Issue 12, 2018

Azidoheteroarylation of unactivated olefins through distal heteroaryl migration

Abstract

The radical-mediated azidoheteroarylation of unactivated olefins has been accomplished for the first time based on the strategy of intramolecular distal heteroaryl migration. A variety of synthetically useful heteroaryl-substituted alkyl azides are readily furnished under mild reaction conditions. The utility of the protocol is manifested by readily converting the products to piperidine, β-pipecolic acid, and triazole derivatives.

Graphical abstract: Azidoheteroarylation of unactivated olefins through distal heteroaryl migration

Supplementary files

Article information

Article type
Research Article
Submitted
20 মার্চ 2018
Accepted
27 এপ্রিল 2018
First published
28 এপ্রিল 2018

Org. Chem. Front., 2018,5, 1896-1899

Azidoheteroarylation of unactivated olefins through distal heteroaryl migration

M. Wang, Z. Wu, B. Zhang and C. Zhu, Org. Chem. Front., 2018, 5, 1896 DOI: 10.1039/C8QO00301G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements