Issue 44, 2020

Diverse synthesis of pyrano[3,2-c]coumarins: a brief update

Abstract

Functionalized pyranocoumarins are an important class of oxygen-containing heterocyclic compounds. Fused coumarin systems, in particular pyranocoumarins, are abundant in nature and constitute building blocks for many natural products found across the plant kingdom. Pyranocoumarin derivatives have been found to possess antifungal, insecticidal, anticancer, anti-HIV, anti-inflammatory, antioxidant, and antibacterial activities. Synthesis of this moiety from easily available chemicals is desirable due to its tremendous use in various branches of chemistry. Owing to the broad spectrum of biological properties and natural occurrence, pyrano[3,2-c]coumarins have become attractive synthetic targets from the point of view of medicinal chemistry. This short review discusses the synthesis of this scaffold using different strategies including mechanistic illustrations.

Graphical abstract: Diverse synthesis of pyrano[3,2-c]coumarins: a brief update

Article information

Article type
Perspective
Submitted
30 iyl 2020
Accepted
23 sen 2020
First published
24 sen 2020

New J. Chem., 2020,44, 18980-18993

Diverse synthesis of pyrano[3,2-c]coumarins: a brief update

A. Mukherjee, S. Mahato, G. V. Zyryanov, A. Majee and S. Santra, New J. Chem., 2020, 44, 18980 DOI: 10.1039/D0NJ03846F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements