Bifidobacterium lactis BL-99 protects mice with osteoporosis caused by colitis via gut inflammation and gut microbiota regulation

Hui Lan, Wei-Hsien Liu, Hanying Zheng, Haotian Feng, Wen Zhao, Wei-Lian Hung and Hongwei Li

Food Funct., 2022, 13, 1482
DOI: 10.1039/D1FO02218K

Modification of Ganoderma lucidum spore shells into probiotic carriers: selective loading and colonic delivery of Lacticaseibacillus rhamnosus and effective therapy of inflammatory bowel disease

Ning Liao, Juan Wang, Guanwen Liu, Yinghui Li, Fengqin Xu, Keyi Xu, Dingyu Shi, Dongyan Shao, Chunmei Jiang and Junling Shi

Food Funct., 2025, 16, 908
DOI: 10.1039/D4FO04523H

Preventive effects of sheep milk on DSS-induced colitis in mice: modulation of gut microbiota and inflammatory responses

Naseer Ahmad, Zhongshi Zhu, Tingting Chu, Liu Jiaxin, Li Danni, Jiang Yue, Lei Zhang, Hao Yuan and Yuxuan Song

Food Funct., 2025, 16, 8444
DOI: 10.1039/D5FO02200B

Core fucosylation of maternal milk N-glycans imparts early-life immune tolerance through gut microbiota-dependent regulation in RORγt+ Treg cells

Yuyuan Li, Xixi Ning, Zihui Zhao, Xi He, Qidi Xue, Manlin Zhou, Wenzhe Li and Ming Li

Food Funct., 2024, 15, 4140
DOI: 10.1039/D4FO00230J

Lactobacillus rhamnosus LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway

Wen Liao, Xinyi Zhang, Chunjian Jia, Wenjing Chen, Yujie Cai, Hongyan Zhang, Jing Wei and Tingtao Chen

Food Funct., 2025, 16, 475
DOI: 10.1039/D4FO03966A

Prevention of Ulcerative Colitis in Mice by Sweet Tea (Lithocarpus litseifolius) via the Regulation of Gut Microbiota and Butyric-Acid-Mediated Anti-Inflammatory Signaling

Xiao-Qin He, Dan Liu, Hong-Yan Liu, Ding-Tao Wu, Hua-Bin Li, Xin-Shang Zhang and Ren-You Gan

Nutrients, 2022, 14, 2208
DOI: 10.3390/nu14112208

Protective Effects of Companilactobacillus crustorum MN047 against Dextran Sulfate Sodium-Induced Ulcerative Colitis: A Fecal Microbiota Transplantation Study

Tao Wang, Caihong Shi, Shuxuan Wang, Yu Zhang, Shuang Wang, Mohamedelfaieh Ismael, Jing Zhang, Xin Wang and Xin Lü

J. Agric. Food Chem., 2022, 70, 1547
DOI: 10.1021/acs.jafc.1c07316

Rosa Roxburghii Tratt Fruit Extract Prevents Dss-Induced Ulcerative Colitis in Mice by Modulating the Gut Microbiota and the IL-17 Signaling Pathway

Xingjie Li, Yihan Ling, Xiaoyi Huang, Ting Zhou, Shouxun Wu, Shuwen Zhang, Heting Zhou, Yuhong Kang, Liqun Wang, Xiaomeng Wang and Wenya Yin

Nutrients, 2023, 15, 4560
DOI: 10.3390/nu15214560

Breast-Milk Lactobacillus Gasseri FN136 Alleviates DSS-Induced Ulcerative Colitis Through Microbiota-Independent Metabolite–Host Interactions

Qingcui Li, Wenhao Wang, Fan Zhou, Xin Geng, Ce Qi, Chengwen Li and Jin Sun

Probiotics & Antimicro. Prot., 2025
DOI: 10.1007/s12602-025-10858-y

Lacticaseibacillus rhamnosus LRa05 alleviates cyclophosphamide‐induced immunosuppression and intestinal microbiota disorder in mice

Mingming Zhu, Lvzhu Yang, Sufen Kong, Yuyuan Bai and Bin Zhao

Journal of Food Science, 2024, 89, 10003
DOI: 10.1111/1750-3841.17538

Exploiting lactic acid bacteria for inflammatory bowel disease: A recent update

Yang Chen, He Gao, Jianxin Zhao, R. Paul Ross, Catherine Stanton, Hao Zhang, Wei Chen and Bo Yang

Trends in Food Science & Technology, 2023, 138, 126
DOI: 10.1016/j.tifs.2023.06.007

Exploring PLGA-OH-CATH30 Microspheres for Oral Therapy of Escherichia coli-Induced Enteritis

Xiaoqian Jiao, Bin Liu, Xufeng Dong, Shubai Wang, Xiulei Cai, Hongliang Zhang and Zhihua Qin

Biomolecules, 2024, 14, 86
DOI: 10.3390/biom14010086

The role of gut microbiota and plasma metabolites in ulcerative colitis: Insights from Mendelian randomization analysis

XuWen Zheng, JinNuo Fan, JinNan Yin and Ying Chu

Medicine, 2025, 104, e41710
DOI: 10.1097/MD.0000000000041710

Exopolysaccharide from Bifidobacterium breve alleviate dextran sulfate sodium-induced colitis in mice via inhibiting oxidative stress and regulating intestinal flora

Meng-Meng Niu, Huan-Xin Guo, Jun-Wu Cai, Bo-Fan Duan, Yu-Han Chen and Xiang-Chen Meng

Food Bioscience, 2023, 56, 103020
DOI: 10.1016/j.fbio.2023.103020

Probiotics for the treatment of ulcerative colitis: a review of experimental research from 2018 to 2022

Cuilan Huang, Wujuan Hao, Xuyang Wang, Renmin Zhou and Qiong Lin

Front. Microbiol., 2023, 14
DOI: 10.3389/fmicb.2023.1211271

The role of a novel antibacterial substance,cyclic opine-producing Lacticaseibacillus rhamnosus LS8 in ameliorating ulcerative colitis:a fecal microbiota transplantation study

Tao Wang, Shuang Wang, Shuchen Dong, Ruiling Wang, Shuxuan Wang, Jie Yang, Xin Wang and Xin Lü

Food Science and Human Wellness, 2024, 13, 778
DOI: 10.26599/FSHW.2022.9250066

Dracocephalum moldavica L. extract alleviates experimental colitis in rats by modulating gut microbiome and inflammatory pathways

Suhe Gang, Wenhui Bai, Hui Yu, Gula A and Zhanli Wang

Mol Med Rep, 2023, 28
DOI: 10.3892/mmr.2023.13115

Improvement of inflammatory bowel disease by lactic acid bacteria-derived metabolites: a review

Weiling Guo, Bingyong Mao, Xin Tang, Qiuxiang Zhang, Jianxin Zhao, Hao Zhang, Wei Chen and Shumao Cui

Critical Reviews in Food Science and Nutrition, 2025, 65, 1261
DOI: 10.1080/10408398.2023.2291188

Lactobacillus plantarum ZJUIDS04 alleviates DSS-induced colitis via modulating gut microbiota

Chongwei Yu, Jingtianyi Liu, Zonghao Liu, Qinchao Ding, Qinchao Zhu, Nan Chen, Jinfeng Fu, Teresa G. Valencak and Daxi Ren

Journal of Functional Foods, 2023, 109, 105794
DOI: 10.1016/j.jff.2023.105794

An orally biological chemotaxis-guided hypoxia-responsive biomimetic microcapsules for visualizing multi-faceted synergistic therapy of inflammatory bowel disease

Yifei Wang, Yaning Xia, Mengyang Zhou, Yong Zhang, Jingliang Cheng and Yupeng Shi

Chemical Engineering Journal, 2025, 506, 160203
DOI: 10.1016/j.cej.2025.160203

Peach gum polysaccharide protects intestinal barrier function, reduces inflammation and oxidative stress, and alleviates pulmonary inflammation induced by Enterococcus faecium E745

Shugang Li, Guopeng Li, Dongjie Liu, Mingxin Li, Huanhuan Liu, Wenxiu Zhu, Ke Wang and Xiaomeng Ren

Journal of Functional Foods, 2024, 115, 106098
DOI: 10.1016/j.jff.2024.106098

Association between intestinal microbiome and inflammatory bowel disease: Insights from bibliometric analysis

Pengfei Xu, Tengteng Lv, Shenghui Dong, Zhihao Cui, Xinyuan Luo, Baolei Jia, Che Ok Jeon and Jie Zhang

Computational and Structural Biotechnology Journal, 2022, 20, 1716
DOI: 10.1016/j.csbj.2022.04.006

Unveiling Yiyi Fuzi Baijiang powder: Microecological and network pharmacology approach to ulcerative colitis treatment

Liang-Kun Zhang, Wen-Chao Gu and Jian Chen

World J Gastroenterol, 2025, 31
DOI: 10.3748/wjg.v31.i42.111708

The Lactobacillus gasseri G098 Strain Mitigates Symptoms of DSS-Induced Inflammatory Bowel Disease in Mice

Wei-Qin Zhang, Ke-Yu Quan, Cui-Jiao Feng, Tao Zhang, Qiu-Wen He, Lai-Yu Kwok and Yong-Fu Chen

Nutrients, 2022, 14, 3745
DOI: 10.3390/nu14183745

Sijunzi decoction alleviates inflammation and intestinal epithelial barrier damage and modulates the gut microbiota in ulcerative colitis mice

Hailun Li, Xing Pu, Yongtao Lin, Xinxin Yu, Jing Li, Lin Bo, Hongwu Wang, Yong Xu, Xiang Li and Donghui Zheng

Front. Pharmacol., 2024, 15
DOI: 10.3389/fphar.2024.1360972

Curcumin-loaded polysaccharide microparticles alleviated DSS-induced ulcerative colitis by improving intestinal microecology and regulating MAPK/NF-κB/Nrf2/NLRP3 pathways

Lu Wang, Weiyun Zheng, Qiuyue Men, Xiaomeng Ren, Shuang Song and Chunqing Ai

International Journal of Biological Macromolecules, 2024, 281, 136687
DOI: 10.1016/j.ijbiomac.2024.136687

A narrative review of the moderating effects and repercussion of exercise intervention on osteoporosis: ingenious involvement of gut microbiota and its metabolites

Yuan-Wei Zhang, Mu-Min Cao, Ying-Juan Li, Xiang-Xu Chen, Qian Yu and Yun-Feng Rui

J Transl Med, 2022, 20
DOI: 10.1186/s12967-022-03700-4

Evaluating the Therapeutic Efficacy of Lactobacillus Strains in the Management of Ulcerative Colitis: An Overview of Recent Advances

Shaghayegh Rezaei, Elnaz Ghorbani, Abdulridha Mohammed Al-Asady, Amir Avan, Saman Soleimanpour, Majid Khazaei and Seyed Mahdi Hassanian

CPD, 2025, 31, 413
DOI: 10.2174/0113816128322653240925115114

Interaction of Companilactobacillus crustorum MN047-derived bacteriocins with gut microbiota

Tao Wang, Shuxuan Wang, Shuchen Dong, Yu Zhang, Mohamedelfatieh Ismael, Shuang Wang, Caihong Shi, Jie Yang, Xin Wang and Xin Lü

Food Chemistry, 2022, 396, 133730
DOI: 10.1016/j.foodchem.2022.133730

Atractylodes macrocephala Koidz. volatile oil relieves acute ulcerative colitis via regulating gut microbiota and gut microbiota metabolism

Hao Cheng, Dandan Zhang, Jing Wu, Juan Liu, Yuzhu Tan, Wuwen Feng and Cheng Peng

Front. Immunol., 2023, 14
DOI: 10.3389/fimmu.2023.1127785

Lactobacillus delbrueckii CIDCA 133 fermented milk modulates inflammation and gut microbiota to alleviate acute colitis

Luís Cláudio Lima de Jesus, Andria dos Santos Freitas, Joyce da Cruz Ferraz Dutra, Gabriela Munis Campos, Monique Ferrary Américo, Juliana Guimarães Laguna, Evandro Gonçalves Dornelas, Rodrigo Dias de Oliveira Carvalho, Kátia Duarte Vital, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Jamil Silvano de Oliveira, Marcos Felipe Andrade de Oliveira, Ana Maria Caetano Faria, Enio Ferreira, Ramon de Oliveira Souza, Flaviano Santos Martins, Fernanda Alvarenga Lima Barroso and Vasco Azevedo

Food Research International, 2024, 186, 114322
DOI: 10.1016/j.foodres.2024.114322

Lactobacillus paracasei from koumiss ameliorates diarrhea in mice via tight junctions modulation

Shunan Ren, Aorigele Chen, Yanping Tian, Zhaoxing Bai and Chunjie Wang

Nutrition, 2022, 98, 111584
DOI: 10.1016/j.nut.2021.111584

Bacillus coagulans alleviates intestinal barrier injury induced by Klebsiella pneumoniae in rabbits by regulating the TLR4/MyD88/NF-κB signalling pathway

Jianing Wang, Ziqiang Zhang, Jiajia Wang, Lihui Shi, Shuaishuai Wang, Bingyu Niu, Xiaonuo Tian, Qiongxia Lv, Lan Wei, Mengyun Li and Yumei Liu

Veterinary Microbiology, 2025, 301, 110364
DOI: 10.1016/j.vetmic.2024.110364

Polysaccharide from Ziziphus jujuba cv. Changzao prevented colitis in mice by regulating the inflammation-gut microbiota-metabolite axis

Yina Huang, Yubin Chen, Jingyu He, Xunmei Shi, Yao He, Wu Sun, Chuanchao Wu, Kui Zhao and Di Xu

Journal of Functional Foods, 2025, 135, 107098
DOI: 10.1016/j.jff.2025.107098

A mannose-rich exopolysaccharide-1 isolated from Bifidobacterium breve mitigates ovalbumin-induced intestinal damage in mice by modulation CD4 + T cell differentiation and inhibiting NF-κB signaling pathway

Meng-Meng Niu, Yan Li, Qian Su, Si-Yuan Chen, Qiao-Hui Li, Huan-Xin Guo, Xiang-Chen Meng and Fei Liu

International Journal of Biological Macromolecules, 2024, 280, 135850
DOI: 10.1016/j.ijbiomac.2024.135850

Structural characterization of peach gum polysaccharide and its effects on the regulation of DSS-induced acute colitis

Chaoyang Wei, Li Yao, Yu Zhang, Shuyi Qiu, Xiangyong Zeng, Shiguo Chen and Xingqian Ye

International Journal of Biological Macromolecules, 2023, 225, 1224
DOI: 10.1016/j.ijbiomac.2022.11.183

Estrogenic Effect of Probiotics on Anxiety and Depression: A Narrative Review

Gilberto Uriel Rosas-Sánchez, León Jesús Germán-Ponciano, Juan Francisco Rodríguez-Landa, Herlinda Bonilla-Jaime, Ofelia Limón-Morales, Rosa Isela García-Ríos, José Luis Muñoz-Carrillo, Oscar Gutiérrez-Coronado, Paola Trinidad Villalobos-Gutiérrez and César Soria-Fregozo

IJMS, 2025, 26, 9948
DOI: 10.3390/ijms26209948

Therapeutic Effects of Camel Milk Exosomes and Their miR-148a-3p Cargo on DSS-Induced Colitis: Modulating Gut Inflammation through the SIRT1/NF-κB Pathway and Microbiota Alterations

Siriguleng Yu, Chaoqun Liu, Hongqiang Yao, Zhijun Guo, Xiaoxuan Yan, Lijun Liu, Yang Xu and Qiuyue Yu

J. Agric. Food Chem., 2026, 74, 1448
DOI: 10.1021/acs.jafc.5c11226

Emodin-8-O-β-D-glucopyranoside alleviates cholestasis by maintaining intestinal homeostasis and regulating lipids and bile acids metabolism in mice

Xiaolin Wu, Qiao Yu, Yuzhao Hou, Xuemei Zhang, Simon Sani Ocholi, Liming Wang, Ziping Yan, Jie Li and Lifeng Han

Journal of Pharmaceutical and Biomedical Analysis, 2025, 258, 116734
DOI: 10.1016/j.jpba.2025.116734

Mn2O3 NPs-induced liver injury is potentially associated with gut microbiota dysbiosis in broiler chicken

Yuanliang Li, Jiangnan Yi, Kai Liu, Xiaoqing Liu, Chamba Yangzom, Jiaqiang Pan, Mujahid Iqbal, Lianmei Hu, Zhaoxin Tang, Ying Li and Hui Zhang

Food and Chemical Toxicology, 2025, 202, 115487
DOI: 10.1016/j.fct.2025.115487

Dynamic changes of inulin utilization associated with longitudinal development of gut microbiota

Nana Chen, Yalin Liu, Siyu Wei, Xin Zong, Guilian Zhou, Zeqing Lu, Fengqin Wang, Yizhen Wang and Mingliang Jin

International Journal of Biological Macromolecules, 2023, 229, 952
DOI: 10.1016/j.ijbiomac.2022.12.318

Synergistic effects of probiotics with soy protein alleviate ulcerative colitis by repairing the intestinal barrier and regulating intestinal flora

Rentang Zhao, Bingqing Shang, Luyan Sun, Suyuan Lv, Guolong Liu, Qiu Wu and Yue Geng

Journal of Functional Foods, 2024, 122, 106514
DOI: 10.1016/j.jff.2024.106514

Probiotics with Emodin-nanobackpack restore goblet cell-dependent mucus layer integrity via colonic patches to ameliorate ulcerative colitis

Linxin Dai, Qian Wang, Lingling He, Ziyu Yuan, Fenglian Zhang, Ruifeng Luo, Lingqiang Li, Wenzhen Zhong, Yan Ye, Wen Li, Chaomei Fu, Peng Zhao, Runchun Xu, Chuan Zheng, Ruibing Wang and Fei Gao

Journal of Controlled Release, 2026, 393, 114769
DOI: 10.1016/j.jconrel.2026.114769

The Changes in Bacterial Microbiome Associated with Immune Disorder in Allergic Respiratory Disease

Juanjuan Lyu, Fangfang Kou, Xiangyu Men, Yinhui Liu, Li Tang and Shu Wen

Microorganisms, 2022, 10, 2066
DOI: 10.3390/microorganisms10102066

Ulcerative colitis: signaling pathways, therapeutic targets and interventional strategies

Jinhao Jia, Ying Liu, Dan Wang, Zhaohai Pan, Qiusheng Zheng, Jun Lu, Chao Liang and Defang Li

Sig Transduct Target Ther, 2026, 11
DOI: 10.1038/s41392-025-02345-1

Microbial Composition and Stool Short Chain Fatty Acid Levels in Fibromyalgia

Yunkyung Kim, Geun-Tae Kim and Jihun Kang

IJERPH, 2023, 20, 3183
DOI: 10.3390/ijerph20043183

Applications of Food-Associated Lactobacillaceae in Fermented Foods, Health, and Emerging Biotechnologies

Shazia Pathan, Veronika Karlegan and David Q. Shih

Fermentation, 2026, 12, 75
DOI: 10.3390/fermentation12020075

Goat Milk Exosomes Ameliorate Ulcerative Colitis in Mice through Modulation of the Intestinal Barrier, Gut Microbiota, and Metabolites

Feng Gao, Shenghui Wu, Kang Zhang, Zhiming Xu, Xin Zhang, Zhengjin Zhu and Fusheng Quan

J. Agric. Food Chem., 2024, 72, 23196
DOI: 10.1021/acs.jafc.4c03212

Therapeutic Potential of Short-Chain Fatty Acids in Gastrointestinal Diseases

Meng Tong Zhu and Jonathan Wei Jie Lee

Nutraceuticals, 2025, 5, 19
DOI: 10.3390/nutraceuticals5030019

Postbiotic Administration Ameliorates Colitis and Inflammation in Rats Possibly through Gut Microbiota Modulation

Cuijiao Feng, Chuantao Peng, Weiqin Zhang, Tao Zhang, Qiuwen He, Lai-Yu Kwok and Heping Zhang

J. Agric. Food Chem., 2024
DOI: 10.1021/acs.jafc.3c03901

Lactobacillus rhamnosus MP108 alleviates ulcerative colitis in mice by enhancing the intestinal barrier, inhibiting inflammation, and modulating gut microbiota

Huizhen Li, Yang Chen, Huiting Fang, Xinmei Guo, Xuecong Liu, Jianxin Zhao, Wei Chen and Bo Yang

Food Science and Human Wellness, 2025, 14, 9250139
DOI: 10.26599/FSHW.2024.9250139

Oral administration of octacosanol modulates the gut bacteria and protects the intestinal barrier in ulcerative colitis mice

Shu‐Ting Miao, Qian‐Shan Lu, Ying‐Jun Zhou, Ya‐Ning Chang, Tao Xu and Meng‐Yu Zhu

Journal of Food Biochemistry, 2022, 46
DOI: 10.1111/jfbc.14284

The Protective Effect of Heat-Inactivated Companilactobacillus crustorum on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice

Yujie Zhong, Tao Wang, Xin Wang and Xin Lü

Nutrients, 2023, 15, 2746
DOI: 10.3390/nu15122746

The Potential Therapeutic Role of Lactobacillaceae rhamnosus for Treatment of Inflammatory Bowel Disease

Hang Guo, Leilei Yu, Fengwei Tian, Wei Chen and Qixiao Zhai

Foods, 2023, 12, 692
DOI: 10.3390/foods12040692

The triple interactions between gut microbiota, mycobiota and host immunity

Jingpeng Yang, Hong Yang and Yanan Li

Critical Reviews in Food Science and Nutrition, 2023, 63, 11604
DOI: 10.1080/10408398.2022.2094888

Integrated Metabolomics and Gut Microbiome Analysis Reveals the Efficacy of a Phytochemical Constituent in the Management of Ulcerative Colitis

Kai Zhang, Jianbin Ji, Nana Li, Zhaorui Yin and Guanwei Fan

Molecular Nutrition Food Res, 2024, 68
DOI: 10.1002/mnfr.202200578

Gut-mammary pathway: Breast milk microbiota as a mediator of maternal gut microbiota transfer to the infant gut

Lulu Meng, Haishan Xie, Zhe Li, Kian Deng Tye, Ge Fan, Ting Huang, Hao Yan, Xiaomei Tang, Huijuan Luo and Xiaomin Xiao

Journal of Functional Foods, 2025, 124, 106620
DOI: 10.1016/j.jff.2024.106620

In vitro digestion and fecal fermentation of basidiospore-derived exopolysaccharides from Naematelia aurantialba

Tao Sun, Xiaoning Liang, Xiaoyi Xu, Linhao Wang, Wei Xiao, Yuhang Ma, Rui Wang, Yian Gu, Sha Li, Yibin Qiu, Dafeng Sun, Hong Xu and Peng Lei

International Journal of Biological Macromolecules, 2024, 261, 129756
DOI: 10.1016/j.ijbiomac.2024.129756

Eurotium cristatum-Fermented White Tea Ameliorates DSS-Induced Colitis by Multi-Scale

Huini Wu, Xiangrui Kong, Ruiyang Shan, Song Peng, Mengshi Zhao, Wenquan Yu, Changsong Chen, Xiuping Wang and Zhaolong Li

Foods, 2025, 15, 72
DOI: 10.3390/foods15010072

Akkermansia muciniphila-Nlrp3 is involved in the neuroprotection of phosphoglycerate mutase 5 deficiency in traumatic brain injury mice

Yuhua Chen, Junhui Chen, Hong Wei, Kai Gong, Jiao Meng, Tianlin Long, Jianfeng Guo, Jun Hong, Lingjian Yang, Junling Qiu, Kun Xiong, Zhanxiang Wang and Quanhua Xu

Front. Immunol., 2023, 14
DOI: 10.3389/fimmu.2023.1172710