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Abstract | Cited by

A novel pyrano[3,2-c]julolidin-2-one based fluorescent molecular rotor PYJO4 has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg2+ in live cells. The probe operates via a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb. PYJO4 coated test strips can be used to detect mercury ions in contaminated water.

Graphical abstract: Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells

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