One-shot preparation of an inherently chiral trifunctional calix[4]arene from an easily available cone-triformylcalix[4]arene†‡
Abstract
Via selective 1,3-distal intramolecular Cannizzaro disproportionation of an easily available cone-triformylcalix[4]arene, an inherently chiral trifunctional cone-calix[4]arene derivative has been prepared. The presence of three different functional groups (–CH2OH, –CHO and –COOH) at the upper rim of the
- This article is part of the themed collection: In Celebration of Andrew D. Hamilton’s Career in Chemistry