Issue 5, 2010

Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

Abstract

Direct selective palladium catalyzed C–H functionalization has become a highly attractive strategy in organic synthesis and represents a highly desirable goal. Compared with cross-coupling reactions of C–H bonds with aryl or alkyl halides/pseudohalides, the strategy of cross-coupling reactions of C–H bonds with organometallic reagents is of great significance and obvious advantages. This feature article provides a comprehensive summary of recent advances and an intensive analysis on Pd-catalyzed C–H activation and oxidative coupling with various organometallic reagents.

Graphical abstract: Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

Article information

Article type
Feature Article
Submitted
29 apr 2009
Accepted
25 noy 2009
First published
05 yan 2010

Chem. Commun., 2010,46, 677-685

Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

C. Sun, B. Li and Z. Shi, Chem. Commun., 2010, 46, 677 DOI: 10.1039/B908581E

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