Issue 5, 2016

A strategy for enhanced antibacterial activity against Staphylococcus aureus by the assembly of alamethicin with a thermo-sensitive polymeric carrier

Abstract

We demonstrate here a strategy for enhanced antibacterial activity against microbial strains by the assembly of antimicrobial peptides with a temperature-responsive polymeric carrier. The assembly complex was less toxic to human cells and more stable to enzymatic cleavage. This work may provide a promising drug delivery system for antimicrobial peptides.

Graphical abstract: A strategy for enhanced antibacterial activity against Staphylococcus aureus by the assembly of alamethicin with a thermo-sensitive polymeric carrier

Supplementary files

Article information

Article type
Communication
Submitted
06 ذو القعدة 1436
Accepted
22 محرم 1437
First published
27 محرم 1437

Chem. Commun., 2016,52, 896-899

A strategy for enhanced antibacterial activity against Staphylococcus aureus by the assembly of alamethicin with a thermo-sensitive polymeric carrier

P. Dong, Y. Zhou, W. He and D. Hua, Chem. Commun., 2016, 52, 896 DOI: 10.1039/C5CC07054F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements