Issue 27, 2021

A dual-channel Hill-type small-molecule pH probe

Abstract

By combining a Hill-type pH probe and a pH-insensitive naphthalimide fluorophore, we synthesized a FRET-based ratiometric pH probe (PHHF), exhibiting a reduced pH transition width, representing a unique approach for development of sensitive probes for detection of biorelevant pH changes.

Graphical abstract: A dual-channel Hill-type small-molecule pH probe

Supplementary files

Article information

Article type
Communication
Submitted
23 may 2021
Accepted
16 iyn 2021
First published
16 iyn 2021

Anal. Methods, 2021,13, 3012-3016

A dual-channel Hill-type small-molecule pH probe

F. Hu, Y. Huang, Y. Xiao, Y. Li, X. Luo, X. Qian and Y. Yang, Anal. Methods, 2021, 13, 3012 DOI: 10.1039/D1AY00868D

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