Issue 37, 2022

Recent advances in biomedical applications of bacterial outer membrane vesicles

Abstract

Nanoscale and non-self-replicating outer membrane vesicles (OMVs) are naturally secreted by some bacteria with their structures and compositions similar to that of the outer membrane of parental bacteria. With some specific bacterial physiological characteristics, e.g., immunomodulations and intercellular communications, OMVs have been intensively studied and extensively used and engineered as vaccines, immunotherapeutic drugs, anti-bacterial agents, and drug delivery carriers. In this review, we describe the extraction, characterization, and functionalization of OMVs with emphasis on the latest progress and prospects in biomedical applications.

Graphical abstract: Recent advances in biomedical applications of bacterial outer membrane vesicles

Article information

Article type
Review Article
Submitted
28 mar 2022
Accepted
14 iyn 2022
First published
16 iyn 2022

J. Mater. Chem. B, 2022,10, 7384-7396

Recent advances in biomedical applications of bacterial outer membrane vesicles

H. Chen, M. Zhou, Y. Zeng, Z. Lv, P. Wang and L. Han, J. Mater. Chem. B, 2022, 10, 7384 DOI: 10.1039/D2TB00683A

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