Issue 44, 2023

Metal–organic gels: recent advances in their classification, characterization, and application in the pharmaceutical field

Abstract

Metal–organic gels (MOGs) are a type of functional soft substance with a three-dimensional (3D) network structure and solid-like rheological behavior, which are constructed by metal ions and bridging ligands formed under the driving force of coordination interactions or other non-covalent interactions. As the homologous substances of metal–organic frameworks (MOFs) and gels, they exhibit the potential advantages of high porosity, flexible structure, and adjustable mechanical properties, causing them to attract extensive research interest in the pharmaceutical field. For instance, MOGs are often used as excellent vehicles for intelligent drug delivery and programmable drug release to improve the clinical curative effect with reduced side effects. Also, MOGs are often applied as advanced biomedical materials for the repair and treatment of pathological tissue and sensitive detection of drugs or other molecules. However, despite the vigorous research on MOGs in recent years, there is no systematic summary of their applications in the pharmaceutical field to date. The present review systematically summarize the recent research progress on MOGs in the pharmaceutical field, including drug delivery systems, drug detection, pharmaceutical materials, and disease therapies. In addition, the formation principles and classification of MOGs are complemented and refined, and the techniques for the characterization of the structures/properties of MOGs are overviewed in this review.

Graphical abstract: Metal–organic gels: recent advances in their classification, characterization, and application in the pharmaceutical field

Article information

Article type
Review Article
Submitted
17 iyl 2023
Accepted
17 okt 2023
First published
20 okt 2023

J. Mater. Chem. B, 2023,11, 10566-10594

Metal–organic gels: recent advances in their classification, characterization, and application in the pharmaceutical field

W. Cao, Z. Lin, D. Zheng, J. Zhang, W. Heng, Y. Wei, Y. Gao and S. Qian, J. Mater. Chem. B, 2023, 11, 10566 DOI: 10.1039/D3TB01612A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements