Issue 1, 2018

Rationally designed meta-implants: a combination of auxetic and conventional meta-biomaterials

Abstract

Rationally designed meta-biomaterials present unprecedented combinations of mechanical, mass transport, and biological properties favorable for tissue regeneration. Here we introduce hybrid meta-biomaterials with rationally-distributed values of negative (auxetic) and positive Poisson's ratios, and use them to design meta-implants that unlike conventional implants do not retract from the bone under biomechanical loading. We rationally design and additively manufacture six different types of meta-biomaterials (three auxetic and three conventional), which then serve as the parent materials to six hybrid meta-biomaterials (with or without transitional regions). Both single and hybrid meta-biomaterials are mechanically tested to reveal their full-field strain distribution by digital image correlation. The best-performing hybrid meta-biomaterials are then selected for the design of meta-implants (hip stems), which are tested under simulated-implantation conditions. Full-field strain measurements clearly show that, under biomechanical loading, hybrid meta-implants press onto the bone on both the medial and lateral sides, thereby improving implant–bone contact and potentially implant longevity.

Graphical abstract: Rationally designed meta-implants: a combination of auxetic and conventional meta-biomaterials

Supplementary files

Article information

Article type
Communication
Submitted
30 avq 2017
Accepted
09 okt 2017
First published
18 okt 2017
This article is Open Access
Creative Commons BY-NC license

Mater. Horiz., 2018,5, 28-35

Rationally designed meta-implants: a combination of auxetic and conventional meta-biomaterials

H. M. A. Kolken, S. Janbaz, S. M. A. Leeflang, K. Lietaert, H. H. Weinans and A. A. Zadpoor, Mater. Horiz., 2018, 5, 28 DOI: 10.1039/C7MH00699C

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