Issue 17, 2021

Lanthanide doped luminescence nanothermometers in the biological windows: strategies and applications

Abstract

The development of lanthanide-doped non-contact luminescent nanothermometers with accuracy, efficiency and fast diagnostic tools attributed to their versatility, stability and narrow emission band profiles has spurred the replacement of conventional contact thermal probes. The application of lanthanide-doped materials as temperature nanosensors, excited by ultraviolet, visible or near infrared light, and the generation of emissions lying in the biological window regions, I-BW (650 nm–950 nm), II-BW (1000 nm–1350 nm), III-BW (1400 nm–2000 nm) and IV-BW (centered at 2200 nm), are notably growing due to the advantages they present, including reduced phototoxicity and photobleaching, better image contrast and deeper penetration depths into biological tissues. Here, the different mechanisms used in lanthanide ion-doped nanomaterials to sense temperature in these biological windows for biomedical and other applications are summarized, focusing on factors that affect their thermal sensitivity, and consequently their temperature resolution. Comparing the thermometric performance of these nanomaterials in each biological window, we identified the strategies that allow boosting of their sensing properties.

Graphical abstract: Lanthanide doped luminescence nanothermometers in the biological windows: strategies and applications

Article information

Article type
Review Article
Submitted
28 dek 2020
Accepted
21 mar 2021
First published
24 mar 2021

Nanoscale, 2021,13, 7913-7987

Lanthanide doped luminescence nanothermometers in the biological windows: strategies and applications

A. Nexha, J. J. Carvajal, M. C. Pujol, F. Díaz and M. Aguiló, Nanoscale, 2021, 13, 7913 DOI: 10.1039/D0NR09150B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements