Issue 7, 2024

In situ peptide assemblies for bacterial infection imaging and treatment

Abstract

Bacterial infections, especially antibiotic-resistant ones, remain a major threat to human health. Advances in nanotechnology have led to the development of numerous antimicrobial nanomaterials. Among them, in situ peptide assemblies, formed by biomarker-triggered self-assembly of peptide-based building blocks, have received increasing attention due to their unique merits of good spatiotemporal controllability and excellent disease accumulation and retention. In recent years, a variety of “turn on” imaging probes and activatable antibacterial agents based on in situ peptide assemblies have been developed, providing promising alternatives for the treatment and diagnosis of bacterial infections. In this review, we introduce representative design strategies for in situ peptide assemblies and highlight the bacterial infection imaging and treatment applications of these supramolecular materials. Besides, current challenges in this field are proposed.

Graphical abstract: In situ peptide assemblies for bacterial infection imaging and treatment

Article information

Article type
Review Article
Submitted
18 ربيع الثاني 1445
Accepted
01 رجب 1445
First published
04 رجب 1445

Nanoscale, 2024,16, 3211-3225

In situ peptide assemblies for bacterial infection imaging and treatment

Y. Zhou, L. Xu, X. Sun, W. Zhan and G. Liang, Nanoscale, 2024, 16, 3211 DOI: 10.1039/D3NR05557D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements