Issue 20, 2017

Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

Abstract

Each day, approximately 830 women and 7400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require bringing rapid diagnosis and treatment to the point of care in low-resource settings. However, to date there are few diagnostic tools available that can be used at the point of care to detect the leading causes of maternal and neonatal mortality in low-resource settings. Here we review both commercially available diagnostics and technologies that are currently in development to detect the leading causes of maternal and neonatal mortality, highlighting key gaps in development where innovative design could increase access to technology and enable rapid diagnosis at the bedside.

Graphical abstract: Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

Article information

Article type
Critical Review
Submitted
07 apr 2017
Accepted
09 avq 2017
First published
10 avq 2017

Lab Chip, 2017,17, 3351-3387

Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

C. E. Majors, C. A. Smith, M. E. Natoli, K. A. Kundrod and R. Richards-Kortum, Lab Chip, 2017, 17, 3351 DOI: 10.1039/C7LC00374A

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