Issue 18, 2021

Rh(iii)-Catalyzed one-pot three-component cyclization reaction: rapid selective synthesis of monohydroxy polycyclic BINOL derivatives

Abstract

A Rh(III)-catalyzed three-component C–H bond functionalization protocol has been successfully applied to access complex polycyclic BINOL derivatives in which the formation of intermediate amides occurred in situ from aldehydes and amines. The high efficiency strategy allows the rapid selective synthesis of diverse BINOL compounds in a step-economical manner from three readily accessible starting materials in one-pot.

Graphical abstract: Rh(iii)-Catalyzed one-pot three-component cyclization reaction: rapid selective synthesis of monohydroxy polycyclic BINOL derivatives

Supplementary files

Article information

Article type
Research Article
Submitted
19 may 2021
Accepted
30 iyn 2021
First published
01 iyl 2021

Org. Chem. Front., 2021,8, 4967-4973

Rh(III)-Catalyzed one-pot three-component cyclization reaction: rapid selective synthesis of monohydroxy polycyclic BINOL derivatives

H. Liu, M. Lin, Y. Chen, Y. Huang and L. Dong, Org. Chem. Front., 2021, 8, 4967 DOI: 10.1039/D1QO00779C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements