Metal-free C(sp3)–H bond activation: first synthesis of diaryl-pyridinium-azaarene-butenolate zwitterionic salts on chalcones

Atul Kumar, Lalit Prakash Gupta and Mukesh Kumar

RSC Adv., 2013, 3, 18771
DOI: 10.1039/c3ra42761g

A facile and efficient one-pot synthesis of polysubstituted benzenes in guanidinium ionic liquids

Xin Xin, Yan Wang, Wu Xu, Yingjie Lin, Haifeng Duan and Dewen Dong

Green Chem., 2010, 12, 893
DOI: 10.1039/b921390b

A [3 + 2]–[4 + 2]–[3 + 2] cycloaddition sequence of isoquinolinium ylide

Ruzhang Liu, Rong-Guo Shi, Jing Sun and Chao-Guo Yan

Org. Chem. Front., 2017, 4, 354
DOI: 10.1039/C6QO00615A

Convenient construction of dibenzo[b,d]furanes and 2,6-diaryl-4-(2-hydroxyphenyl)pyridines via domino reaction of pyridinium ylides with 2-aryl-3-nitrochromenes

Jing Sun, Wang Jiang and Chao-Guo Yan

Org. Chem. Front., 2019, 6, 1428
DOI: 10.1039/C9QO00079H

Palladium catalyzed one-pot synthesis of 2-(pyridin-4-yl) quinolines via a multicomponent unprecedented reaction of pyridine-4-carbaldehyde, 2-iodoaniline and triethylamine

Atiur Ahmed, Shubhendu Dhara, Raju Singha, Yasin Nuree, Pompy Sarkar and Jayanta K. Ray

RSC Adv., 2014, 4, 53137
DOI: 10.1039/C4RA08624D

Synthesis of spiro[isoquinolinone-4,2′-oxiranes] and isoindolinones via a multicomponent reaction of 2-acetyl-oxirane-2-carboxamides, arylaldehydes and malononitrile

Bing Liu, Enxiang Wei, Shaoxia Lin, Baozhong Zhao and Fushun Liang

Chem. Commun., 2014, 50, 6995
DOI: 10.1039/c4cc02141j

Primary 1,2-diamine catalysis III: an unexpected domino reaction for the synthesis of multisubstituted cyclohexa-1,3-dienamines

Junfeng Wang, Qin Li, Chao Qi, Yi Liu, Zemei Ge and Runtao Li

Org. Biomol. Chem., 2010, 8, 4240
DOI: 10.1039/c0ob00089b

Diastereoselective synthesis of spiro[benzo[d]pyrrolo[2,1-b]thiazole-3,3′-indolines] via cycloaddition reaction of N-phenacylbenzothiazolium bromides and 3-methyleneoxindoles

Guo-Liang Shen, Jing Sun and Chao-Guo Yan

Org. Biomol. Chem., 2015, 13, 10929
DOI: 10.1039/C5OB01374G

Diastereoselective synthesis of spirocyclic isoxazolo[5,4-c]pyrrolo[2,1-a]isoquinolines via cascade double [3 + 2]cycloadditions

Dan Liu, Jing Sun, Yu Zhang and Chao-Guo Yan

Org. Biomol. Chem., 2019, 17, 8008
DOI: 10.1039/C9OB01474H

Diastereoselective synthesis of benzo[d]chromeno[3′,4′:3,4]pyrrolo[2,1-b]thiazoles via cycloaddition reaction of benzothiazolium salts with 3-nitrochromenes

Wang Jiang, Jing Sun and Chao-Guo Yan

RSC Adv., 2017, 7, 42387
DOI: 10.1039/C7RA06548E

New multicomponent cyclization: domino synthesis of pentasubstituted pyridines under solvent-free conditions

Bo Jiang, Xiang Wang, Feng Shi, Shu-Jiang Tu and Guigen Li

Org. Biomol. Chem., 2011, 9, 4025
DOI: 10.1039/c0ob01258k

Efficient approach to 2-hydroxy-2,3-dihydrofuran derivatives and its application for the synthesis of novel 4-(1H-pyrazol-4-yl)pyridazines

Jun-Rui Ma, Wen-Ming Shu, Kai-Lu Zheng, Fan Ni, Guo-Dong Yin and An-Xin Wu

Org. Biomol. Chem., 2015, 13, 4976
DOI: 10.1039/C5OB00163C

Organocatalyzed straightforward synthesis of highly fluorescent 3,5-disubstituted 2,6-dicyanoanilines via domino annulation of α-enolicdithioesters with malononitrile

B. Janaki Ramulu, Tanmoy Chanda, Sushobhan Chowdhury, Ganesh C. Nandi and Maya Shankar Singh

RSC Adv., 2013, 3, 5345
DOI: 10.1039/c3ra40450a

Selective synthesis of spirooxindoles via a two-step reaction of N-phenacylpyridinium bromide, 1,3-indanedione and N-alkylisations

Jing Sun, Yu Zhang, Rong-Guo Shi and Chao-Guo Yan

Org. Biomol. Chem., 2019, 17, 3978
DOI: 10.1039/C9OB00166B

Facile synthesis of spiro[indoline-3,3′-pyrrolo[1,2-a]quinolines] and spiro[indoline-3,1′-pyrrolo[2,1-a]isoquinolines] via 1,3-dipolar cycloaddition reactions of heteroaromatic ammonium salts with 3-phenacylideneoxindoles

Lei Wu, Jing Sun and Chao-Guo Yan

Org. Biomol. Chem., 2012, 10, 9452
DOI: 10.1039/c2ob26849c

Efficient synthesis of tetra- and penta-substituted benzenes via a domino annulation reaction of a pyridinium ylide and chalcone o-enolate

Feng-Shun Xu, Chen Yan, Jing Sun and Chao-Guo Yan

New J. Chem., 2021, 45, 19666
DOI: 10.1039/D1NJ03772B

I2-promoted formal [3 + 1 + 1 + 1] cyclization to construct 5-cyano-1H-pyrazolo[3,4-b]pyridine using malononitrile as a C1 synthon

Zhi-Cheng Yu, Xi Shen, You Zhou, Xiang-Long Chen, Li-Sheng Wang, Yan-Dong Wu, Hao-Ke Zhang, Kai-Lu Zheng and An-Xin Wu

Org. Chem. Front., 2023, 10, 5958
DOI: 10.1039/D3QO01299A

A convenient three-component reaction leading to the synthesis of polysubstituted cyclohexene derivatives

Xiao-Yang Guan and Min Shi

Org. Biomol. Chem., 2008, 6, 3616
DOI: 10.1039/b810299f

Catalyst-free stereoselective cyclopropanation of electron deficient alkenes with ethyl diazoacetate

Ram Awatar Maurya, Jeevak Sopanrao Kapure, Praveen Reddy Adiyala, Srikanth P. S., D. Chandrasekhar and Ahmed Kamal

RSC Adv., 2013, 3, 15600
DOI: 10.1039/c3ra42374c

Formation of zwitterionic salts via three-component reaction of benzimidazolium bromides, aromatic aldehydes and 1,3-indanedione

Gong Jin, Jing Sun and Chao-Guo Yan

RSC Adv., 2016, 6, 84379
DOI: 10.1039/C6RA16838H

Zinc titanate nanopowder: an advanced nanotechnology based recyclable heterogeneous catalyst for the one-pot selective synthesis of self-aggregated low-molecular mass acceptor–donor–acceptor–acceptor systems and acceptor–donor–acceptor triads

Paramita Das, Ray J. Butcher and Chhanda Mukhopadhyay

Green Chem., 2012, 14, 1376
DOI: 10.1039/c2gc16641k

Multicomponent reaction of chalcones, malononitrile and DMF leading to γ-ketoamides

Enxiang Wei, Bing Liu, Shaoxia Lin and Fushun Liang

Org. Biomol. Chem., 2014, 12, 6389
DOI: 10.1039/C4OB00971A

Construction of dispirocyclohexyl-3,3′-bisoxindole and dispirocyclopentyl-3,3′-bisoxindole via domino cycloaddition reactions of N-benzylbenzimidazolium salts with 2-(2-oxoindolin-3-ylidene)acetates

Guo-Liang Shen, Jing Sun and Chao-Guo Yan

RSC Adv., 2015, 5, 4475
DOI: 10.1039/C4RA13760D

Molecular Diversity of the Three‐Component Reactions of N‐Benzylbenzimidazolium Salts, Aromatic Aldehydes, and Active Methylene Compounds

Li Hui, Yu‐Xiu Jin, Jin‐Xiu Wang and Chao‐Guo Yan

Eur J Org Chem, 2011, 2011, 7194
DOI: 10.1002/ejoc.201101199

Application of Functionalized N,S‐Ketene Acetals–Microwave‐Assisted Three‐Component Domino Reaction for Rapid Direct Access to Imidazo[1,2‐a]pyridines

Ming Li, Tengfei Li, Kelong Zhao, Mingda Wang and Lirong Wen

Chin. J. Chem., 2013, 31, 1033
DOI: 10.1002/cjoc.201300252

Organobase-catalyzed three-component reactions for the synthesis of 4H-2-aminopyrans, condensed pyrans and polysubstituted benzenes

Moustafa Sherief Moustafa, Saleh Mohammed Al-Mousawi, Maghraby Ali Selim, Ahmed Mohamed Mosallam and Mohamed Hilmy Elnagdi

Beilstein J. Org. Chem., 2014, 10, 141
DOI: 10.3762/bjoc.10.11

Recent Advances in Ester Synthesis by Multi-Component Reactions (MCRs): A Review

Dhaval B. Patel, Jagruti A. Parmar, Siddharth S. Patel, Unnati J. Naik and Hitesh D. Patel

COC, 2021, 25, 539
DOI: 10.2174/1385272825666210111111805

Construction of Oxa‐Bridged Tetracyclic Frameworks through a Prins Bicyclic Annulation

Preethi N. Nair, Vangala Swathi, Ghaytadak Nishigandha, Balasubramanian Sridhar, Jithender G Reddy and Basi V. Subba Reddy

Eur J Org Chem, 2019, 2019, 3567
DOI: 10.1002/ejoc.201801788

Synthesis of New Class of Alkyl Azarene Pyridinium Zwitterions via Iodine Mediated sp3 C–H Bond Activation

Atul Kumar, Garima Gupta and Suman Srivastava

Org. Lett., 2011, 13, 6366
DOI: 10.1021/ol202654j

Pyridinium Ylide-Assisted One-Pot Two-Step Tandem Synthesis of Polysubstituted Cyclopropanes

Qi-Fang Wang, Xiao-Kai Song, Jiao Chen and Chao-Guo Yan

J. Comb. Chem., 2009, 11, 1007
DOI: 10.1021/cc900005v

A Domino Reaction of Pyridinium Salts: Efficient Synthesis of 4,5‐Disubstituted 1,2,3‐(NH)‐Triazoles

Guang‐Long Wu and Qin‐Pei Wu

ChemistrySelect, 2018, 3, 5212
DOI: 10.1002/slct.201800669

Application of ortho-chloro-β-aroylthioamides in synthesis(II): an efficient one-pot, three-component synthesis of tricyclic thiochromeno[2,3-b]pyridine derivatives

Li-Rong Wen, Chen Ji, Ming Li and Huai-Yuan Xie

Tetrahedron, 2009, 65, 1287
DOI: 10.1016/j.tet.2008.12.057

Triethylamine‐Catalyzed Domino Reactions of 1,3‐Thiazolidinedione: A Facile Access to Functionalized Dihydrothiophenes

Jing Sun, Er‐Yan Xia, Li‐Li Zhang and Chao‐Guo Yan

Eur J Org Chem, 2009, 2009, 5247
DOI: 10.1002/ejoc.200900845

One-pot two-step tandem reactions for selective synthesis of pyrrolo[2,1-a]isoquinolines and dihydro-, tetrahydro-derivatives

Ying Han, Hong Hou, Qin Fu and Chao-Guo Yan

Tetrahedron, 2011, 67, 2313
DOI: 10.1016/j.tet.2011.01.046

Synthesis of cyclopropane-1,1,2,2-tetracarboxylic acid derivatives from aldehydes and CH-acids in the K2CO3/Bun 4NPF6/toluene heterogeneous system

G. V. Kryshtal, G. M. Zhdankina and S. G. Zlotin

Russ Chem Bull, 2011, 60, 2286
DOI: 10.1007/s11172-011-0349-7

Synthesis of Dihydrothiophenes or Spirocyclic Compounds by Domino Reactions of 1,3-Thiazolidinedione

Jing Sun, Li-Li Zhang, Er-Yan Xia and Chao-Guo Yan

J. Org. Chem., 2009, 74, 3398
DOI: 10.1021/jo900215a

Synthesis of ammonium S–S bond linked dipyridinedionates via four-component reactions of cyanoacetamide, aldehyde, amine and 1,3-thiazolidinedione

Jing Sun, Er-Yan Xia, Qun Wu and Chao-Guo Yan

Tetrahedron, 2010, 66, 7794
DOI: 10.1016/j.tet.2010.07.051

Diastereoselective Synthesis of trans-2,3-Dihydrofurans with Pyridinium Ylide Assisted Tandem Reaction

Qi-Fang Wang, Hong Hou, Li Hui and Chao-Guo Yan

J. Org. Chem., 2009, 74, 7403
DOI: 10.1021/jo901379h

One-Step Synthesis of Pyrido[1,2-a]benzimidazole Derivatives by a Novel Multicomponent Reaction of Chloroacetonitrile, Malononitrile, Aromatic Aldehyde, and Pyridine

Chao Guo Yan, Qi Fang Wang, Xiao Kai Song and Jing Sun

J. Org. Chem., 2009, 74, 710
DOI: 10.1021/jo802166t

Imidazole‐Mediated Cascade [2 + 2 + 2] Annulation Reactions: A Highly Diastereoselective Synthetic Protocol for the Construction of Multiply Substituted Cyclohexanes

Xu‐Guang Liu and Min Shi

Eur J Org Chem, 2008, 2008, 6168
DOI: 10.1002/ejoc.200800853

Synthesis of 6a,6b,13,13a-tetrahydro-6H-5-oxa-12a-azadibenzo[a,g]fluorene derivatives via cycloaddition reactions of isoquinolinium salts with 3-nitrochromenes

Jun Fang and Chao-Guo Yan

Mol Divers, 2014, 18, 91
DOI: 10.1007/s11030-013-9489-z

Formation of diverse polycyclic spirooxindoles via three-component reaction of isoquinolinium salts, isatins and malononitrile

Jing Sun, Guo-liang Shen, Ying Huang and Chao-Guo Yan

Sci Rep, 2017, 7
DOI: 10.1038/srep41024

DBU- and DABCO-Promoted Selective Access to 2,5-Diarylnitrobenzoates and Cyclohexenones via One-Pot Reactions

Shikha Singh Rathor, Debashis Majee and Sampak Samanta

Synlett, 2022, 33, 1052
DOI: 10.1055/a-1817-0882

Design and synthesis of novel pyridinium nitrate-bearing substituted anilines via one-pot tandem reactions

Yang Huijuan, Ren Yujie, Xu Wenqian and Li Ren

Journal of Chemical Research, 2017, 41, 384
DOI: 10.3184/174751917X14967701766950

A convenient strategy for the annulation of aryl scaffold to A/B-ring steroids under microwave irradiation

Madan G. Barthakur, Abdul Hasib, Junali Gogoi and Romesh C. Boruah

Steroids, 2010, 75, 445
DOI: 10.1016/j.steroids.2010.02.009

Facile three-component synthesis and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine derivatives

Ye-Feng Fan, Wen-Wen Zhang, Xu-Sheng Shao, Zhi-Ping Xu, Xiao-Yong Xu and Zhong Li

Chinese Chemical Letters, 2015, 26, 1
DOI: 10.1016/j.cclet.2014.10.019

Diastereoselective Desymmetrization of Prochiral Cyclopentenediones via Cycloaddition Reaction with N-Phenacylbenzothiazolium Bromides

Subas Chandra Sahoo, Mayank Joshi and Subhas Chandra Pan

J. Org. Chem., 2017, 82, 12763
DOI: 10.1021/acs.joc.7b01964

Formation of N,S‐Containing Polycycles via Base Promoted Dimerization of N‐Phenacyl and N‐Benzylbenzothiazolium Bromides

Bang‐Dong Ding, Jing Sun, Wang Jiang, Gong Jin and Chao‐Guo Yan

ChemistrySelect, 2020, 5, 1092
DOI: 10.1002/slct.201904941

The unprecedented C-alkylation and tandem C-/O-alkylation of phenanthrolinium salts with cyclic 1,3-dicarbonyl compounds

Hui Li and Chao-Guo Yan

Tetrahedron, 2011, 67, 2863
DOI: 10.1016/j.tet.2011.02.063

Convenient Synthesis of Functionalized 3,4,10,11‐tetrahydroindolo[1,2‐a]Quinoxalines Via Three‐component Reaction of Dimedone, 3‐nitrochromenes and Ammonium Acetate

Jun Fang and Chao‐Guo Yan

Journal of Heterocyclic Chem, 2016, 53, 800
DOI: 10.1002/jhet.2345

Molecular diversity of cycloaddition reactions of the functionalized pyridinium salts with 3-phenacylideneoxindoles

Qin Fu and Chao-Guo Yan

Tetrahedron, 2013, 69, 5841
DOI: 10.1016/j.tet.2013.05.034

Synthesis of Zwitterionic Salts of Pyridinium-Meldrum Acid and Barbiturate through Unique Four-component Reactions

Qi-Fang Wang, Li Hui, Hong Hou and Chao-Guo Yan

J. Comb. Chem., 2010, 12, 260
DOI: 10.1021/cc900161z

Recyclable Hypervalent-Iodine-Mediated Dehydrogenative Cyclopropanation under Metal-Free Conditions

Ya-Nan Duan, Zhao Zhang and Chi Zhang

Org. Lett., 2016, 18, 6176
DOI: 10.1021/acs.orglett.6b03209

Stepwise cycloaddition reaction of N-phenacylbenzothiazolium bromides and nitroalkenes for tetrahydro-, dihydro- and benzo[d]pyrrolo[2,1-b]thiazoles

Gong Jin, Jing Sun, Ren-Yin Yang and Chao-Guo Yan

Sci Rep, 2017, 7
DOI: 10.1038/srep46470

Synthesis of complex dispirocyclopentanebisoxindoles via cycloaddition reactions of 4-dimethylamino-1-alkoxycarbonylmethylpyridinium bromides with 2-oxoindolin-3-ylidene derivatives

Li-Juan Lu, Qin Fu, Jing Sun and Chao-Guo Yan

Tetrahedron, 2014, 70, 2537
DOI: 10.1016/j.tet.2014.02.050

The Effect of Fluorinated Benzothiadiazole-dicyanovinyl Acceptors on the Dielectric Constants of Organic Photovoltaic Materials

Neil Mallo, Shaun McAnally, Hui Jin, Mohammad Babazadeh, Lachlan Packman, Ronan Chu, Paul L. Burn, Ian R. Gentle and Paul E. Shaw

ACS Appl. Energy Mater., 2024, 7, 3393
DOI: 10.1021/acsaem.4c00140

Molecular Diversity of Three‐Component Reactions of N‐Benzylbenzimidazolium Salts, Isatin, and Malononitrile or Ethyl Cyanoacetate

Li Hui, Hong‐Yan Li and Chao‐Guo Yan

Eur J Org Chem, 2012, 2012, 3157
DOI: 10.1002/ejoc.201200269

Convenient Synthesis of Spiro[benzo[d]pyrrolo[2,1‐b]thiazole‐3,2′‐indenes] Derivatives via Three‐Component Reaction

Guoliang Shen, Jing Sun and Chaoguo Yan

Chin. J. Chem., 2016, 34, 412
DOI: 10.1002/cjoc.201500896

Synthesis of zwitterionic salts via three-component reactions of pyridacylpyridinum iodide, aromatic aldehydes, and Meldrum acid or N,N-dimethylbarbituric acid

Ying Han, Jiao Chen, Li Hui and Chao-Guo Yan

Tetrahedron, 2010, 66, 7743
DOI: 10.1016/j.tet.2010.07.073

Efficient Synthesis of Complex Oxazatricycles via Three‐Component Reaction of Isoquinolinium Salts, Acetone and Cyclic Diketones

Li‐Juan Liu and Chao‐Guo Yan

Journal of Heterocyclic Chem, 2015, 52, 1513
DOI: 10.1002/jhet.2201

Convenient synthesis of polyfunctional dihydrothiophenes with tandem reaction of 1,3-thiazolidinedione, aldehyde, arylamine and ethyl cyanoacetate

Jing Sun, Er-Yan Xia, Rong Yao and Chao-Guo Yan

Mol Divers, 2011, 15, 115
DOI: 10.1007/s11030-010-9278-x

Divergent Synthesis of Steroid Analogs from Steroidal β-Formylenamides, Conjugated Enones and β-Formylvinyl Halides

Romesh C. Boruah and Geetmani S. Nongthombam

HETEROCYCLES, 2019, 98, 19
DOI: 10.3987/REV-18-898

Molecular Diversity of 1,3‐Dipolar Cycloaddition of Quinolinium Ylides with Isatylidene Malononitriles

Jing Sun, Yu Zhang, Guo‐Liang Shen and Chao‐Guo Yan

ChemistrySelect, 2017, 2, 10835
DOI: 10.1002/slct.201702161

ChemInform Abstract: One‐Step Synthesis of Polysubstituted Benzene Derivatives by Multicomponent Cyclization of α‐Bromoacetate, Malononitrile and Aromatic Aldehydes.

Chao Guo Yan, Xiao Kai Song, Qi Fang Wang, Jing Sun, Ulrich Siemeling and Clemens Bruhn

ChemInform, 2008, 39
DOI: 10.1002/chin.200829092

Potassium carbonate catalyzed one pot four-component synthesis of rhodanine derivatives

Sarangthem Joychandra Singh and S.M.S. Chauhan

Tetrahedron Letters, 2013, 54, 2484
DOI: 10.1016/j.tetlet.2013.03.004

Platinum(IV)‐Catalyzed Synthesis of Unsymmetrical Polysubstituted Benzenes via Intramolecular Cycloaromatization Reaction

Shuyan Zheng, Jinghua Zhang and Zhengwu Shen

Adv Synth Catal, 2015, 357, 2803
DOI: 10.1002/adsc.201500573

Base-Catalyzed Efficient Tandem [3 + 3] and [3 + 2 + 1] Annulation-Aerobic Oxidative Benzannulations

Aboubacar Diallo, Yu-Long Zhao, He Wang, Sha-Sha Li, Chuan-Qing Ren and Qun Liu

Org. Lett., 2012, 14, 5776
DOI: 10.1021/ol302829f

Synthesis of Ammonium 3,5-Dicyano-4-aryl-2,6-pyridinedionates with One-Pot Reaction of Aromatic Aldehydes, Amines, and Cyanoacetamide

Ying Han, Er-Yan Xia, Qun Wu, Jing Sun and Chao-Guo Yan

Synthetic Communications, 2013, 43, 1413
DOI: 10.1080/00397911.2011.636497

A facile synthesis of tricyclic skeleton of alkaloid 261C by double [3+2] cycloaddition of pyridinium ylide

Ruzhang Liu, Xianya Wang, Jing Sun and Chao-Guo Yan

Tetrahedron Letters, 2015, 56, 6711
DOI: 10.1016/j.tetlet.2015.10.049

A novel four-component reaction involving ring-opening/recyclization of 1,3-thiazolidinedione

Jing Sun, ErYan Xia, LiLi Zhang and ChaoGuo Yan

Sci. China Chem., 2010, 53, 863
DOI: 10.1007/s11426-010-0123-y

Facile synthesis of functionalized spiro[indoline-3,2'-oxiran]-2-ones by Darzens reaction

Qin Fu and Chao-Guo Yan

Beilstein J. Org. Chem., 2013, 9, 918
DOI: 10.3762/bjoc.9.105