Active Sites of O2-Evolving Chlorite Dismutases Probed by Halides and Hydroxides and New Iron–Ligand Vibrational Correlations

Zachary Geeraerts, Kenton R. Rodgers, Jennifer L. DuBois and Gudrun S. Lukat-Rodgers

Biochemistry, 2017, 56, 4509
DOI: 10.1021/acs.biochem.7b00572

A Dimeric Chlorite Dismutase Exhibits O2-Generating Activity and Acts as a Chlorite Antioxidant in Klebsiella pneumoniae MGH 78578

Arianna I. Celis, Zachary Geeraerts, David Ngmenterebo, Melodie M. Machovina, Richard C. Kurker, Kumar Rajakumar, Anabella Ivancich, Kenton R. Rodgers, Gudrun S. Lukat-Rodgers and Jennifer L. DuBois

Biochemistry, 2015, 54, 434
DOI: 10.1021/bi501184c

Peroxidase-Type Reactions Suggest a Heterolytic/Nucleophilic O–O Joining Mechanism in the Heme-Dependent Chlorite Dismutase

Jeffrey A. Mayfield, Béatrice Blanc, Kenton R. Rodgers, Gudrun S. Lukat-Rodgers and Jennifer L. DuBois

Biochemistry, 2013, 52, 6982
DOI: 10.1021/bi4005599

Unexpected photosensitivity of the well-characterized heme enzyme chlorite dismutase

Durga Mahor, Julia Püschmann, Diederik R. Adema, Marc J. F. Strampraad and Peter-Leon Hagedoorn

J Biol Inorg Chem, 2020, 25, 1129
DOI: 10.1007/s00775-020-01826-8

Deciphering the role of the distal pocket in Staphylococcus aureus coproheme decarboxylase

Olivia R. Stiller, Bennett R. Streit, Garrett Honzay, Jennifer L. DuBois, Kenton R. Rodgers and Gudrun S. Lukat-Rodgers

Journal of Inorganic Biochemistry, 2025, 269, 112896
DOI: 10.1016/j.jinorgbio.2025.112896

From chlorite dismutase towards HemQ–the role of the proximal H-bonding network in haeme binding

Stefan Hofbauer, Barry D. Howes, Nicola Flego, Katharina F. Pirker, Irene Schaffner, Georg Mlynek, Kristina Djinović-Carugo, Paul G. Furtmüller, Giulietta Smulevich and Christian Obinger

Bioscience Reports, 2016, 36
DOI: 10.1042/BSR20150330

Distinguishing Active Site Characteristics of Chlorite Dismutases with Their Cyanide Complexes

Zachary Geeraerts, Arianna I. Celis, Jeffery A. Mayfield, Megan Lorenz, Kenton R. Rodgers, Jennifer L. DuBois and Gudrun S. Lukat-Rodgers

Biochemistry, 2018, 57, 1501
DOI: 10.1021/acs.biochem.7b01278

Unique Biradical Intermediate in the Mechanism of the Heme Enzyme Chlorite Dismutase

Julia Püschmann, Durga Mahor, Daniël C. de Geus, Marc J. F. Strampraad, Batoul Srour, Wilfred R. Hagen, Smilja Todorovic and Peter-Leon Hagedoorn

ACS Catal., 2021, 11, 14533
DOI: 10.1021/acscatal.1c03432

A traffic light enzyme: acetate binding reversibly switches chlorite dismutase from a red- to a green-colored heme protein

Durga Mahor, Julia Püschmann, Menno van den Haak, Pepijn J. Kooij, David L. J. van den Ouden, Marc J. F. Strampraad, Batoul Srour and Peter-Leon Hagedoorn

J Biol Inorg Chem, 2020, 25, 609
DOI: 10.1007/s00775-020-01784-1

Substrate, product, and cofactor: The extraordinarily flexible relationship between the CDE superfamily and heme

Arianna I. Celis and Jennifer L. DuBois

Archives of Biochemistry and Biophysics, 2015, 574, 3
DOI: 10.1016/j.abb.2015.03.004

Chlorite dismutases – a heme enzyme family for use in bioremediation and generation of molecular oxygen

Stefan Hofbauer, Irene Schaffner, Paul G. Furtmüller and Christian Obinger

Biotechnology Journal, 2014, 9, 461
DOI: 10.1002/biot.201300210

Tyr 118-Mediated Electron Transfer is Key to the Chlorite Decomposition in Heme-Dependent Chlorite Dismutase

Vandana Kardam and Kshatresh Dutta Dubey

Inorg. Chem., 2023, 62, 18322
DOI: 10.1021/acs.inorgchem.3c03334

Basidiomycete DyPs: Genomic diversity, structural–functional aspects, reaction mechanism and environmental significance

Dolores Linde, Francisco J. Ruiz-Dueñas, Elena Fernández-Fueyo, Victor Guallar, Kenneth E. Hammel, Rebecca Pogni and Angel T. Martínez

Archives of Biochemistry and Biophysics, 2015, 574, 66
DOI: 10.1016/j.abb.2015.01.018

Understanding molecular enzymology of porphyrin-binding α + β barrel proteins - One fold, multiple functions

Stefan Hofbauer, Vera Pfanzagl, Hanna Michlits, Daniel Schmidt, Christian Obinger and Paul G. Furtmüller

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2021, 1869, 140536
DOI: 10.1016/j.bbapap.2020.140536

Roles of High-Valent Hemes and pH Dependence in Halite Decomposition Catalyzed by Chlorite Dismutase fromDechloromonas aromatica

Zachary Geeraerts, Olivia R. Stiller, Gudrun S. Lukat-Rodgers and Kenton R. Rodgers

ACS Catal., 2022, 12, 8641
DOI: 10.1021/acscatal.2c01428

Transiently Produced Hypochlorite Is Responsible for the Irreversible Inhibition of Chlorite Dismutase

Stefan Hofbauer, Clemens Gruber, Katharina F. Pirker, Axel Sündermann, Irene Schaffner, Christa Jakopitsch, Chris Oostenbrink, Paul G. Furtmüller and Christian Obinger

Biochemistry, 2014, 53, 3145
DOI: 10.1021/bi500401k

Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa

Dimitrios V. Nokas, Eleni K. Panagiotopoulou, Antonios I. Kapogiannatos, Georgios E. Premetis, Nikolaos E. Labrou, Eleni K. Efthimiadou, Anastassios C. Papageorgiou and Evangelia G. Chronopoulou

The FEBS Journal, 2025, 292, 5398
DOI: 10.1111/febs.70151

Manipulating Conserved Heme Cavity Residues of Chlorite Dismutase: Effect on Structure, Redox Chemistry, and Reactivity

Stefan Hofbauer, Kira Gysel, Marzia Bellei, Andreas Hagmüller, Irene Schaffner, Georg Mlynek, Julius Kostan, Katharina F. Pirker, Holger Daims, Paul G. Furtmüller, Gianantonio Battistuzzi, Kristina Djinović-Carugo and Christian Obinger

Biochemistry, 2014, 53, 77
DOI: 10.1021/bi401042z

Mechanism of chlorite degradation to chloride and dioxygen by the enzyme chlorite dismutase

Irene Schaffner, Stefan Hofbauer, Michael Krutzler, Katharina F. Pirker, Paul G. Furtmüller and Christian Obinger

Archives of Biochemistry and Biophysics, 2015, 574, 18
DOI: 10.1016/j.abb.2015.02.031