Photoinduced reductive cyclization of 2-nitroaryl-tethered carbonyl compounds: an approach for accessing nitrogen-fused heterocycles

Abstract

In the presence of AcSH and DIPEA, a photo-induced reductive cyclization reaction of 2-nitroaryl-tethered carbonyl compounds was achieved, affording a mild method for the preparation of N-fused heterocycles including quinoline, quinoxaline, oxazine, quinazolinone, and indolone. Preliminary mechanistic studies suggested that this catalyst-free transformation was triggered by a visible-light-induced EDA complex-based SET reduction process.