Issue 17, 2022

Current challenges and future applications of antibacterial nanomaterials and chitosan hydrogel in burn wound healing

Abstract

Burns are one of the most devastating skin injuries, with severe burns affecting almost every organ system, and that causes a high mortality rate. The presence of microbial infection in burn wounds makes the healing process more complex, leading to delayed wound healing. Therefore, the primary problem in treating burns is to developing antimicrobial biomaterials to overcome bacterial infection. The present review covers burn classification, the burn wound healing process, and various local treatment methods to fight infection and promote healing. We discussed the recent progress in the treatment of burn wound infection. We provided information on the application of antimicrobial materials in burn treatment in recent years, especially nanoparticles and chitosan hydrogels. We also discuss the promising future therapies for burns and the prospects and limitations for eventual translation to the clinic.

Graphical abstract: Current challenges and future applications of antibacterial nanomaterials and chitosan hydrogel in burn wound healing

Article information

Article type
Review Article
Submitted
16 iyn 2022
Accepted
24 iyl 2022
First published
27 iyl 2022
This article is Open Access
Creative Commons BY-NC license

Mater. Adv., 2022,3, 6707-6727

Current challenges and future applications of antibacterial nanomaterials and chitosan hydrogel in burn wound healing

Q. Bai, C. Zheng, W. Chen, N. Sun, Q. Gao, J. Liu, F. Hu, S. Pimpi, X. Yan, Y. Zhang and T. Lu, Mater. Adv., 2022, 3, 6707 DOI: 10.1039/D2MA00695B

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