Continuous synthesis of ruthenium nanoparticles with tuneable sizes using ruthenium nitrosyl nitrate precursor

Joseph El-Kadi, Eugenio Fenoaltea Pieche, Seung Woo Ko and Laura Torrente-Murciano

React. Chem. Eng., 2024, 9, 1145
DOI: 10.1039/D3RE00585B

Synthesis of highly uniform and composition-controlled gold–palladium supported nanoparticles in continuous flow

Stefano Cattaneo, Sultan Althahban, Simon J. Freakley, Meenakshisundaram Sankar, Thomas Davies, Qian He, Nikolaos Dimitratos, Christopher J. Kiely and Graham J. Hutchings

Nanoscale, 2019, 11, 8247
DOI: 10.1039/C8NR09917K

Challenges and opportunities for SERS in the infrared: materials and methods

Chiara Deriu, Shaila Thakur, Olimpia Tammaro and Laura Fabris

Nanoscale Adv., 2023, 5, 2132
DOI: 10.1039/D2NA00930G

Continuous synthesis of tuneable sized silver nanoparticles via a tandem seed-mediated method in coiled flow inverter reactors

Ke-Jun Wu and Laura Torrente-Murciano

React. Chem. Eng., 2018, 3, 267
DOI: 10.1039/C7RE00194K

Intensification of silver nanoparticle synthesis through continuous flow split and recombine microreactors

Amritendu Bhuson Ghosh, Rakesh Kumar and Arnab Atta

React. Chem. Eng., 2024, 9, 1707
DOI: 10.1039/D4RE00025K

Preparation of highly active phosphated TiO2catalystsviacontinuous sol–gel synthesis in a microreactor

O. Martin, N. Bolzli, B. Puértolas, J. Pérez-Ramírez and P. Riedlberger

Catal. Sci. Technol., 2019, 9, 4744
DOI: 10.1039/C8CY02574F

Continuous manufacturing of silver nanoparticles between 5 and 80 nm with rapid online optical size and shape evaluation

Bruno Pinho and Laura Torrente-Murciano

React. Chem. Eng., 2020, 5, 342
DOI: 10.1039/C9RE00452A

Autonomous optimisation of a nanoparticle catalysed reduction reaction in continuous flow

Brendan L. Hall, Connor J. Taylor, Ricardo Labes, Alexander F. Massey, Robert Menzel, Richard A. Bourne and Thomas W. Chamberlain

Chem. Commun., 2021, 57, 4926
DOI: 10.1039/D1CC00859E

A sustainable, top-down mechanosynthesis of carbohydrate-functionalized silver nanoparticles

Andrea Pietro Reverberi, Marco Vocciante, Marco Salerno, Omar Soda and Bruno Fabiano

React. Chem. Eng., 2022, 7, 888
DOI: 10.1039/D1RE00391G

Jet-mixing reactor for the production of monodisperse silver nanoparticles using a reduced amount of capping agent

Pinaki Ranadive, Aamena Parulkar and Nicholas A. Brunelli

React. Chem. Eng., 2019, 4, 1779
DOI: 10.1039/C9RE00152B

Coiled flow inverter mediated synthesis of activated carbon fiber-supported Ni nanoparticles

Amol Pophali, Rakshit Kajala, Haider Ali, Nishith Verma and K. D. P. Nigam

React. Chem. Eng., 2022, 7, 719
DOI: 10.1039/D1RE00338K

Continuous low temperature synthesis of MAPbX3 perovskite nanocrystals in a flow reactor

Xinxing Liang, Robert W. Baker, Kejun Wu, Wentao Deng, Dominic Ferdani, Peter S. Kubiak, Frank Marken, Laura Torrente-Murciano and Petra J. Cameron

React. Chem. Eng., 2018, 3, 640
DOI: 10.1039/C8RE00098K

Green, scalable, low cost and reproducible flow synthesis of biocompatible PEG-functionalized iron oxide nanoparticles

Julien Mahin, Christoph O. Franck, Luise Fanslau, Hirak K. Patra, Michael D. Mantle, Ljiljana Fruk and Laura Torrente-Murciano

React. Chem. Eng., 2021, 6, 1961
DOI: 10.1039/D1RE00239B

Continuous flow synthesis of plasmonic magnesium nanoparticles with tunable optical properties from grignard precursors

Vladimir Lomonosov, Andrey Ten, Bruno Pinho, Zeki Semih Pehlivan, Emilie Ringe and Laura Torrente-Murciano

Nanoscale, 2025, 17, 27522
DOI: 10.1039/D5NR03384E

Continuous synthesis of hollow silver–palladium nanoparticles for catalytic applications

Ke-Jun Wu, Yunhu Gao and Laura Torrente-Murciano

Faraday Discuss., 2018, 208, 427
DOI: 10.1039/C8FD00001H

Mechanistic insights of the reduction of gold salts in the Turkevich protocol

Yunhu Gao and Laura Torrente-Murciano

Nanoscale, 2020, 12, 2740
DOI: 10.1039/C9NR08877F

Synthesis of Fe₃O₄ Magnetic Nanoparticles in a Helical Microreactor

Dan Wang, Mudassir Iqbal and Ming Qiao Zhu

KEM, 2020, 842, 174
DOI: 10.4028/www.scientific.net/KEM.842.174

Rational design of the inlet configuration of flow systems for enhanced mixing

Yunhu Gao, Di Fu Zhu, Yuan Han and Laura Torrente-Murciano

J Flow Chem, 2021, 11, 589
DOI: 10.1007/s41981-021-00184-z

Ultrasound-assisted synthesis of visible-light-driven Ag/g-C3N4 catalysts in a continuous flow reactor

Hai Zhu, Ke-Jun Wu and Chao-Hong He

Chemical Engineering Journal, 2022, 429, 132412
DOI: 10.1016/j.cej.2021.132412

Microfluidics nanoprecipitation of telmisartan nanoparticles: effect of process and formulation parameters

Preena Shrimal, Girirajsinh Jadeja and Sanjaykumar Patel

Chem. Pap., 2021, 75, 205
DOI: 10.1007/s11696-020-01289-w

Continuous Flow Methods of Fabricating Catalytically Active Metal Nanoparticles

Emily J. Roberts, Lanja R. Karadaghi, Lu Wang, Noah Malmstadt and Richard L. Brutchey

ACS Appl. Mater. Interfaces, 2019, 11, 27479
DOI: 10.1021/acsami.9b07268

Predicting the size of silver nanoparticles synthesised in flow reactors: Coupling population balance models with fluid dynamic simulations

Cintia Casado, Bruno Pinho, Javier Marugán and Laura Torrente-Murciano

Chemical Engineering Journal, 2024, 479, 147684
DOI: 10.1016/j.cej.2023.147684

Hydrodynamic assembly of two-dimensional layered double hydroxide nanostructures

Nicholas A. Jose, Hua Chun Zeng and Alexei A. Lapkin

Nat Commun, 2018, 9
DOI: 10.1038/s41467-018-07395-4

Tailoring the size of silver nanoparticles by controlling mixing in microreactors

Yunhu Gao, Bruno Pinho and Laura Torrente-Murciano

Chemical Engineering Journal, 2022, 432, 134112
DOI: 10.1016/j.cej.2021.134112

Ultrafast, Continuous and Shape-Controlled Preparation of CeO2 Nanostructures: Nanorods and Nanocubes in a Microfluidic System

Hongbao Yao, Yujun Wang, Yu Jing and Guangsheng Luo

Ind. Eng. Chem. Res., 2018, 57, 7525
DOI: 10.1021/acs.iecr.8b01298

The importance of transport phenomena on the flow synthesis of monodispersed sharp blue-emitting perovskite CsPbBr3 nanoplatelets

Kaiwen Zhang, Yunhu Gao, Bruno Pinho, Robert L.Z. Hoye, Samuel D. Stranks and Laura Torrente-Murciano

Chemical Engineering Journal, 2023, 451, 138752
DOI: 10.1016/j.cej.2022.138752

Optimisation of microfluidic synthesis of silver nanoparticles via data-driven inverse modelling

Konstantia Nathanael, Sibo Cheng, Nina M. Kovalchuk, Rossella Arcucci and Mark J.H. Simmons

Chemical Engineering Research and Design, 2025, 216, 523
DOI: 10.1016/j.cherd.2025.03.014

Continuous Synthesis of Uniformly Dispersed Mesoporous SBA-15 Supported Silver Nanoparticles in a Coiled Flow Inverter Reactor

Hai Zhu, Ke-Jun Wu and Chao-Hong He

Front. Chem., 2021, 9
DOI: 10.3389/fchem.2021.747105

Engineering advancements in microfluidic systems for enhanced mixing at low Reynolds numbers

Vamsi Vikram Gande, Prem K. R. Podupu, Bianca Berry, Nandkishor K. Nere, S. Pushpavanam and Meenesh R. Singh

Biomicrofluidics, 2024, 18
DOI: 10.1063/5.0178939

Controllable Synthesis of Silver Nanoparticles Using Piezoelectric-Actuated High-Frequency Vibration Self-Circulating Microfluidic Reactor

Guojun Liu, Fang He, Yan Li, Xinbo Li, Hong Zhao, Conghui Wang, Conghong Zhan and Chunxiu Tang

NANO, 2019, 14, 1950097
DOI: 10.1142/S1793292019500978

Integration of microfluidic systems with external fields for multiphase process intensification

Mei Yang, Yuan Gao, Yun Liu, Guangze Yang, Chun-Xia Zhao and Ke-Jun Wu

Chemical Engineering Science, 2021, 234, 116450
DOI: 10.1016/j.ces.2021.116450

Advancements of heavy metals control in the environment from detection to separation and recovery: Emerging microfluidics strategy

Xiaoyun Liu, Hongrui Xiang, Jiawei Li, Wenchao Zhang, Feiping Zhao, Qingwei Wang, Meiqing Shi, Yunyan Wang, Xu Yan and Liyuan Chai

Critical Reviews in Environmental Science and Technology, 2025, 55, 1025
DOI: 10.1080/10643389.2025.2483534

Microfluidic-assisted synthesis of uniform polymer-stabilized silver colloids

Carin C.S. Batista, Alessandro Jäger, Brunno L. Albuquerque, Ewa Pavlova, Petr Stepánek and Fernando C. Giacomelli

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 618, 126438
DOI: 10.1016/j.colsurfa.2021.126438

Recent progress on the manufacturing of nanoparticles in multi-phase and single-phase flow reactors

Yunhu Gao, Bruno Pinho and Laura Torrente-Murciano

Current Opinion in Chemical Engineering, 2020, 29, 26
DOI: 10.1016/j.coche.2020.03.008

Size-tuned silver nanoparticles by a non-gassing electro-osmotic pump-driven microfluidic device

Vidhiben Dave, Sooraj Sreenath, Gopala Ram Bhadu, Nitin G. Borle, Govind Sethia and Rajaram K. Nagarale

Journal of the Indian Chemical Society, 2025, 102, 101641
DOI: 10.1016/j.jics.2025.101641

Synthesis of Functional Nanoparticles Using a Microreactor

Satoshi Watanabe and Minoru T. Miyahara

KONA, 2025, 42, 156
DOI: 10.14356/kona.2025003

Photodynamic and Antibacterial Assessment of Gold Nanoparticles Mediated by Gold (III) Chloride Trihydrate and Sodium Citrate under Alkaline Conditions

Chien-Wei Cheng, Shwu-Yuan Lee, Tang-Yu Chen, Ching-Chuan Chen, Hsien-Tsung Tsai, Hsuan-Han Huang, Jeu-Ming P. Yuann and Ji-Yuan Liang

Materials, 2024, 17, 3157
DOI: 10.3390/ma17133157

Importance of Monitoring the Synthesis of Light‐Interacting Nanoparticles – A Review on In Situ, Ex Situ, and Online Time‐Resolved Studies

Bruno Pinho, Kaiwen Zhang, Robert L. Z. Hoye and Laura Torrente‐Murciano

Advanced Optical Materials, 2022, 10
DOI: 10.1002/adom.202200524

Enhancing mixing efficiency in curved channels: A 3D study of bi-phasic Dean-Taylor flow with high spatial and temporal resolution

Bruno Pinho, Lindsay M. Williams, Julien Mahin, Yunhu Gao and Laura Torrente-Murciano

Chemical Engineering Journal, 2023, 471, 144342
DOI: 10.1016/j.cej.2023.144342

Silver nanoparticles synthesis in microfluidic and well-mixed reactors: A combined experimental and PBM-CFD study

Paula Pico, Konstantia Nathanael, Alessio D. Lavino, Nina M. Kovalchuk, Mark J.H. Simmons and Omar K. Matar

Chemical Engineering Journal, 2023, 474, 145692
DOI: 10.1016/j.cej.2023.145692

A low-dissipative and accurate method of simulating the unsteady mixing process

Yunhu Gao, Zhongnan Wang and Zhihong Xu

Chemical Engineering Journal, 2023, 460, 141760
DOI: 10.1016/j.cej.2023.141760

Development of a predictive response surface model for size of silver nanoparticles synthesized in a T-junction microfluidic device

Konstantia Nathanael, Federico Galvanin, Nina M. Kovalchuk and Mark J.H. Simmons

Chemical Engineering Science, 2023, 279, 118907
DOI: 10.1016/j.ces.2023.118907

Microfluidic Technology Based Synthesis of Inorganic Nano-biomaterials: Principles and Progress

Ruizhi TIAN, Zhengyi LAN, Jie YIN, Nanjing HAO, Hangrong CHEN and Ming MA

Journal of Inorganic Materials, 2025, 40, 337
DOI: 10.15541/jim20240431

One-Step Synthesis of Ultrasmall Nanoparticles in Glycerol as a Promising Green Solvent at Room Temperature Using Omega-Shaped Microfluidic Micromixers

Robab Jahangir, Iqra Munir and Gurkan Yesiloz

Anal. Chem., 2023, 95, 17177
DOI: 10.1021/acs.analchem.3c01697

Comparison of Microfluidic Synthesis of Silver Nanoparticles in Flow and Drop Reactors at Low Dean Numbers

Konstantia Nathanael, Nina M. Kovalchuk and Mark J. H. Simmons

Micromachines, 2025, 16, 75
DOI: 10.3390/mi16010075

Tuning the structural and optical properties of SnO2 nanocrystals through flow conditions in a continuous flow microreactor

Muthaimanoj Periyasamy, Sumit Kumar Saha, Vasanth Balamurugan, Utsav Sengupta, Sumanta Sain, Chandrasekar Pichandi, M. Sudharsan Natteri and Arik Kar

Journal of Industrial and Engineering Chemistry, 2025, 151, 264
DOI: 10.1016/j.jiec.2025.03.052

Microfluidic synthesis of ultrasmall Co nanoparticles over reduced graphene oxide and their catalytic properties

Mei Yang, Lamei Luo and Guangwen Chen

AIChE Journal, 2020, 66
DOI: 10.1002/aic.16950

Parametric effect of continuous synthesis of metal nanoparticles within microchannels and application: A review study

Gaurav Sharma, Susmita Das, Praveen Kumar and Urska Lavrencic Stangar

Chemical Engineering Research and Design, 2024, 209, 142
DOI: 10.1016/j.cherd.2024.07.058

Synthesis of uniform spherical silver powder without dispersants in a confined impinging-jet reactor

Zhengbin Pan, Wei Dang, Yiting Xiao, Haotong Xin and Bo Kong

Chemical Engineering Research and Design, 2024, 210, 531
DOI: 10.1016/j.cherd.2024.09.019

Redefining Quantum Dot Synthesis with Additive-Manufactured Microfluidics—A Review

Faisal bin Nasser Sarbaland, Masashi Kobayashi, Daiki Tanaka, Risa Fujita and Masahiro Furuya

J, 2025, 8, 18
DOI: 10.3390/j8020018

A low-cost optofluidic threaded microreactor (OTM) for water treatment

Amparo Fernández-Pérez and Gregorio Marbán

Journal of Environmental Chemical Engineering, 2025, 13, 117436
DOI: 10.1016/j.jece.2025.117436

Continuous synthesis of boron-doped carbon nitride supported silver nanoparticles in an ultrasound-assisted coiled flow inverter microreactor

Yu-tian Tao, Ke-Jun Wu and Chao-Hong He

J Flow Chem, 2024, 14, 177
DOI: 10.1007/s41981-023-00300-1

High-Yield Synthesis of ZIF-8 Nanoparticles Using Stoichiometric Reactants in a Jet-Mixing Reactor

Aamena Parulkar and Nicholas A. Brunelli

Ind. Eng. Chem. Res., 2017, 56, 10384
DOI: 10.1021/acs.iecr.7b02849

Dielectric barrier discharge plasma synthesis of Ag/γ-Al2O3 catalysts for catalytic oxidation of CO

Yunming TAO, Yuebing XU, Kuan CHANG, Meiling CHEN, Sergey A STAROSTIN, Hujun XU and Liangliang LIN

Plasma Sci. Technol., 2023, 25, 085504
DOI: 10.1088/2058-6272/acc14c

Intensified tailoring of ZnO particles in a continuous flow reactor via hydrothermal synthesis

Fernando Delgado-Licona, Enrique A. López-Guajardo, Julio González-García, Krishna D.P. Nigam and Alejandro Montesinos-Castellanos

Chemical Engineering Journal, 2020, 396, 125281
DOI: 10.1016/j.cej.2020.125281

Dial‐A‐Particle: Precise Manufacturing of Plasmonic Nanoparticles Based on Early Growth Information—Redefining Automation for Slow Material Synthesis

Bruno Pinho and Laura Torrente‐Murciano

Advanced Energy Materials, 2021, 11
DOI: 10.1002/aenm.202100918

Induced-charge electroosmosis for rapid mixing of reactive precipitation systems to obtain small and uniform particles

Dishika Gupta, Baggie W. Nyande, Kiran Mathew Thomas, Fei Li, Andrew T.C. Mak and Richard Lakerveld

Chemical Engineering Research and Design, 2023, 190, 715
DOI: 10.1016/j.cherd.2022.12.051

Size Control in the Colloidal Synthesis of Plasmonic Magnesium Nanoparticles

Elizabeth R. Hopper, Thomas M. R. Wayman, Jérémie Asselin, Bruno Pinho, Christina Boukouvala, Laura Torrente-Murciano and Emilie Ringe

J. Phys. Chem. C, 2022, 126, 563
DOI: 10.1021/acs.jpcc.1c07544

Transport and Kinetic Effects on the Morphology of Silver Nanoparticles in a Millifluidic System

Krishna V Kinhal, Nirav Bhatt and Pushpavanam Subramaniam

Ind. Eng. Chem. Res., 2019, 58, 5820
DOI: 10.1021/acs.iecr.8b04156

Continuous synthesis of monodisperse iron@iron oxide core@shell nanoparticles

Julien Mahin and Laura Torrente-Murciano

Chemical Engineering Journal, 2020, 396, 125299
DOI: 10.1016/j.cej.2020.125299

Continuous Flow Synthesis of Copper Oxide Nanoparticles Enabling Rapid Screening of Synthesis‐Structure‐Property Relationships

Matt Jellicoe, Yibo Yang, William Stokes, Matthew Simmons, Lina Yang, Stephanie Foster, Zabeada Aslam, Jennifer Cohen, Ashi Rashid, Andrew L. Nelson, Nikil Kapur, Rik Drummond‐Brydson and Thomas W. Chamberlain

Small, 2025, 21
DOI: 10.1002/smll.202403529

Overview of the Application of Flow Microreactors in the Synthesis of Silver Nanomaterials

Xiaoai He, Aijuan Lu, Jin Cheng, Junfang Chen, Qianhui Song, Wenfang Liu and Chuanpin Chen

NANO, 2017, 12, 1730002
DOI: 10.1142/S179329201730002X

Continuous Production of Monodisperse Silver Nanoparticles Suitable for Catalysis in a Droplet-Based Microreactor System

Xintong Huang, Shunkai Xia, Seoyeon Lee, Yongqi Jia, Zhuo Chen and Jianhong Xu

ACS Appl. Nano Mater., 2023, 6, 8574
DOI: 10.1021/acsanm.3c00943

Unveiling flow and mixing mechanism of a vortex microreactor and its use in preparing uniform layered oxide materials

De‐Ming Chen, Yan‐Jiang Liu, Shi‐Xiao Wei, Ting‐Liang Xie and Shuang‐Feng Yin

AIChE Journal, 2026, 72
DOI: 10.1002/aic.70345

Mass transfer of chemical absorption of CO2 in a serpentine minichannel

Zifan Pang, Shaokun Jiang, Chunying Zhu, Youguang Ma and Taotao Fu

Chemical Engineering Journal, 2021, 414, 128791
DOI: 10.1016/j.cej.2021.128791

Synthesis of nanoparticles in a continuous flow antifouling reactor employing an internal SLIPS coating

Mabel Cornwell, Sayan Pal, Georgios Gkogkos, Ivan P. Parkin and Asterios Gavriilidis

Chemical Engineering Journal, 2025, 514, 162836
DOI: 10.1016/j.cej.2025.162836

Continuous Synthesis and Separation of Silver Nanoparticles Using an Aqueous Two-Phase System

Vamsi Vikram Gande, Rangasamy Savitha and S. Pushpavanam

Ind. Eng. Chem. Res., 2023, 62, 12904
DOI: 10.1021/acs.iecr.3c01140

Extremely Monodispersed Micrometer-Scale Spherical Particle Synthesis of Ag Inside a Microdroplet Vaporizing in Plasma

Kaishu Nitta, Takeru Hato, Hitoshi Muneoka, Yoshiki Shimizu, Kazuo Terashima and Tsuyohito Ito

ACS Omega, 2024, 9, 14310
DOI: 10.1021/acsomega.3c10215

Assessing Sodium Amide Reagents for Ester Amidations in Deep Eutectic Solvents in Continuous Flow

Andrew W. J. Platten, Bruno Pinho, Laura Torrente-Murciano and Eva Hevia

ACS Sustainable Chem. Eng., 2025, 13, 19351
DOI: 10.1021/acssuschemeng.5c08775

Pushing nanomaterials up to the kilogram scale – An accelerated approach for synthesizing antimicrobial ZnO with high shear reactors, machine learning and high-throughput analysis

Nicholas A. Jose, Mikhail Kovalev, Eric Bradford, Artur M. Schweidtmann, Hua Chun Zeng and Alexei A. Lapkin

Chemical Engineering Journal, 2021, 426, 131345
DOI: 10.1016/j.cej.2021.131345

A Sustainable Process for Continuous Synthesis and Separation of Silver Nanoparticles Using a Biocompatible Aqueous Two-Phase System

Vamsi Vikram Gande, R Savitha and Pushpavanam Subramanium

SSRN Journal, 2022
DOI: 10.2139/ssrn.4168565