Issue 18, 2022

A carboxylatopillar[5]arene-based pH-triggering supramolecular photosensitizer for enhanced photodynamic antibacterial efficacy

Abstract

A pH-triggering supramolecular antibacterial photosensitizer was constructed by host–guest interaction between a water-soluble porphyrin photosensitizer and carboxylatopillar[5]arene (P[5]). The formation of the supramolecular complex not only improves the biocompatibility of the photosensitizer, but also enhances antibacterial efficacy by pH-triggering dissociation under the low pH bacterial microenvironment.

Graphical abstract: A carboxylatopillar[5]arene-based pH-triggering supramolecular photosensitizer for enhanced photodynamic antibacterial efficacy

Supplementary files

Article information

Article type
Communication
Submitted
29 okt 2021
Accepted
19 yan 2022
First published
21 yan 2022

Chem. Commun., 2022,58, 2991-2994

A carboxylatopillar[5]arene-based pH-triggering supramolecular photosensitizer for enhanced photodynamic antibacterial efficacy

T. Yue, L. Xia, J. Tian, B. Huang, C. Chen, H. Cao and W. Zhang, Chem. Commun., 2022, 58, 2991 DOI: 10.1039/D1CC06116J

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