Ginsenoside Rb2 exhibits therapeutic value for male osteoporosis in orchiectomy mice by suppressing osteoclastogenesis and modulating NF-κB/MAPK signaling pathways

Yanhuai Ma, Jianliang Li, Jiale Mai, Huizhi Guo, Lingli Ding, Jinglan Li, Jiacong Xiao, Miao Li, Weihua Fang, Shuncong Zhang, Liangliang Xu and Haibin Wang

Food Funct., 2024, 15, 1583
DOI: 10.1039/D3FO04334G

How to More Effectively Obtain Ginsenoside Rg5: Understanding Pathways of Conversion

Leqin Cheng, Wei Luo, Anqi Ye, Yuewei Zhang, Ling Li and Haijiao Xie

Molecules, 2023, 28, 7313
DOI: 10.3390/molecules28217313

The history, beneficial ingredients, mechanism, processing, and products of Panax ginseng for medicinal and edible value

Zhu-Bin Zhang, Chen-Yu Yu, Hua-Ying Wang, Xiao-Bin Jia, Wei Wu, Shi-Ting Pang, Wei Li, Sana Zahoor, Waliullah Khan, Yan-Cheng Liu, Bing Yang and Liang Feng

Food & Medicine Homology, 2025, 2, 9420059
DOI: 10.26599/FMH.2025.9420059

Advances in Modern Medical Research on the Hematopoietic Effect of Qi and Blood Replenishing Drugs

爽爽段

MD, 2025, 15, 123
DOI: 10.12677/md.2025.151017

Four-Dimensional Label-Free Quantitative Proteomics of Ginsenoside Rg2 Ameliorated Scopolamine-Induced Memory Impairment in Mice through the Lysosomal Pathway

Pei Yin, Heyu Wang, Tingfang Xue, Xiaoran Yu, Xingjian Meng, Qianwen Mi, Shixin Song, Boyu Xiong, Yunfeng Bi and Lei Yu

J. Agric. Food Chem., 2024, 72, 14640
DOI: 10.1021/acs.jafc.4c00181

Combined network pharmacology and metabolomics reveal that Rubia cordifolia L. ameliorates exhaustive exercise-induced myocardial injury in rats via the BCAA degradation pathway

Xueyu Niu, Jia Deng, Yan Zhao, Yi Zhang, Ziqi Wang, Li Zhang and Kan Wang

Fitoterapia, 2025, 184, 106617
DOI: 10.1016/j.fitote.2025.106617

Research progress on anti-aging effects and mechanisms of the new ginsenoside Compound K

Zhiqin Fang, Jingyin Zhang, Jianwen Huang and Shuibin Cen

Journal of Dermatologic Science and Cosmetic Technology, 2025, 2, 100072
DOI: 10.1016/j.jdsct.2025.100072

Botanical Nanovesicles Boost Mesenchymal Stem Cell Therapy: Next-Gen Advanced Therapy Medicinal Products for Spinal Cord Injury

Zhe Wang, Wenwen Deng, Qingtong Yu, Jiangnan Yu and Ximing Xu

Tissue Engineering Part B: Reviews, 2026
DOI: 10.1177/19373341251372972

Dietary ginsenosides for longevity: from biosynthesis and bioactive potential to functional food applications

Chao Fang, Yujie Zhao, Haixia Yang, Daidi Fan and Jianjun Deng

Critical Reviews in Food Science and Nutrition, 2026, 1
DOI: 10.1080/10408398.2026.2652525

Integrating tradition and innovation: Health industry opportunities for ginseng with foods and medicines

Wei Li

Chinese Herbal Medicines, 2024, 16, 487
DOI: 10.1016/j.chmed.2024.09.007

Preparation and characterisation of palm-based tocotrienol-carotenoid emulsion stabilised by hemp protein isolate-ginsenoside emulsifier

Mingyang Cui, Tai Boon Tan, Ming Fu, Ziyang Cheng, Masni Mat Yusoff and Chin Ping Tan

IFRJ, 2025, 32, 889
DOI: 10.47836/ifrj.32.3.22

Ginsenoside Rg2 ameliorates metabolic dysfunction-related steatohepatitis via the Nrf2 pathway by suppressing inflammation, apoptosis, oxidative stress and fibrosis

Jiabing Chen, Xiaoqin Wu, Tingting Chen, Tianqi Cui, Dailin Wu, Min Qiu, Qincheng Yi, Ziyi Zhang, Chenlu Ma, Yong Gao, Yinliang Zhang, Zhuohui Luo and Jiawen Huang

Phytomedicine, 2025, 149, 157552
DOI: 10.1016/j.phymed.2025.157552

Challenges of continuous cropping obstacles in Panax ginseng: Formation and response mechanisms

Kang Chen, Yuru Tong, Tielin Wang, Xiuteng Zhou, Junhui Zhou, Yang Ge, Han Zheng, Muyao Yu, Yunfeng Luo and Ruifeng Ji

Sci Tradit Chin Med, 2025, 3, 8
DOI: 10.1097/st9.0000000000000058

Notoginsenoside R1 mitigates UVB-induced skin sunburn injury through modulation of N4-acetylcytidine and autophagy

Shuyun Liang, Xiaokang Liu, Yuting Yang, Fangyuan Zhang, Xiaobo Sun, Tong Zhang, Dean Guo, Jiyu Gong and Zizhao Yang

Chin Med, 2025, 20
DOI: 10.1186/s13020-025-01270-3

Multi-omics to hormonal signaling networks: Decoding growth-defense trade-offs underlying growth-retardation in two-year-old cultivated ginseng (Panax ginseng C.A. Mey.)

Ying Yang, Chengcai Zhang, Yapeng Wang, Junhui Zhou, Yutong Hua, Xiuteng Zhou, Han Zheng, Xiaoli Ma, Yang Ge, Bowen Qiu, Yufeng Xiong, Ruifeng Ji, Muyao Yu, Yunfeng Luo, Yuru Tong, Luqi Huang and Kang Chen

Industrial Crops and Products, 2025, 236, 121873
DOI: 10.1016/j.indcrop.2025.121873

Ginsenosides in Modern Pharmaceutics: Mechanisms, Applications, Challenges, and Perspectives

Mingyang Sun, Youduan Li, Ming Zhu, Haoming Luo and Ye Teng

Biomolecules, 2026, 16, 350
DOI: 10.3390/biom16030350

Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression

Chen Guo, Ming-xia Wu, Ze-peng Zhang, Jing Li, Jin-jin Chen, Hang Su, Kun Wei, Da-qing Zhao, Xiang-yan Li and Qing-xia Huang

Journal of Ginseng Research, 2025, 49, 541
DOI: 10.1016/j.jgr.2025.05.001

Co-assembly strategies of natural plant compounds for improving their bioavailability

Yu-Hang Miao, Xin Wang, Xiao-Min Zhao, Yan-Wei Hu, Xin Liu and Da-Wei Deng

Food & Medicine Homology, 2025, 2, 9420022
DOI: 10.26599/FMH.2025.9420022

Investigating mechanisms of Sophora davidii (Franch.) skeels flower extract in treating LPS-induced acute pneumonia based on network pharmacology

Ping Chen, Cheng Lin, Qi Jin, Baibai Ye, Xinxu Liu, Keke Wang, Han Zhang, Jiahui Liu, Runan Zhang, Hao Huang, Chenning Zhang and Linfu Li

Journal of Ethnopharmacology, 2025, 337, 118914
DOI: 10.1016/j.jep.2024.118914

Treatment of Insomnia With Traditional Chinese Medicine Presents a Promising Prospect

Boyi Zhang, Qianqian Wang, Yuhang Zhang, Hanyu Wang, Jingyu Kang, Yandi Zhu, Baiyan Wang and Shuying Feng

Phytotherapy Research, 2025, 39, 2724
DOI: 10.1002/ptr.8495

Effect and mechanism of Chinese medicine on inhibiting the senescence of mesenchymal stem cells

Jianjian Zhuang, Wenjie Yang, Yiming Jiang, Yang Chen, Xiaoli Ye, Yangling Li and Nengming Lin

Chinese Journal of Natural Medicines, 2026, 24, 1
DOI: 10.1016/S1875-5364(26)61072-2

Rosa roxburghii Fruit Extracts Upregulate Telomerase Activity and Ameliorate Cell Replicative Senescence

Yan Huang, Haoyue Peng, Yifan Wu, Shengcheng Deng, Fahuan Ge, Wenbin Ma, Xue Zhou and Zhou Songyang

Foods, 2024, 13, 1673
DOI: 10.3390/foods13111673

Bifunctional pectin-silica nanocomposites for mitigating drought stress and promoting ginseng growth

Yanghong Liu, Tong Wu, Kaixuan Wang, Jialong He, Jiaheng Li, Yingping Wang, Chen Xu and Kai Dong

International Journal of Biological Macromolecules, 2026, 335, 149329
DOI: 10.1016/j.ijbiomac.2025.149329

Ginsenoside-based nanoliposomes co-delivering ergothioneine and coenzyme Q10 to combat skin aging via mitochondrial modulation

Shining Li, Ying Luo, Dan Wang, Bingqing Wang, Jun Gao, Xin Chen, Zhigang Li, Haixiao Wan, Ying Wu, Zhuang Ma, Yongjie Lu, Lin Geng, Yan Huang, Na Li, Li Ye, Dongcui Li and Naisheng Jiang

Colloids and Surfaces B: Biointerfaces, 2026, 260, 115405
DOI: 10.1016/j.colsurfb.2025.115405

Ginsenoside Rg5 mitigates tenocyte death via SIRT6/autophagy-dependent signaling in an aging model

Do Su Lim, Sung Ho Ahn, Wonjun Cho, Hyeon Ji Gwon, Jun Hwi Ko, Min Kyung Pyo, A.M. Abd El-Aty, Soon Auck Hong, Jong Wook Shin, Ji Hoon Jeong and Tae Woo Jung

Journal of Ginseng Research, 2026, 50, 100921
DOI: 10.1016/j.jgr.2025.11.009

Ginseng as promising natural medicine against infectious diseases: Therapeutic targets and potential mechanisms

Yuemeng Song, Shanshan Zhang, Ruyue Wang, Yanan Zhang, Yuhan Zhang, Hongqiang Lin and Fang Wang

Journal of Ethnopharmacology, 2026, 356, 120764
DOI: 10.1016/j.jep.2025.120764

Novel cocktail therapy based on multifunctional supramolecular hydrogel targeting immune-angiogenesis-nerve network for enhanced diabetic wound healing

Ruiyin Zeng, Yuan Xiong, Ze Lin, Xiangyu Chu, Bin Lv, Li Lu, Chuanlu Lin, Jiewen Liao, Lizhi Ouyang, Yun Sun, Guandong Dai, Faqi Cao and Guohui Liu

J Nanobiotechnol, 2024, 22
DOI: 10.1186/s12951-024-03038-7

Characterization and association patterns of Chinese food–medicine homologous species based on big data analytics

Yaqun Liu, Chunjuan Zhou, Yukai Wan, Yongping Huang, Lianghui Chen, Yu Yang, Biting Fang, Zhenxia Zhang, Chengsong Xie, Yicun Chen, Mouquan Liu and Yuzhong Zheng

J Sci Food Agric, 2025, 105, 4808
DOI: 10.1002/jsfa.14210

THz spectral classification of medicine-food homology substances with transformer-CNN

Yuying Jiang, Shilei Wei, Syed Tauseef Abbas Gilani, Hongyi Ge, Xixi Wen, Shun Wang, Xi Jin, Huifang Zheng, Peng Li and Yitong Zhou

Infrared Physics & Technology, 2026, 155, 106503
DOI: 10.1016/j.infrared.2026.106503

EGCG Mitigates Apoptosis of Lens Epithelial Cells in Age-Related Cataract via the PAK1/Cleaved Caspase-3 Pathway

Yue Zhang, Dongmei Su, Zhaoyi Sun, Yanjiang Fu, Xiaoya Chen, Yuzhu Hu, Xiao Zhang, Shunfei Zheng, Xu Ma and Shanshan Hu

CMM, 2025, 25, 1269
DOI: 10.2174/0115665240334265250213064823

The Effects of Low-Temperature Stress on the Physiological Characteristics and Active Components of Ginseng Under Different Soil Moisture Conditions

Jiao Liu, Hongyan Jin, Yingping Wang, Xiaoying Liu, Yonghua Xu and He Yang

Horticulturae, 2025, 11, 526
DOI: 10.3390/horticulturae11050526

Advances in the Identification Methods of Food-Medicine Homologous Herbal Materials

Yuying Jiang, Shilei Wei, Hongyi Ge, Yuan Zhang, Heng Wang, Xixi Wen, Chunyan Guo, Shun Wang, Zhikun Chen and Peng Li

Foods, 2025, 14, 608
DOI: 10.3390/foods14040608

Biochemical insights into specialized plant metabolites: Advancing cosmeceutical applications for skin benefits

Amine Elbouzidi, Mounir Haddou, Abdellah Baraich, Mohamed Taibi, Naoufal El Hachlafi, Ashutosh Pareek, François Mesnard and Mohamed Addi

Journal of Agriculture and Food Research, 2025, 19, 101651
DOI: 10.1016/j.jafr.2025.101651

The battle against skin aging: Advances in natural anti-aging compounds and innovative delivery systems

Shuhan Zhang, Xinyue Guo, Longhui Hao, Yu Jiang, Zhiyang Chen, Jia Wang, Liuyi Ran, Yanfang Yang, Hongliang Wang, Yannian Wang, Jun Ye and Yuling Liu

Chinese Chemical Letters, 2026, 37, 112503
DOI: 10.1016/j.cclet.2026.112503

Cordycepin extends the longevity of Caenorhabditis elegans via antioxidation and regulation of fatty acid metabolism

Yang Sun, Mengling Zhong, Jingjie Wang, Mingmei Feng, Caihong Shen, Zhipeng Han, Xiaonian Cao and Qi Zhang

European Journal of Pharmacology, 2025, 994, 177388
DOI: 10.1016/j.ejphar.2025.177388

Separation and detection of ginsenosides: Challenges, industrial implications, and developments

Anqi Liu, Junjun Zhou, Yiling Luo, Yingbo Li, Yu Yang, Zibo Meng, Lixia Zhou, Hanlei Zhang, Na Liu, Ming Hui, Dandan Zhai and Peng Li

Food Research International, 2025, 221, 117069
DOI: 10.1016/j.foodres.2025.117069

Structural Characters and Pharmacological Activity of Protopanaxadiol‐Type Saponins and Protopanaxatriol‐Type Saponins from Ginseng

Lancao Zhang, Xiang Gao, Chunhui Yang, Zuguo Liang, Dongsong Guan, Tongyi Yuan, Wenxiu Qi, Daqing Zhao, Xiangyan Li, Haisi Dong, He Zhang and Norsharina Ismail

Advances in Pharmacological and Pharmaceutical Sciences, 2024, 2024
DOI: 10.1155/2024/9096774

Natural Modulators of Key Signaling Pathways in Skin Inflammageing

Qianqian Ren, Liping Qu, Yonglei Yuan and Feifei Wang

CCID, 2024, Volume 17, 2967
DOI: 10.2147/CCID.S502252

Hyperspectral imaging combined with genetic algorithm-optimized machine learning for the rapid and nondestructive quantification of ginsenosides and polysaccharides in Panax ginseng

Hui Xu, Meixin Chen, Yuting You, Xueyuan Bai and Wei Zhang

Journal of Food Composition and Analysis, 2026, 149, 108615
DOI: 10.1016/j.jfca.2025.108615

Aqueous Polygalae Radix extract (PRE) prolongs the lifespan of C. elegans and alleviates D-galactose-induced oxidative stress in the mouse liver and brain by modulating PPARγ/MAPK

Jiaqi Zhang, Wenxue Zheng, Zhengjie Zhou, YiMing An, Haoyu Zheng, Yanan Zhang, Yuchen Wei, Qianhua Zhang, Jingtong Zheng and Fang Wang

Journal of Ethnopharmacology, 2025, 348, 119878
DOI: 10.1016/j.jep.2025.119878

Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases

Mingyu Wu, Ke Li, Jiabin Wu, Xianyi Ding, Xiaotong Ma, Wenhong Wang and Weihua Xiao

Pharmacological Research, 2025, 212, 107571
DOI: 10.1016/j.phrs.2024.107571

Review on ginseng and its potential active substance G-Rg2 against age-related diseases: Traditional efficacy and mechanism

Yu-zhuo Zhang, De-yang Huo, Zhi Liu, Xin-dian Li, Zi Wang and Wei Li

Journal of Ethnopharmacology, 2025, 337, 118781
DOI: 10.1016/j.jep.2024.118781

Trends in intestinal aging: From underlying mechanisms to therapeutic strategies

Yajun Wang, Xueni Zhang, Mengli Qing, Wen Dang, Xuemei Bai, Yingjie Wang, Di Zhou, Lingjuan Zhu, Degang Qing, Juan Zhang, Gang Chen and Ning Li

Acta Pharmaceutica Sinica B, 2025, 15, 3372
DOI: 10.1016/j.apsb.2025.05.011

Immunomodulatory functions of ginsenosides in skin diseases: molecular mechanisms and therapeutic prospects

Donglin Yuan, Jiaxin Li, Zian Wang, Yu Han, Xue Yu, Zhendong Wei and Binbin Hou

Front. Pharmacol., 2026, 17
DOI: 10.3389/fphar.2026.1783370

Anti-Aging and Anti-Inflammatory Effects of Compounds from Fresh Panax ginseng Roots: A Study on TNF-α/IFN-γ-Induced Skin Cell Damage

Minseo Kang, Somin Park, So-Ri Son, Yedam Noh, Dae Sik Jang and Sullim Lee

Molecules, 2024, 29, 5479
DOI: 10.3390/molecules29225479