Issue 19, 2018

Spatially resolved coding of λ-orthogonal hydrogels by laser lithography

Abstract

A λ-orthogonal reaction system is introduced, where visible light induced radical thiol–ene and UV light induced NITEC (Nitrile-Imine mediated Tetrazole–Ene Conjugation) ligations are consecutively employed to fabricate and functionalize PEG-based hydrogels. The fluorescent pyrazoline cycloadducts from the NITEC reaction are exploited to visualize the written structures within the hydrogels as well as to attach RGD containing functional groups to promote spatially resolved cell attachment on the hydrogel surface.

Graphical abstract: Spatially resolved coding of λ-orthogonal hydrogels by laser lithography

Supplementary files

Article information

Article type
Communication
Submitted
15 dek 2017
Accepted
07 fev 2018
First published
19 fev 2018

Chem. Commun., 2018,54, 2436-2439

Spatially resolved coding of λ-orthogonal hydrogels by laser lithography

R. R. Batchelor, E. Blasco, K. N. R. Wuest, H. Lu, M. Wegener, C. Barner-Kowollik and M. H. Stenzel, Chem. Commun., 2018, 54, 2436 DOI: 10.1039/C7CC09619D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements