Issue 35, 2006
From the journal:

Chemical Communications

Fluorescent “light-up” bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics†

Hui Tong,a   Yuning Hong,a   Yongqiang Dong,ab   Matthias Häußler,a   Jacky W. Y. Lam,a   Zhen Li,a   Zufeng Guo,a   Zhihong Guoa  and  Ben Zhong Tang*ab  

* Corresponding authors

a Department of Chemistry, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, China
E-mail: tangbenz@ust.hk
Fax: +852-2358-1594
Tel: +852-2358-7375

b Department of Polymer Science and Engineering, Zhejiang University, China

Abstract

Aggregation in poor solvents and complexation with calf thymus DNA and bovine serum albumin turn “on” the fluorescence of tetraphenylethylene derivatives, due to the restriction of intra-molecular rotations of the dyes in the aggregates and complexes.

Graphical abstract: Fluorescent “light-up” bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics

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Article information

DOI
https://doi.org/10.1039/B608425G
Article type
Communication
Submitted
14 Jun 2006
Accepted
10 Jul 2006
First published
02 Aug 2006

Chem. Commun., 2006, 3705-3707

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Fluorescent “light-up” bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics

H. Tong, Y. Hong, Y. Dong, M. Häußler, J. W. Y. Lam, Z. Li, Z. Guo, Z. Guo and B. Z. Tang, Chem. Commun., 2006, 3705 DOI: 10.1039/B608425G

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