Issue 24, 2020

Design of nanoengineered antibacterial polymers for biomedical applications

Abstract

Pathogenic bacteria have become global threats to public health. Since the advent of antibiotics about 100 years ago, their use has been embraced with great enthusiasm because of their effective treatment of bacterial infections. However, the evolution of pathogenic bacteria with resistance to conventional antibiotics has resulted in an urgent need for the development of a new generation of antibiotics. The use of antimicrobial polymers offers the promise of enhancing the efficacy of antimicrobial agents. Of the various antibacterial polymers that effectively eradicate pathogenic bacteria, those that are nanoengineered have garnered significant research interest in their design and biomedical applications. Because of their high surface area and high reactivity, these polymers show greater antibacterial activity than conventional antibacterial agents, by inhibiting the growth or destroying the cell membrane of pathogenic bacteria. This review summarizes several strategies for designing nanoengineered antibacterial polymers, explores the factors that affect their antibacterial properties, and examines key features of their design. It then comments briefly on the future prospects for nanoengineered antibacterial polymers. This review thus provides a feasible guide to developing nanoengineered antibacterial polymers by presenting both broad and in-depth bench research, and it offers suggestions for their potential in biomedical applications.

Graphical abstract: Design of nanoengineered antibacterial polymers for biomedical applications

Article information

Article type
Review Article
Submitted
13 may 2020
Accepted
24 iyl 2020
First published
28 iyl 2020

Biomater. Sci., 2020,8, 6867-6882

Design of nanoengineered antibacterial polymers for biomedical applications

Q. Borjihan and A. Dong, Biomater. Sci., 2020, 8, 6867 DOI: 10.1039/D0BM00788A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements