Issue 4, 2015

Toxicity of exfoliated-MoS2 and annealed exfoliated-MoS2 towards planktonic cells, biofilms, and mammalian cells in the presence of electron donor

Abstract

We demonstrate for the first time that suspensions of single-layered MoS2 nanosheets can act as photocatalytic antimicrobial materials under visible light in the presence of ethylenediaminetetraacetic acid (EDTA) as an electron donor. The antimicrobial capacity of exfoliated MoS2 (Ex-MoS2) was found to be 5.7 times higher than that of annealed exfoliated MoS2 (Ae-MoS2) against planktonic cells in the presence of 40 ppm EDTA. This difference in the antimicrobial performance was attributed to the 1T-phase of Ex-MoS2, which presents higher electron conductivity than that of Ae-MoS2. This higher electron conductivity of Ex-MoS2 led to increase generation of reactive oxygen species (ROS), as observed by the superoxide anion and hydrogen peroxide production assays under visible light. Additionally, Ex-MoS2 could also inactivate 65% of mature E. coli K12 biofilms without significant cytotoxicity to mammalian fibroblast cells. The suspension of single-layered MoS2 nanosheets opens up new opportunities for the development of advanced functional nanomaterials for biomedical and environmental applications.

Graphical abstract: Toxicity of exfoliated-MoS2 and annealed exfoliated-MoS2 towards planktonic cells, biofilms, and mammalian cells in the presence of electron donor

Supplementary files

Article information

Article type
Paper
Submitted
01 mar 2015
Accepted
18 may 2015
First published
19 may 2015

Environ. Sci.: Nano, 2015,2, 370-379

Author version available

Toxicity of exfoliated-MoS2 and annealed exfoliated-MoS2 towards planktonic cells, biofilms, and mammalian cells in the presence of electron donor

J. Fan, Y. Li, H. N. Nguyen, Y. Yao and D. F. Rodrigues, Environ. Sci.: Nano, 2015, 2, 370 DOI: 10.1039/C5EN00031A

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