Issue 12, 2018

Oxidative radical divergent Si-incorporation: facile access to Si-containing heterocycles

Abstract

A copper-catalyzed oxidative radical strategy to avoid the use of the highly expensive noble metal/ligand catalytic systems is described, which allows selective activation of dual chemical bonds around the Si-atom center relying on the nature of alkylsilanes. While for tertiary silanes selective functionalization of Si–H/silyl C(sp3)–H bonds in intermolecular oxidative annulation cascades with N-(2-(ethynyl)aryl)acrylamides toward silino[3,4-c]quinolin-5(3H)-ones, when using secondary silanes and HSi(TMS)3, dual Si–H bonds or Si–H/Si–Si bonds are selectively cleaved leading to 4H-silolo[3,4-c]quinolin-4-ones.

Graphical abstract: Oxidative radical divergent Si-incorporation: facile access to Si-containing heterocycles

Supplementary files

Article information

Article type
Communication
Submitted
21 noy 2017
Accepted
05 yan 2018
First published
05 yan 2018

Chem. Commun., 2018,54, 1441-1444

Oxidative radical divergent Si-incorporation: facile access to Si-containing heterocycles

Y. Yang, R. Song, Y. Li, X. Ouyang, J. Li and D. He, Chem. Commun., 2018, 54, 1441 DOI: 10.1039/C7CC08964C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements