In this study, we report a skeletal editing strategy for the modular synthesis of bipyrazole energetic compounds. This study reveals that skeletal editing via distinctive retrosynthetic logic offers new opportunities in synthesizing HEDMs.
An energetic compound with a trinitromethyl group has been achieved via a novel strategy of nitration of an ethylene bridged compound and shows excellent heat of detonation and promising properties.
Increasing the strength and number of hydrogen bonds of azoles and expanding the π–π stacking area are the key factors to improve the thermal stability, which provides a valuable way for developing energetic materials with higher energy and thermal stability.
This review depicts the full spectrum of metal pyrazaolate frameworks, highlighting their design principles, synthesis and structure, stability, and potential applications for addressing global challenges.
We have designed and synthesized three pyrazole analogs (4, 5a, 5b), pyrazole-based chalcones (6a–6d) and (8a–8h), and N-formyl/acetyl 1,3,5-trisubstituted pyrazole analogs (7a–7d), (9a–9d) via Suzuki cross-coupling as the key step.