Issue 21, 2021

Advances in regioselective functionalization of 9-phenanthrenols

Abstract

9-Hydroxyphenanthrene is an important derivative of phenanthrene, which has been used in the fields of organic synthesis, material chemistry, and pharmaceutical chemistry. Phenanthrene is the second most abundant polycyclic aromatic hydrocarbon in coal tar and can be used for large-scale preparation of 9-hydroxyphenanthrene. Due to the lack of strategies, regioselective functionalization of 9-hydroxyphenanthrene is very challenging, especially on C1–C8 sites. In order to promote the application of phenanthrene, this review summarizes the methods for regioselective functionalization of 9-hydroxyphenanthrene and its ether derivatives on different sites. The corresponding reaction mechanisms are introduced in detail. We also provide the reaction characteristics of 9-hydroxyphenanthrene, and we offer our views on the challenges and the future research direction of 9-hydroxyphenanthrene.

Graphical abstract: Advances in regioselective functionalization of 9-phenanthrenols

Article information

Article type
Review Article
Submitted
26 may 2021
Accepted
02 iyl 2021
First published
06 iyl 2021

Org. Chem. Front., 2021,8, 6125-6137

Advances in regioselective functionalization of 9-phenanthrenols

D. Wang, J. Qi and Q. Wang, Org. Chem. Front., 2021, 8, 6125 DOI: 10.1039/D1QO00811K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements