Issue 15, 2018

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Abstract

This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has been shown to specifically image active PPIases in live cells.

Graphical abstract: A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Supplementary files

Article information

Article type
Communication
Submitted
28 noy 2017
Accepted
23 yan 2018
First published
23 yan 2018

Chem. Commun., 2018,54, 1857-1860

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Q. Jiang, X. Li, C. Wang, J. Cheng, C. Tan, T. Cui, N. Lu, T. D. James, F. Han and X. Li, Chem. Commun., 2018, 54, 1857 DOI: 10.1039/C7CC09135D

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