On the physical processes of mechanochemically induced transformations in molecular solids

Adam A. L. Michalchuk

Chem. Commun., 2024, 60, 14750
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In situ Raman spectroscopy for comparing ball milling and resonant acoustic mixing in organic mechanosynthesis

Leonarda Vugrin, Christos Chatzigiannis, Evelina Colacino and Ivan Halasz

RSC Mechanochem., 2025, 2, 482
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Synthesis of organic HCl salts via mechanochemical salification and their characterization with 35/37Cl solid-state NMR spectroscopy

Zachary T. Dowdell, Peyton G. Osborn, Victoria K. Rash, Trisha S. Patel, Alexander M. Perez, Xinsong Lin, Sean T. Holmes and Robert. W. Schurko

RSC Mechanochem., 2026
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Scalable depolymerizing transesterification and amidation of (poly)lactic acid (PLA) enabled by resonant acoustic mixing (RAM)

Anton S. Makarov and Magnus Rueping

Green Chem., 2025, 27, 716
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Tailored hybridization of MIL-101(Cr) with graphene oxide enables enhanced hydrogen storage and delivery

Laura Jimenez Lopez, Rafael Morales-Ospino, Rosana V. Pinto, Jimena Castro-Gutierrez, Georges Mouchaham, Alain Celzard, Christian Serre and Vanessa Fierro

J. Mater. Chem. A, 2026, 14, 3101
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More than “just a drop”: the enigmatic role of liquid additives in mechanochemistry

Ilenia D'Abbrunzo and Dritan Hasa

CrystEngComm, 2026, 28, 1752
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Halogen-bonded cocrystals via resonant acoustic mixing

Alireza Nari, Jeffrey S. Ovens and David L. Bryce

RSC Mechanochem., 2024, 1, 50
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Mechanochemical synthesis of phthalimides from terpenes via tandem Diels-Alder cycloaddition and iodine-mediated aromatization

Jhully Anne Barros Carvalho Ribeiro, Renan Rodini Mattioli, Duncan L. Browne and Julio C. Pastre

RSC Sustainability, 2025, 3, 5601
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A mechanochemical [2+2+2] cycloaddition facilitated by a cobalt(ii) catalyst and piezoelectric materials

Kalipada Jana, Koji Kubota and Hajime Ito

Chem. Sci., 2025, 16, 11468
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The role of the milling environment on the copper-catalysed mechanochemical synthesis of tolbutamide

Kathleen Floyd, Lori Gonnet, Tomislav Friščić and James Batteas

RSC Mechanochem., 2024, 1, 289
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One-pot mechanochemical access to quinoline-linked covalent organic frameworks

Yizhou Zhan, Yuxuan Yang, Wei Zhao, Xi Wang, Jiarong Qiu, Zhaonan Tang, Jiao He, Chenglong Deng, Heshen Xiao, Yiying Pang and Xiaoji Wang

RSC Adv., 2026, 16, 20609
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Scratching beneath the surface: catalyst evolution and reusability in the direct mechanocatalytic Sonogashira reaction

Sheeniza Shah, Mennatullah M. Mokhtar, Thinh Tran, Kathleen Floyd, Lizette Mella, Tim Dao, Alexandria Garza, James Batteas and James Mack

RSC Mechanochem., 2026, 3, 46
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Towards greener-by-design fine chemicals. Part 1: synthetic frontiers

Theodore A. Gazis, Jonas Wuyts, Areti Moutsiou, Giulio Volpin, Mark J. Ford, Rodolfo I. Teixeira, Katherine M. P. Wheelhouse, Philipp Natho, Polona Žnidaršič-Plazl, Sonja Jost, Renzo Luisi, Brahim Benyahia, Bert U. W. Maes and Gianvito Vilé

Chem. Soc. Rev., 2026, 55, 619
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Ligand-free reductive amination via Pd-coated mechanocatalysis

Maximilian Wohlgemuth, Sarah Schmidt, Lars Beißel and Lars Borchardt

Chem. Commun., 2025, 61, 18838
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Moving mechanochemistry forward

James Batteas, Kerstin G. Blank, Evelina Colacino, Franziska Emmerling, Tomislav Friščić, James Mack, Jeffrey Moore, Maria Elena Rivas and Wilfred Tysoe

RSC Mechanochem., 2025, 2, 10
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Synthesis of short DNA and RNA fragments by resonant acoustic mixing (RAM)

James D. Thorpe, Julian Marlyn, Stefan G. Koenig and Masad J. Damha

RSC Mechanochem., 2024, 1, 244
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Harnessing the copper surface for direct mechanocatalysis: a case study on mechanochemical sulfonylurea synthesis

Kathleen R. Floyd, Lizette S. Mella, Ryan W. Kwok, Mackenzie Gray, Edward J. Broker, Mateusz Marianski, Tomislav Friščić and James D. Batteas

Chem. Sci., 2025, 16, 19830
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Mechanochemical aerobic oxidative Heck coupling by polymer-assisted grinding: cyclodextrin additive facilitating regioselectivity control

Keyu Xiang, Haowen Shou, Chenhui Hu, Weike Su and Jingbo Yu

Green Chem., 2024, 26, 5890
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Salient Achievements in Synthetic Organic Chemistry Enabled by Mechanochemical Activation

Eusebio Juaristi and C. Gabriela Avila-Ortiz

Synthesis, 2023, 55, 2439
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Photochemical Stabilization of Self‐Assembled Spherical Nucleic Acids

Sepideh Kaviani, Haochen Bai, Trishalina Das, Jathavan Asohan, Abdelrahman Elmanzalawy, Julian Marlyn, Lea El Choueiri, Masad J. Damha, Quentin Laurent and Hanadi F. Sleiman

Small, 2025, 21
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Mechanochemical and Transition-Metal-Catalyzed Reactions of Alkynes

Lifen Peng, Zhiling Zou, Ting Wang, Xirong Liu, Hui Li, Zhiwen Yuan, Chunling Zeng, Xinhua Xu, Zilong Tang and Guofang Jiang

Catalysts, 2025, 15, 690
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Engineering uniformly dispersed micro/nano aramid fiber networks via acoustic resonance mixing at the interlayers of basalt fiber composites: A significant leap in interlaminar toughness

Shulan Jiang, Weiwei Yu, Hao Ma, Guanghui Zhu and Xiaobin Zhan

Composites Communications, 2025, 60, 102613
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In-situ monitoring of polymer mechanochemistry: what can be learned from small molecule systems

Niamh Willis-Fox

Front. Chem., 2024, 12
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Calcium Carbide (CaC2) as a C2‐Synthon by Mechanochemistry

Alejandro Cortés‐Lobo and José G. Hernández

ChemPlusChem, 2024, 89
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Process Integration and Life‐Cycle Assessment of Moist‐Solid Hydrolysis of Polylactic Acid with Lactic Acid Recovery via Electrodialysis

Hui Luo, Dingchang Yang, Jhuma Sadhukhan, Verdeluz Costica, Robert Dorey, Qilei Song and Maria‐Magdalena Titirici

ChemSusChem, 2025, 18
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Research on the microscopic acoustic streaming mechanism of power-law non-Newtonian fluids in resonant acoustic mixing

Qiang Huo, Xiaopeng Wang and Yuqi Gao

Chemical Engineering Science, 2026, 320, 122401
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Recent advances in mechanochemical metal-catalyzed cross-coupling reactions

Suman Yadav and Radovan Šebesta

Tetrahedron Chem, 2026, 18, 100158
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Shaking Up the Friedländer Reaction: Rapid, Scalable Mechanochemical Synthesis of Polyaryl‐Substituted Quinolines

Daliah Farajat, Jean‐Louis Do, Pat Forgione, Tomislav Friščić, Louis A. Cuccia and Chao‐Jun Li

Adv Synth Catal, 2024, 366, 5135
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Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

Johanna Breinsperger, Nika Podlesnik, Francesco Mele and Michael Schnürch

Chemistry A European J, 2026, 32
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Formation of Racemic Phases of Amino Acids by Liquid-Assisted Resonant Acoustic Mixing Monitored by Solid-State NMR Spectroscopy

Leeroy Hendrickx, Calogero Quaranta, Emilian Fuchs, Maksim Plekhanov, Mirijam Zobel, Carsten Bolm and Thomas Wiegand

Molecules, 2025, 30, 3745
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How to Track Mechanochemical Reactions in Resonant Acoustic Mixers by in Situ Raman Spectroscopy

Steffi Krause Hinojosa, Tugce Dogan, Sven Fabig, Sven Grätz and Lars Borchardt

Chemistry A European J, 2025, 31
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Milling Medium‐Free Suzuki Coupling by Direct Mechanocatalysis: From Mixer Mills to Resonant Acoustic Mixers**

Maximilian Wohlgemuth, Sarah Schmidt, Maike Mayer, Wilm Pickhardt, Sven Grätz and Lars Borchardt

Chemistry A European J, 2023, 29
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Molecular Recognition in Mechanochemistry: Insights from Solid‐State NMR Spectroscopy

Calogero Quaranta, Igor d'Anciães Almeida Silva, Sven Moos, Ettore Bartalucci, Leeroy Hendrickx, Benjamin M. D. Fahl, Claudia Pasqualini, Francesco Puccetti, Mirijam Zobel, Carsten Bolm and Thomas Wiegand

Angewandte Chemie, 2024, 136
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Mechanochemical Mitsunobu Reactions

Matthew T. J. Williams, Laura Adarve Cardona and Carsten Bolm

Adv Synth Catal, 2024, 366, 2220
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Rapid and scalable ruthenium catalyzed meta-C–H alkylation enabled by resonant acoustic mixing

Arnab Dey, Rajesh Kancherla, Kuntal Pal, Nathan Kloszewski and Magnus Rueping

Commun Chem, 2024, 7
DOI: 10.1038/s42004-024-01390-1

Shaking Up Photochemistry: The Future Frontiers of Mechanophotocatalysis

Francis Millward and Eli Zysman-Colman

ACS Cent. Sci., 2026, 12, 17
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Intermediates in Mechanochemical Reactions

Karen J. Ardila‐Fierro and José G. Hernández

Angewandte Chemie, 2024, 136
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Mechanochemical Synthesis of Boroxine‐linked Covalent Organic Frameworks

Ehsan Hamzehpoor, Farshid Effaty, Tristan H. Borchers, Robin S. Stein, Alexander Wahrhaftig‐Lewis, Xavier Ottenwaelder, Tomislav Friščić and Dmytro F. Perepichka

Angew Chem Int Ed, 2024, 63
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Mechanochemistry: Looking back and ahead

Tomislav Stolar, Jasna Alić, Lucia Casali, Nikita Gugin, Matej Baláž, Adam A.L. Michalchuk and Franziska Emmerling

Chem, 2026, 12, 102880
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Synthesis of Quinazolinones and Benzothiazoles Using α-Keto Acids under Ball Milling

Anoop Sharma, Jitender Singh and Anuj Sharma

J. Org. Chem., 2024, 89, 5229
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Molecular Recognition in Mechanochemistry: Insights from Solid‐State NMR Spectroscopy

Calogero Quaranta, Igor d'Anciães Almeida Silva, Sven Moos, Ettore Bartalucci, Leeroy Hendrickx, Benjamin M. D. Fahl, Claudia Pasqualini, Francesco Puccetti, Mirijam Zobel, Carsten Bolm and Thomas Wiegand

Angew Chem Int Ed, 2024
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Mechanochemically Synthesized Amidetriazoles for Effective Optical and Electrochemical Detection of Anions

Jakub S. Cyniak, Daria Szeląg, Róża Sitek, Wojciech Wróblewski and Artur Kasprzak

J. Org. Chem., 2026, 91, 4945
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Intermediates in Mechanochemical Reactions

Karen J. Ardila‐Fierro and José G. Hernández

Angew Chem Int Ed, 2024, 63
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Solid‐State Oxidation of Alcohols in Gold‐Coated Milling Vessels via Direct Mechanocatalysis

Maximilian Wohlgemuth, Sarah Schmidt, Maike Mayer, Wilm Pickhardt, Sven Graetz and Lars Borchardt

Angew Chem Int Ed, 2024, 63
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Opportunities and Challenges in Applying Solid‐State NMR Spectroscopy in Organic Mechanochemistry

Igor d'Anciães Almeida Silva, Ettore Bartalucci, Carsten Bolm and Thomas Wiegand

Advanced Materials, 2023, 35
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Synergistic effects of fluorination on CO2 capture and activation in 1,2,3-triazolium ionic liquids

Gustavo Chacón-Rosales, Cristián Valdebenito, Karina Muñoz-Becerra, Carlos Cruz, Cesar Morales-Verdejo, Kerry Wrighton-Araneda, Pedro Aguirre and Gabriel Abarca

Journal of CO2 Utilization, 2025, 100, 103178
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Mechanochemical Synthesis of Boroxine‐linked Covalent Organic Frameworks

Ehsan Hamzehpoor, Farshid Effaty, Tristan H. Borchers, Robin S. Stein, Alexander Wahrhaftig‐Lewis, Xavier Ottenwaelder, Tomislav Friščić and Dmytro F. Perepichka

Angewandte Chemie, 2024, 136
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Discrete element method study of the impact of vessel wall friction on the mixing dynamics of a resonant acoustic mixer

Jack R. Grogan, Tomislav Friščić, Nicholas Bazin, Peter Bolton and Christopher R.K. Windows-Yule

Powder Technology, 2026, 479, 122499
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Sustainable click reactions: Use of greener reaction media in the synthesis of 1,2,3-triazoles

Luan A. Martinho and Carlos Kleber Z. Andrade

Tetrahedron, 2024, 157, 133964
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N-Heterocyclic Carbene Deposition on a Copper Powder Surface Using Mechanochemistry

Jéssica S. G. Selva, Yuanjiao Li, Jashanpreet Kaur, Antoine Juneau, Ahmad Diraki, Souhaila Bendahmane, Jeffrey D. Henderson, Mark D. Aloisio, Anastasia Messina, Ahmadreza Nezamzadeh, Camilo J. Viasus Pérez, Mark C. Biesinger, Annie Levasseur, Cathleen M. Crudden and Janine Mauzeroll

ACS Appl. Mater. Interfaces, 2025, 17, 10004
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A scalable photo-mechanochemical platform for sustainable photoredox catalysis by resonant acoustic mixing

Deshen Kong, Liang Yi, Alice Nanni and Magnus Rueping

Nat Commun, 2025, 16
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Solid‐State Photochemistry in Resonant Acoustic Mixers

Carolina Spula, Phil M. Preuß, Lars Borchardt and Sven Grätz

Chemistry A European J, 2025, 31
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Chemical and Enzymatic Mechanosynthesis of Organocatalytic Peptide Materials Based on Proline and Phenylalanine

Alexandra Rios‐Echeverri, Carlos E. Puerto Galvis, Karen J. Ardila‐Fierro and José G. Hernández

ChemSusChem, 2025, 18
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Multigram‐Scale Organic Synthesis by Resonant Acoustic Mixing: Application to the Sustainable Preparation of Active Pharmaceutical Ingredients

Christos M. Chatzigiannis, Stefania M. Scalzullo, Evelina Colacino and Maria Elena Rivas

ChemSusChem, 2025, 18
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Deoxygenative Route to Alkynylation of Heterocyclic N-Oxides under Ball Milling

Ajay Kumar Dhiya, Manpreet Kaur and Anuj Sharma

J. Org. Chem., 2025, 90, 11033
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From Micro to Marvel: Unleashing the Full Potential of Click Chemistry with Micromachine Integration

Zihan Chen, Zimo Ren, Carmine Coluccini and Paolo Coghi

Micromachines, 2025, 16, 712
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Festphasen‐Alkoholoxidation mittels Direkter Mechanokatalyse

Maximilian Wohlgemuth, Sarah Schmidt, Maike Mayer, Wilm Pickhardt, Sven Graetz and Lars Borchardt

Angewandte Chemie, 2024, 136
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Emergence of radial particle size segregation in vibrated size-disperse granular materials

S. Emad Renfroe, Blair K. Brettmann, Jeremy B. Lechman and Joseph M. Monti

Chemical Engineering Research and Design, 2026, 227, 965
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Energy Distribution during Resonant Acoustic Mixing

Preston D. Silverstein, Ehsan Madadi-Kandjani and Joseph Kalman

ACS Omega, 2025, 10, 42323
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