Issue 32, 2022

An update on biomaterials as microneedle matrixes for biomedical applications

Abstract

Microneedles (MNs) have been developed for various applications such as drug delivery, cosmetics, diagnosis, and biosensing. To meet the requirements of MNs used in these areas, numerous materials have been used for the fabrication of MNs. However, MNs will be exposed to skin tissues after piercing the stratum corneum barrier. Thus, it is necessary to ensure that the matrix materials of MNs have the characteristics of low toxicity, good biocompatibility, biodegradability, and sufficient mechanical properties for clinical application. In this review, the matrix materials currently used for preparing MNs are summarized and reviewed in terms of these factors. In addition, MN products used on the market and their applications are summarized in the end. This work may provide some basic information to researchers in the selection of MN matrix materials and in developing new materials.

Graphical abstract: An update on biomaterials as microneedle matrixes for biomedical applications

Article information

Article type
Review Article
Submitted
26 apr 2022
Accepted
16 iyn 2022
First published
01 iyl 2022

J. Mater. Chem. B, 2022,10, 6059-6077

An update on biomaterials as microneedle matrixes for biomedical applications

X. P. Zhang, Y. T. He, W. X. Li, B. Z. Chen, C. Y. Zhang, Y. Cui and X. D. Guo, J. Mater. Chem. B, 2022, 10, 6059 DOI: 10.1039/D2TB00905F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements