Issue 42, 2022

Multi-analyte sensing strategies towards wearable and intelligent devices

Abstract

Continuous efforts to produce functional nanomaterials and flexible/stretchable devices have promoted cumbersome, laboratorial, detection processes toward wearable and portable intelligent sensing approaches. Responding to the challenges of the multiple analytes, mixtures, and complex components of practical samples, sensing array and multivariate analysis techniques have a significant advantage in terms of superior analytical capabilities, i.e., they are convenient, rapid, sensitive and have high-throughput for multi-analyte identification in food safety, clinical diagnoses, and environmental monitoring. Besides traditional molecular design and recognition mechanisms, materials with micro/nano structures also contribute to strong signals, sensitive responses, and novel properties. In this review, through a new perspective of signal amplification for responsive discrimination, we summarize progress in developing sensing arrays based on diverse micro/nanomaterials and their integrated devices for multi-analyte discrimination. An overview of strategies for constructing sensing arrays through various micro or nano building blocks, including 0D nanoparticle assembly and modification, 1D nanowires and fibers, 2D graphene and textiles, is schematized. Then, portable and wearable devices integrating colorimetric sensors or flexible electrochemical electrodes with the newest microelectronic units and circuit boards are presented. Meanwhile, the latest artificial intelligence (AI) algorithms are introduced for massive data analysis in complex biological and environmental systems. With future developments in facile and accurate discrimination for multi-analyte research, extended applications will gear up in various fields.

Graphical abstract: Multi-analyte sensing strategies towards wearable and intelligent devices

Article information

Article type
Review Article
Submitted
06 iyl 2022
Accepted
17 sen 2022
First published
24 sen 2022
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2022,13, 12309-12325

Multi-analyte sensing strategies towards wearable and intelligent devices

Y. Huang, C. Luo, F. Xia, Y. Song, L. Jiang and F. Li, Chem. Sci., 2022, 13, 12309 DOI: 10.1039/D2SC03750E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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