Issue 6, 2023

Photocatalytic dehydrations for the Ritter reaction

Abstract

The Ritter reaction is a powerful method for the synthesis of amides; however, the photoinduced Ritter reaction of alcohols is rarely reported. We herein report a simple and additive-free photocatalytic dehydration method for the efficient direct conversion of benzyl alcohols to the corresponding amides using an organic photocatalyst 2,4,6-triphenylpyrylium salt. Experimental and computational mechanistic analyses show that a non-conventional generation process of a carbocation is involved in this photoinduced Ritter reaction.

Graphical abstract: Photocatalytic dehydrations for the Ritter reaction

Supplementary files

Article information

Article type
Research Article
Submitted
28 dek 2022
Accepted
09 fev 2023
First published
11 fev 2023

Org. Chem. Front., 2023,10, 1375-1379

Photocatalytic dehydrations for the Ritter reaction

L. Bao, B. Zhang, Z. Wang and X. Chen, Org. Chem. Front., 2023, 10, 1375 DOI: 10.1039/D2QO02046G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements