Issue 16, 2024

Biomaterials as a new option for treating sensorineural hearing loss

Abstract

Sensorineural hearing loss (SNHL) usually involves damage to complex auditory pathways such as inner ear cells and auditory nerves. The highly intricate and nuanced characteristics of these cells render their repair and regeneration extremely challenging, making it difficult to restore hearing to normal levels once it has been compromised. The effectiveness of traditional drugs is so minimal that they provide little help with the treatment. Fortunately, extensive experiments have demonstrated that combining biomaterials with conventional techniques significantly enhances drug effectiveness. This article reviews the research progress of biomaterials in protecting hair cells and the auditory nerve, repairing genes related to hearing, and developing artificial cochlear materials. By organizing the knowledge presented in this article, perhaps new insights can be provided for the clinical management of SNHL.

Graphical abstract: Biomaterials as a new option for treating sensorineural hearing loss

Article information

Article type
Review Article
Submitted
16 apr 2024
Accepted
30 iyn 2024
First published
05 iyl 2024

Biomater. Sci., 2024,12, 4006-4023

Biomaterials as a new option for treating sensorineural hearing loss

L. Wang, R. Zhang, L. Jiang, S. Gao, J. Wu and Y. Jiao, Biomater. Sci., 2024, 12, 4006 DOI: 10.1039/D4BM00518J

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