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Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry

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J. Med. Chem., 2017, 60, 4126
DOI: 10.1021/acs.jmedchem.6b01601

Opioid Ligands Addressing Unconventional Binding Sites and More Than One Opioid Receptor Subtype

Antonios Drakopoulos, Dimitrios Moianos, Georgia‐Myrto Prifti, Grigoris Zoidis and Michael Decker

ChemMedChem, 2022, 17
DOI: 10.1002/cmdc.202200169

Structure–Activity Relationship Studies of 6α- and 6β-Indolylacetamidonaltrexamine Derivatives as Bitopic Mu Opioid Receptor Modulators and Elaboration of the “Message-Address Concept” To Comprehend Their Functional Conversion

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ACS Chem. Neurosci., 2019, 10, 1075
DOI: 10.1021/acschemneuro.8b00349

In silico identification of a biarylamine acting as agonist at human β3 adrenoceptors and exerting BRL37344-like effects on mouse metabolism

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