Issue 21, 2021

The liquid micro junction-surface sampling probe (LMJ-SSP); a versatile ambient mass spectrometry interface

Abstract

Ambient ionization methods have become important tools in mass spectrometry. The LMJ-SSP can significantly simplify/reduce lengthy sample preparation requirements associated with mass spectrometry analysis. Samples may be introduced through direct contact, insertion and droplet injection, enabling applications from drug discovery and surface analysis to tissue profiling and metabolic mapping. This review examines the underlying principles associated with the LMJ-SSP interface and highlights modifications of the original design that have extended its capability. We summarize different application areas that have exploited the method and describe potential future directions for the adaptable ambient ionization source.

Graphical abstract: The liquid micro junction-surface sampling probe (LMJ-SSP); a versatile ambient mass spectrometry interface

Article information

Article type
Critical Review
Submitted
14 رمضان 1442
Accepted
22 محرم 1443
First published
01 صفر 1443

Analyst, 2021,146, 6365-6378

The liquid micro junction-surface sampling probe (LMJ-SSP); a versatile ambient mass spectrometry interface

D. Simon and R. Oleschuk, Analyst, 2021, 146, 6365 DOI: 10.1039/D1AN00725D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements