Issue 8, 2013

Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs

Abstract

Floating polymeric microcapsules that simultaneously entrap multiple drugs were prepared using a solid/water/oil/water emulsion solvent evaporation method, based on harnessing interfacial phenomena and manipulation of the solvent removal process. The fabricated microcapsules exhibited excellent buoyancy in simulated gastric fluid and provided controlled and sustained release of multiple drugs for up to 24 h, thus revealing their potential as a rate-controlled oral drug delivery system.

Graphical abstract: Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs

Supplementary files

Article information

Article type
Communication
Submitted
06 dek 2012
Accepted
03 yan 2013
First published
08 yan 2013
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2013,1, 1090-1095

Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs

W. L. Lee, P. Wee, C. Nugraha and S. C. J. Loo, J. Mater. Chem. B, 2013, 1, 1090 DOI: 10.1039/C2TB00495J

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements