559
DOI: 10.1073/pnas.1800869115

A dual-functional peptidyl probe for fluorescent and colorimetric detection of copper(II) ions and chlortetracycline hydrochloride
Shiyang Li, Chunmei Pu, Xinlin Cao, Mengying Jia and Peng Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 348, 127217
DOI: 10.1016/j.saa.2025.127217

Exciplex formation as an approach to selective Copper(II) fluorescent sensors
Bruna B. Correia, Thomas R. Brown, Joseph H. Reibenspies, Hee-Seung Lee and Robert D. Hancock
Inorganica Chimica Acta, 2020, 506, 119544
DOI: 10.1016/j.ica.2020.119544

Carbon dots fabricated by solid-phase carbonization using p-toluidine and l-cysteine for sensitive detection of copper
Zhi Li, Qingxiang Zhou, Shuangying Li, Menghua Liu, Yanhui Li and Chunmao Chen
Chemosphere, 2022, 308, 136298
DOI: 10.1016/j.chemosphere.2022.136298

Label-free multimodal analysis of copper ions at below permissible exposure limit in the aqueous medium
Bimal Chettri, Rikitha S Fernandes, Satadru Jha and Nilanjan Dey
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 308, 123620
DOI: 10.1016/j.saa.2023.123620

Binding- and activity-based small molecule fluorescent probes for the detection of Cu+, Cu2+, Fe2+ and Fe3+ in biological systems
Yongqing Zhou, Xiaofeng Yang, Won Jun Jang, Mei Yan and Juyoung Yoon
Coordination Chemistry Reviews, 2025, 522, 216201
DOI: 10.1016/j.ccr.2024.216201

Si-rhodamine based water-soluble fluorescent probe for bioimaging of Cu+
Xiaoyun Chai, Weiwei Zhu, Qingguo Meng and Ting Wang
Chinese Chemical Letters, 2021, 32, 210
DOI: 10.1016/j.cclet.2020.11.032

An activatable chemiluminescent probe for selective and portable quantification of copper ions in food and environmental samples
Yue Wang, Shengjie Huang, Wenjing Wang, Jiaheng Zhang, Lingli Bu and Jun Li
Microchemical Journal, 2026, 225, 118021
DOI: 10.1016/j.microc.2026.118021

Highly selective sequential recognition of Cu2+ and Cys based on large absorption band shift
Xiaotong Li, Kaimei Fan, Xujian Zhang, Luyao Wang, Baohan Qu and Lihua Lu
Microchemical Journal, 2019, 146, 486
DOI: 10.1016/j.microc.2019.01.045

Photocatalytic fuel cell self-powered sensor for Cu2+ detection in water and soil: Signal amplification of biomass induced carbon-rich carbon nitride photoanode
Yun Chen, Daijie Deng, Pengcheng Yan, Yunfan Jia, Li Xu, Junchao Qian, Huaming Li and Henan Li
Sensors and Actuators B: Chemical, 2023, 395, 134501
DOI: 10.1016/j.snb.2023.134501