View PDF Version
 
DOI: 10.1039/A802212G (Paper) Reference Section for: J. Chem. Soc., Perkin Trans. 2, 1998, 1283-1286

Comparative study of the protection of modified and unmodified dsDNA by cationic and non-cationic lipids and liposomes to digestion by DNase I

(Note: The full text of this document is currently only available in the PDF Version )

Marta Legido and Chris Abell

Abstract

A comparative study of the protection of dsDNA by cationic and non-cationic lipids and liposomes from degradation by DNase I reveals formulation-dependent differences in protection.

References

  1. J. F. Milligan, M. O. Matteucci and J. C. Martin, J. Med. Chem., 1993, 36, 1923 CrossRef CAS .
  2. C. McKellar, D. Graham, D. W. Will, S. Burgess and T. Brown, Nucleic Acids Res., 1992, 20, 3411 .
  3. E. Uhlmann and A. Peyman, Chem. Rev., 1990, 90, 543 CrossRef CAS .
  4. M. Manoharan, L. K. Johnson, C. F. Benner, T. A. Vickers, D. J. Ecker, L. M. Cowsert, S. M. Freier and P. D. Cook, Bioorg. Med. Chem. Lett., 1994, 4, 1053 CrossRef CAS .
  5. P. K. Nandi, A. Legrand and C. Nicolau, J. Biol. Chem., 1986, 261, 16 722 CAS ; P. L. Felgner and G. M. Ringold, Nature, 1989, 337, 387 CrossRef .
  6. H. M. Deshmukh and L. Huang, New J. Chem., 1997, 21, 113 Search PubMed .
  7. P. L. Felgner, Adv. Drug Delivery Rev., 1990, 5, 163 CrossRef CAS .
  8. C. Puyal, P. Milhaud, A. Bienvenue and J. R. Philippot, Eur. J. Biochem., 1995, 228, 697 CAS .
  9. V. L. Singer, L. J. Jones, S. T. Yue and R. P. Haugland, Anal. Biochem., 1997, 249, 228 CrossRef CAS .
  10. J. M. Tomkins, K. J. Barnes, A. J. Blacker, W. J. Watkins and C. Abell, Tetrahedron Lett., 1997, 38, 691 CrossRef CAS .
  11. R. T. Fraley, C. S. Fornari and S. P. Kaplan, Proc. Natl. Acad. Sci. USA, 1979, 76, 3348 CAS ; M. J. Ostro, D. Giacomoni, D. Lavelle, W. Paxton and S. Dray, Nature, 1978, 274, 921 CAS ; G. J. Dimitriadis, Nature, 1978, 274, 923 CAS .
  12. R. R. C. New, Liposomes a Practical Approach, IRL Press, Oxford, 1990, p. 33 Search PubMed .