Automating and improving GHG emissions calculation in pharma/fine chemicals synthesis R&D: GreenSpeed as a digital tool to navigate complex value chains

Alexander Dauth, Benjamin Kühne, Helmut Hänsel, Sara Wirsing, Kerstin Hell, Heinrich Becker, Isabelle Georg, Andreas Bathe and Bertram Cezanne

RSC Sustainability, 2026
DOI: 10.1039/D5SU00636H

From qualitative analysis to quantitative insights: a systematic review of early phase sustainability assessments of chemical processes

Katharina Waniek, C. Oliver Kappe and Rupert J. Baumgartner

Green Chem., 2025, 27, 10944
DOI: 10.1039/D5GC02565F

Towards greener-by-design fine chemicals. Part 1: synthetic frontiers

Theodore A. Gazis, Jonas Wuyts, Areti Moutsiou, Giulio Volpin, Mark J. Ford, Rodolfo I. Teixeira, Katherine M. P. Wheelhouse, Philipp Natho, Polona Žnidaršič-Plazl, Sonja Jost, Renzo Luisi, Brahim Benyahia, Bert U. W. Maes and Gianvito Vilé

Chem. Soc. Rev., 2026, 55, 619
DOI: 10.1039/D5CS00929D

The impact of earth-abundant metals as a replacement for Pd in cross coupling reactions

Michael U. Luescher, Fabrice Gallou and Bruce H. Lipshutz

Chem. Sci., 2024, 15, 9016
DOI: 10.1039/D4SC00482E

A combined microwave/continuous flow approach for the iodination of anilines and consecutive Mizoroki–Heck cross-coupling

Matteo Bartalucci, Filippo Bocerani, Francesco Ferlin, Luciano Lattuada, Fulvio Uggeri and Luigi Vaccaro

Green Chem., 2026, 28, 5701
DOI: 10.1039/D5GC06815K

Graphitic carbon nitride/nickel dual catalysis for decarboxylative synthesis of unsymmetrical ketones from keto acids

Michael T. Findlay, Florian Lukas, Francesca Rizzo, Junsong Liu, Benjamin Martin, Simon Allmendinger, Markus Furegati, Pablo Gabriel and Timothy Noël

Green Chem., 2025, 27, 14589
DOI: 10.1039/D5GC03641K

Graphitic Carbon Nitride as a Photocatalyst for Decarboxylative C(sp2)−C(sp3) Couplings via Nickel Catalysis

Florian Lukas, Michael T. Findlay, Méritxell Fillols, Johanna Templ, Elia Savino, Benjamin Martin, Simon Allmendinger, Markus Furegati and Timothy Noël

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202405902

Sustainable production of chemicals by algorithm-assisted (bio)synthesis

Bartosz A. Grzybowski, Anna Żądło-Dobrowolska, Natalia Onishchenko and Eric S. Larsen

Nat Rev Bioeng, 2025, 3, 791
DOI: 10.1038/s44222-025-00312-7

Chemical Process Development in the Pharmaceutical Industry in Europe—Insights and Perspectives from Industry Scientists

Joachim Krueger, André P. Dieskau, Jorma Hassfeld, Joerg Gries, Oliver Block, Hilmar Weinmann, Daniel Kaufmann, Stefan Hildbrand, Volker Kraft, Robert Moeckel, Juan R. Dehli, Ulrich Scholz and Carl Friedrich Nising

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202420719

Integrated Life Cycle Assessment Guides Sustainability in Synthesis: Antiviral Letermovir as a Case Study

Sander Folkerts, Maximilian G. Hoepfner, Gonzalo Guillén-Gosálbez, Javier Pérez-Ramírez and Erick M. Carreira

J. Am. Chem. Soc., 2025, 147, 40944
DOI: 10.1021/jacs.5c14470

Chemical Process Development in the Pharmaceutical Industry in Europe—Insights and Perspectives from Industry Scientists

Joachim Krueger, André P. Dieskau, Jorma Hassfeld, Joerg Gries, Oliver Block, Hilmar Weinmann, Daniel Kaufmann, Stefan Hildbrand, Volker Kraft, Robert Moeckel, Juan R. Dehli, Ulrich Scholz and Carl Friedrich Nising

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202420719

GreenScore: A User-Friendly Tool for Assessing the Sustainability of Chemical Processes

Frédéric Pin, Julien Picard and Sylvie Dhulut

Org. Process Res. Dev., 2025, 29, 1715
DOI: 10.1021/acs.oprd.5c00047

Graphitisches Kohlenstoffnitrid als Photokatalysator für die decarboxylative C(sp2)−C(sp3) Kupplung mittels Nickelkatalyse

Florian Lukas, Michael T. Findlay, Méritxell Fillols, Johanna Templ, Elia Savino, Benjamin Martin, Simon Allmendinger, Markus Furegati and Timothy Noël

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202405902