Issue 17, 2023

Platelet-derived extracellular vesicles for drug delivery

Abstract

Platelet-derived extracellular vesicles (PEVs) are a subset of EVs that are released from platelets, which are small nuclear cell fragments that play a critical role in hemostasis and thrombosis. PEVs have been shown to have important roles in a variety of physiological and pathological processes, including inflammation, angiogenesis, and cancer. Recently, researchers, including our group have utilized PEVs as drug delivery platforms as PEVs could target inflammatory sites both passively and actively. This review summarizes the biological function of PEVs, introduces recent applications of PEVs in targeted drug delivery, and provides an outlook for the further development of utilizing PEVs for drug delivery.

Graphical abstract: Platelet-derived extracellular vesicles for drug delivery

Article information

Article type
Review Article
Submitted
24 may 2023
Accepted
10 iyl 2023
First published
11 iyl 2023

Biomater. Sci., 2023,11, 5758-5768

Platelet-derived extracellular vesicles for drug delivery

C. Yao and C. Wang, Biomater. Sci., 2023, 11, 5758 DOI: 10.1039/D3BM00893B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements