A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods

Yu Mao; Jiuxing Li; Jinmao Yan; Yanli Ma; Yanling Song; Tian Tian; Xuan Liu; Zhi Zhu; Leiji Zhou; Chaoyong Yang

doi:10.1039/C7CC01360D

A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods†

Yu Mao,^a Jiuxing Li,^a Jinmao Yan,^a Yanli Ma,^a Yanling Song,^a Tian Tian,^a Xuan Liu,^a Zhi Zhu,^a Leiji Zhou

*^a and Chaoyong Yang

^a

Author affiliations

* Corresponding authors

^a MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
E-mail: ljzhou@xmu.edu.cn

Abstract

A new method based on a functional DNA crosslinked hydrogel as a target-responsive unit and gold nanorods (AuNRs) as a multicolor signal readout circuit was developed for the sensitive and visual detection of different targets. The color variation of the AuNR solution was correlated with the concentration of the target. This system can be extended to detect various targets by designing the corresponding target-responsive DNA hydrogels.

This article is part of the themed collection: Celebrating a Century of Excellency in Chemistry at Xiamen University

Chemical Communications

A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods†

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A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods

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