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The influence of coordination compounds with malatogermanate/stannate anions and 1,10-phenanthroline cations of 3D metals on α-L-rhamnosidase activity of Penicillium tardum, Penicillium restrictum and Eupenicillium erubescens
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Engineering of methionine sulfoxide reductase A with simultaneously improved stability and activity for kinetic resolution of chiral sulfoxides
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Integration of Medium Engineering, Immobilization, and Rotating Bed Reactor for Intensifying Enzymatic Reduction of Halogenated Aryl Ketones
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An Update: Enzymatic Synthesis for Industrial Applications
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Mining and Engineering the Di-O-glycosylation Pattern of UGT72B1 for the Highly Efficient O-Glycosylation of Endogenous Quercetin
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Application of Immobilized Enzymes in Flow Biocatalysis for Efficient Synthesis
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Practical Machine Learning-Assisted Design Protocol for Protein Engineering: Transaminase Engineering for the Conversion of Bulky Substrates
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A genetically encoded L-rhamnose biosensor for monitoring marine polysaccharide depolymerization
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Rational Design of a Biocatalyst Based on Immobilized CALB onto Nanostructured SiO2
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Establishing Modular Cell‐Free Expression System for the Biosynthesis of Bicyclomycin from a Chemically Synthesized Cyclodipeptide†
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Hosts engineering and in vitro enzymatic synthesis for the discovery of novel natural products and their derivatives
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Rapid Development of a Scalable Reduction of R-Carvone Utilizing Commercially Available Biocatalysts
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From biomass to biopolymer: strategic development of PEF for sustainable material solutions
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Engineered Alcohol Dehydrogenases-Catalyzed Enantiodivergent Atroposelective Synthesis of Axially Chiral Biaryl Phenols via Dynamic Kinetic Resolution
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Effects of terminal modification on the catalytic efficiency and thermostability of Brucella melitensis 7α-hydroxysteroid dehydrogenase
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The Transformative Power of Biocatalysis in Convergent Synthesis
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Introducing Savie: A Biodegradable Surfactant Enabling Chemo- and Biocatalysis and Related Reactions in Recyclable Water
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Co-production of 7-chloro-tryptophan and indole pyruvic acid based on an efficient FAD/FADH2 regeneration system
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The enzyme interactome concept in filamentous fungi linked to biomass valorization
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Yeast Cell Surface Engineering of a Nicotinamide Riboside Kinase for the Production of β-Nicotinamide Mononucleotide via Whole-Cell Catalysis
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Engineering a cytochrome P450 enzyme as a peroxygenase for selective hydroxylation of steroids
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Synthesis of Chiral Sulfoxides by A Cyclic Oxidation‐Reduction Multi‐Enzymatic Cascade Biocatalysis
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Accelerating overall electrochemical water splitting at the heterogeneous interface of surface crystallized Chiral Amide-bonded CoIIporphyrins
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Photobiocatalytic Cascades for Acylating N‐Heterocycles with Natural Amino Acids via the 2‐Keto Acids
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Opportunities When Chemistry Meets Biology in Catalysis and Synthesis
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Improvement of the activity and thermostability of l-threonine aldolase from Pseudomonas putida via tailoring of the active sites lining the binding pocket
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Construction of Double‐enzyme Complexes with DNA Framework Nanorulers for Improving Enzyme Cascade Catalytic Efficiency
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Insights into the Mechanisms of Sugar Acceptor Selectivity of Plant Flavonoid Apiosyltransferases
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Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole‐Cell Factory Saccharomyces Cerevisae
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Biocatalytic Hydroxylation of Progesterone by Penicillium aculeatum
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In Vivo Detection of Low Molecular Weight Platform Chemicals and Environmental Contaminants by Genetically Encoded Biosensors
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A Comprehensive Guide to Enzyme Immobilization: All You Need to Know
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Biocatalytic and Regioselective Exchange of 2‐O‐Benzoyl for 2‐O‐(m‐Substituted)Benzoyl Groups to Make Precursors of Next‐Generation Paclitaxel Drugs
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Biosensor and chemo-enzymatic one-pot cascade applications to detect and transform PET-derived terephthalic acid in living cells
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Two anti‐Prelog NAD‐Dependent Alcohol Dehydrogenases with Broad Substrate Scope and Excellent Enantioselectivity
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Mechanism-guided tunnel engineering to increase the efficiency of a flavin-dependent halogenase
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Data-driven enzyme engineering to identify function-enhancing enzymes
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Protein Engineering, Design and Selection, 2023, 36
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Enzyme and nanozyme biosensors based on MOFs for pesticide detection
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Structure‐ and Data‐Driven Protein Engineering of Transaminases for Improving Activity and Stereoselectivity
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Angew Chem Int Ed, 2023, 62
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A Single Enzyme in Enantiocomplementary Synthesis of β‐Nitroalcohols: Bidirectional Catalysis by Hydroxynitrile Lyase
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ChemBioChem, 2024, 25
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Where Chemocatalysis Meets Biocatalysis: In Water
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Transamination-Like Reaction Catalyzed by Leucine Dehydrogenase for Efficient Co-Synthesis of α-Amino Acids and α-Keto Acids
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Noncanonical Amino Acids: Bringing New-to-Nature Functionalities to Biocatalysis
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Emerging Strategies for Asymmetric Synthesis: Combining Enzyme Promiscuity and Photo‐/Electro‐redox Catalysis
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Asian J Org Chem, 2023, 12
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Generative artificial intelligence for enzyme design: Recent advances in models and applications
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Current Opinion in Green and Sustainable Chemistry, 2025, 52, 101010
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Exploring Oxidoreductases from Extremophiles for Biosynthesis in a Non-Aqueous System
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IJMS, 2023, 24, 6396
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Enzyme Surface Residues Direct Encapsulation into Metal–Organic Frameworks for Performance Regulation
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DNA Framework–Programmed Nanoscale Enzyme Assemblies
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Microfluidic‐Assisted Evolution of a Robust NAD+‐Dependent Enzyme with Improved Isobutanol Tolerance at Elevated Temperatures
Mariko Teshima, Robert Genth, Tenuun Bayaraa, Manuel Döring, Barbara Beer, Gerhard Schenk and Volker Sieber
ChemSusChem, 2025, 18
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Stimuli-Responsive Gold Nanocages for Cancer Diagnosis and Treatment
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Pharmaceutics, 2022, 14, 1321
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Struktur‐ und Daten‐basiertes Protein Engineering von Transaminasen zur Verbesserung von Aktivität und Stereoselektivität
Yu‐Fei Ao, Shuxin Pei, Chao Xiang, Marian J. Menke, Lin Shen, Chenghai Sun, Mark Dörr, Stefan Born, Matthias Höhne and Uwe T. Bornscheuer
Angewandte Chemie, 2023, 135
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Ene‐Reductase‐Catalyzed Aromatization of Simple Cyclohexanones to Phenols
Jie Chen, Shaofang Qi, Zhiguo Wang, Liran Hu, Jialing Liu, Guixiang Huang, Yongzhen Peng, Zheng Fang, Qi Wu, Yujing Hu and Kai Guo
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Enantioselective biocatalytic desymmetrization for synthesis of enantiopure cis-3,4-disubstituted pyrrolidines
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Green Synthesis and Catalysis, 2021, 2, 324
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Effiziente enzymatische Synthese von Carbamaten in Wasser durch promiskuitive Esterasen/Acyltransferasen
Hannes Meinert, Florian Oehlschläger, Clemens Cziegler, Jan Rockstroh, Irene Marzuoli, Serena Bisagni, Michael Lalk, Thomas Bayer, Hans Iding and Uwe T. Bornscheuer
Angewandte Chemie, 2024, 136
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Unlocking enzymatic deracemization of structurally diverse allenes by designed photoenzymes
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Nat Commun, 2026, 17
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Bioreactive separation technology: A retrospective and perspective
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Chemical Engineering and Processing - Process Intensification, 2026, 224, 110787
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High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades
Maria L. Corrado, Tanja Knaus, Ulrich Schwaneberg and Francesco G. Mutti
Org. Process Res. Dev., 2022, 26, 2085
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Insertions and Deletions (Indels): A Missing Piece of the Protein Engineering Jigsaw
Charlotte M. Miton and Nobuhiko Tokuriki
Biochemistry, 2023, 62, 148
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A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
Shuke Wu and Uwe T. Bornscheuer
Engineering Microbiology, 2022, 2, 100006
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Chemoenzymatic Cascades Combining Biocatalysis and Transition Metal Catalysis for Asymmetric Synthesis
Sergio González‐Granda, Lorena Escot, Iván Lavandera and Vicente Gotor‐Fernández
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Reaktionskaskaden evolvierter Enzyme zur Synthese komplexer Moleküle
Katrin Rosenthal, Uwe T. Bornscheuer and Stephan Lütz
Angewandte Chemie, 2022, 134
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Biotransformation of essential oil composition of Zanthoxylum limonella by the fungus Pleopunctum pseudoellipsoideum provides the products with enhanced antimicrobial activities
Sarunpron Khruengsai, Teerapong Sripahco, Pavaret Sivapornnukul and Patcharee Pripdeevech
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Triplet–triplet annihilation-based photon-upconversion to broaden the wavelength spectrum for photobiocatalysis
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Sci Rep, 2022, 12
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A review on the immobilization of pepsin: A Lys-poor enzyme that is unstable at alkaline pH values
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International Journal of Biological Macromolecules, 2022, 210, 682
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Rational redesign of the loop dynamics of carbonyl reductase LfSDR1 to improve the stereoselectivity for asymmetric synthesis of bulky chiral alcohols
Xiaoping Yue, Yitong Li, Mankun Wei, Yu Duan, Lin Yang and Fen-Er Chen
International Journal of Biological Macromolecules, 2024, 274, 133345
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Engineering Escherichia coli asymmetry distribution‐based synthetic consortium for shikimate production
Qiang Ding, Zhendong Li, Liang Guo, Wei Song, Jing Wu, Xiulai Chen, Liming Liu and Cong Gao
Biotech & Bioengineering, 2022, 119, 3230
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Strukturaufklärung einer metagenomischen Urethanase und Verbesserung des Hydrolyseprofils durch Protein Engineering
Thomas Bayer, Gottfried J. Palm, Leona Berndt, Hannes Meinert, Yannick Branson, Louis Schmidt, Clemens Cziegler, Ina Somvilla, Celine Zurr, Leonie G. Graf, Una Janke, Christoffel P. S. Badenhorst, Stefanie König, Mihaela Delcea, Ulrike Garscha, Ren Wei, Michael Lammers and Uwe T. Bornscheuer
Angewandte Chemie, 2024, 136
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Activity Levels of Amine Transaminases Correlate with Active Site Hydrophobicity
Manideep Kollipara, Philipp Matzel, Uwe Bornscheuer and Matthias Höhne
Chemie Ingenieur Technik, 2022, 94, 1836
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Recent advances in biological synthesis of food additive succinate
Qiang Ding, Mengqi Ji, Buhan Yao, Kangliang Sheng and Yongzhong Wang
Critical Reviews in Biotechnology, 2025, 45, 1478
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Advances and prospects on production of lactulose and epilactose by cellobiose 2-epimerases: A review
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International Journal of Biological Macromolecules, 2025, 305, 141283
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Mapping the field of aroma ester biosynthesis: A review and bibliometric analysis
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Process Biochemistry, 2024, 146, 587
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Highlights of the Recent Patent Literature─Focus on Biocatalysis Innovation
David L. Hughes
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Controlled Modification of Axial Coordination of Single‐Atom Nanozymes for Biomedical Applications
Xuejing Wang, Dongyang Li and Yunteng Qu
ChemBioChem, 2026, 27
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Fusion of enzymatic proteins: Enhancing biological activities and facilitating biological modifications
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Radical Termination via β-Scission Enables Photoenzymatic Allylic Alkylation Using “Ene”-Reductases
Netgie Laguerre, Paul S. Riehl, Daniel G. Oblinsky, Megan A. Emmanuel, Michael J. Black, Gregory D. Scholes and Todd K. Hyster
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Green “one-pot” fluorescent bis-indolizine synthesis with whole-cell plant biocatalysis
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Green Processing and Synthesis, 2023, 12
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Update: Enzymatische Synthese für industrielle Anwendungen
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius and Uwe T. Bornscheuer
Angewandte Chemie, 2025, 137
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Base metal chemistry and catalysis
Marissa L. Clapson, Connor S. Durfy, Devon Facchinato and Marcus W. Drover
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Directed Evolution and Immobilization of Lactobacillus brevis Alcohol Dehydrogenase for Chemo‐Enzymatic Synthesis of Rivastigmine
Guorong Su, Lu Ran, Chang Liu, Zhaoyang Qin, Huailong Teng and Shuke Wu
Chemistry A European J, 2024, 30
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An Intramolecular Radical C–N Coupling by N-Iodosuccinimide
Shyamal Kanti Bera, Rosalin Bhanja, Chandan Chittapriya Sahu and Prasenjit Mal
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Ene‐Reductase‐Catalyzed Aromatization of Simple Cyclohexanones to Phenols
Jie Chen, Shaofang Qi, Zhiguo Wang, Liran Hu, Jialing Liu, Guixiang Huang, Yongzhen Peng, Zheng Fang, Qi Wu, Yujing Hu and Kai Guo
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A Multicatalytic Cascade for the Stereoselective Synthesis of 1,4-Chiral Nitro Alcohols
Christian Ascaso-Alegre, Álvaro Linacero-Gracia, Patricia Ferreira, Raquel P. Herrera and Juan Mangas-Sánchez
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Continuous Flow Biocatalytic Reductive Amination by Co‐Entrapping Dehydrogenases with Agarose Gel in a 3D‐Printed Mould Reactor
Federico Croci, Jan Vilím, Theodora Adamopoulou, Vasilis Tseliou, Peter J. Schoenmakers, Tanja Knaus and Francesco G. Mutti
ChemBioChem, 2022, 23
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L-proline-based deep eutectic solvents as green and enantioselective organocatalyst/media for aldol reaction
Stephany Zárate-Roldán, María J. Trujillo-Rodríguez, M. Concepción Gimeno and Raquel P. Herrera
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Microbial Spore-Based Biocatalysts: Properties, Applications and New Trends
Brana Pantelic, Nikola Radivojevic, Ivana Aleksic, Jelena Simic and Jasmina Nikodinovic-Runic
Catalysts, 2025, 15, 894
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Production of Biobased Ethylbenzene by Cascade Biocatalysis with an Engineered Photodecarboxylase
Zhaoyang Qin, Yi Zhou, Zhi Li, Matthias Höhne, Uwe T. Bornscheuer and Shuke Wu
Angew Chem Int Ed, 2024, 63
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Efficient Enzymatic Synthesis of Carbamates in Water Using Promiscuous Esterases/Acyltransferases
Hannes Meinert, Florian Oehlschläger, Clemens Cziegler, Jan Rockstroh, Irene Marzuoli, Serena Bisagni, Michael Lalk, Thomas Bayer, Hans Iding and Uwe T. Bornscheuer
Angew Chem Int Ed, 2024, 63
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Enzyme Grafting with a Cofactor-Decorated Metal-Organic Capsule for Solar-to-Chemical Conversion
Jianwei Wei, Liang Zhao, Yu Zhang, Gang Han, Cheng He, Chong Wang and Chunying Duan
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Deep Learning-Based Self-Adaptive Evolution of Enzymes
Shuiqin Jiang and Dong Yi
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Enzyme Immobilization on a Delignified Bamboo Scaffold as a Green Hierarchical Bioreactor
Yihua Ren, Libo Zhang, Tao Sun, Yingwu Yin and Qian Wang
ACS Sustainable Chem. Eng., 2022, 10, 6244
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Industrial applicability of enzymatic and whole-cell processes for the utilization of C1 building blocks
Giovanni Davide Barone, Ina Somvilla, Hannah Pia Franziska Meier, Anna Christina R. Ngo, Thomas Bayer, Fabio Parmeggiani, Viktoria Rehbein, Johann A. Hlina, Pablo Domínguez de María, Uwe T. Bornscheuer, Dirk Tischler and Sandy Schmidt
Nat Commun, 2025, 16
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Applications of cytochrome P450 monooxygenases in the biosynthesis of active pharmaceutical ingredients
Yuben Qiao, Xiaodong Zhang, Qianqian Xu, Ikuro Abe and Aitao Li
Green Synthesis and Catalysis, 2025
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The Biocatalysis in Cancer Therapy
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ACS Catal., 2023, 13, 7730
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Engineering substrate specificity of quinone-dependent dehydrogenases for efficient oxidation of deoxynivalenol to 3-keto-deoxynivalenol
Bin Ma, Jiafeng Niu, Hao Zhu, Huibing Chi, Zhaoxin Lu, Fengxia Lu and Ping Zhu
International Journal of Biological Macromolecules, 2024, 264, 130484
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Cascades of Evolved Enzymes for the Synthesis of Complex Molecules
Katrin Rosenthal, Uwe T. Bornscheuer and Stephan Lütz
Angew Chem Int Ed, 2022, 61
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Identification of four ene reductases and their preliminary exploration in the asymmetric synthesis of (R)-dihydrocarvone and (R)-profen derivatives
Qinghua Shi, Yutian Jia, Huibin Wang, Shang Li, Hengyu Li, Jiyang Guo, Tong Dou, Bin Qin and Song You
Enzyme and Microbial Technology, 2021, 150, 109880
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Stereoselective Synthesis of Azacycles Induced by Group 8–11 Late Transition Metals
Árpád Molnár
Eur J Org Chem, 2021, 2021, 6748
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Upstream processes of citrus fruit waste biorefinery for complete valorization
In Jung Kim, Deokyeol Jeong and Soo Rin Kim
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Biocatalytic Synthesis of Corticosteroid Derivatives by Toad-Derived Steroid C21-Hydroxylase
Meiling Duan, Xueqing Zhong, Jiaxu Qin, Guo-Qiang Lin, Qing-Li He and Qunfei Zhao
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